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EEF1AKMT3

Gene
eef1akmt3
Protein
EEF1A lysine methyltransferase 3
Organism
Mus musculus
Length
232 amino acids
Function
Protein-lysine methyltransferase that selectively methylates EEF1A1 and EEF1A2 at 'Lys-165' in an aminoacyl-tRNA and GTP-dependent manner. EEF1A1 methylation by EEF1AKMT3 is dynamic as well as inducible by stress conditions, such as ER-stress, and plays a regulatory role on mRNA translation.
Similarity
Belongs to the methyltransferase superfamily. METTL21 family.
Mass
25.675 kDa
Sequence
MASSRTDPETEPESVFPREIRLFTDSYSESSRFCFCGHELSITQNFGSRLGVAARVWDAALSLCDYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPVALEQIQDNVHANVPPGGRARVCALSWGIDQHVFPGNYDLVLGADIVYLEPTFPLLLGTLRHLCGPHGTIYLASKMRAEHGAETFFRRLLPQHFHLELAQRDEDVNVNIYRARHREVAPAGQHPFC
Protein
EEF1A lysine methyltransferase 3: eef1akmt3

Gene
EEF1AKMT3
Protein
EEF1A lysine methyltransferase 3
Organism
Bos taurus
Length
226 amino acids
Function
Protein-lysine methyltransferase that selectively methylates EEF1A1 and EEF1A2 at 'Lys-165' in an aminoacyl-tRNA and GTP-dependent manner. EEF1A1 methylation by EEF1AKMT3 is dynamic as well as inducible by stress conditions, such as ER-stress, and plays a regulatory role on mRNA translation.
Similarity
Belongs to the methyltransferase superfamily. METTL21 family.
Mass
24.972 kDa
Sequence
MADSRPDPESEPDSVFPREVGLFADCYSEKSRFCFCGHVLNITENFGSRLGVAARVWDAALSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLVLEQIQGNVQANVPPGGRAQVRALSWGIDQHVFPGDYDLVLGADIVYLEPTFPLLLGTLRHLCGPHGTIYLASKMREEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHRGPRPA
Protein
EEF1A lysine methyltransferase 3: EEF1AKMT3

Gene
EEF1AKMT3
Protein
EEF1A lysine methyltransferase 3
Organism
Homo sapiens
Length
226 amino acids
Function
Protein-lysine methyltransferase that selectively methylates EEF1A1 and EEF1A2 at 'Lys-165' in an aminoacyl-tRNA and GTP-dependent manner. EEF1A1 methylation by EEF1AKMT3 is dynamic as well as inducible by stress conditions, such as ER-stress, and plays a regulatory role on mRNA translation.
Similarity
Belongs to the methyltransferase superfamily. METTL21 family.
Mass
24.911 kDa
Sequence
MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
Protein
EEF1A lysine methyltransferase 3: EEF1AKMT3

Gene
eef1akmt3
Protein
EEF1A lysine methyltransferase 3
Organism
Xenopus tropicalis
Length
224 amino acids
Function
Protein-lysine methyltransferase that selectively methylates EEF1A1 and EEF1A2 at 'Lys-165' in an aminoacyl-tRNA and GTP-dependent manner. EEF1A1 methylation by EEF1AKMT3 is dynamic as well as inducible by stress conditions, such as ER-stress, and plays a regulatory role on mRNA translation.
Similarity
Belongs to the methyltransferase superfamily. METTL21 family.
Mass
25.143 kDa
Sequence
MHPEAKEPDCGFSEVLPRELGSLFSDTYTEESHYAFCGTELRITQHYGANLGVAAPVWDAALFLCGYFEEQKLDFKGKKVIELGAGTGIVGILVSLLGGHVTLTDLPHALSQIQKNVSANVSSNNPPQVCALSWGLDQEKFPQDYDFVLGADIVYLHDTYPLLIQTLQYLCGPQTSIFLSSKMRQEHGTMHFFQDILPQYFASELVKRNKDEEINIYKVTRYQN
Protein
EEF1A lysine methyltransferase 3: eef1akmt3