Protein
Ethylmalonyl-CoA decarboxylase
Function
Decarboxylases ethylmalonyl-CoA decarboxylase, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level.
Similarity
Belongs to the enoyl-CoA hydratase/isomerase family.
Sequence
MRRCEVNSKPISEYFGIPCENREMAKCLLTSSLSVRTKLLQTGVSLYNTSHGFHEEEVKKILEQFPGGSIDLLKKQNGIGILTLNNPNKMNAFSGVMMLQLLERVIELENWTEGKGLIIHGAKNTFCSGSDLNAVKALSTPESGVALSMFMQNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGTSRLVEIIGSRQALKVLSGTLKLDSKEALNIGLTDEVLQPSDETTALEQAQEWLEKFVSGPPQVIRGLKKSVCSARELYIEEALQNERDVLETLWGGPANLEAIAKKGKHTK