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EAF3

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
401 amino acids
Function
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
Similarity
Belongs to the MRG family.
Mass
45.203 kDa
Sequence
MVDLEQEFALGGRCLAFHGPLMYEAKILKIWDPSSKMYTSIPNDKPGGSSQATKEIKPQKLGEDESIPEEIINGKCFFIHYQGWKSSWDEWVGYDRIRAYNEENIAMKKRLANEAKEAKKSLLEQQKKKKLSTSLGGPSNGGKRKGDSRSNASISKSTSQSFLTSSVSGRKSGRSSANSLHPGSSLRSSSDQNGNDDRRRSSSLSPNMLHHIAGYPTPKISLQIPIKLKSVLVDDWEYVTKDKKICRLPADVTVEMVLNKYEHEVSQELESPGSQSQLSEYCAGLKLYFDKCLGNMLLYRLERLQYDELLKKSSKDQKPLVPIRIYGAIHLLRLISVLPELISSTTMDLQSCQLLIKQTEDFLVWLLMHVDEYFNDKDPNRSDDALYVNTSSQYEGVALGM

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
401 amino acids
Function
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
Similarity
Belongs to the MRG family.
Mass
45.203 kDa
Sequence
MVDLEQEFALGGRCLAFHGPLMYEAKILKIWDPSSKMYTSIPNDKPGGSSQATKEIKPQKLGEDESIPEEIINGKCFFIHYQGWKSSWDEWVGYDRIRAYNEENIAMKKRLANEAKEAKKSLLEQQKKKKLSTSLGGPSNGGKRKGDSRSNASISKSTSQSFLTSSVSGRKSGRSSANSLHPGSSLRSSSDQNGNDDRRRSSSLSPNMLHHIAGYPTPKISLQIPIKLKSVLVDDWEYVTKDKKICRLPADVTVEMVLNKYEHEVSQELESPGSQSQLSEYCAGLKLYFDKCLGNMLLYRLERLQYDELLKKSSKDQKPLVPIRIYGAIHLLRLISVLPELISSTTMDLQSCQLLIKQTEDFLVWLLMHVDEYFNDKDPNRSDDALYVNTSSQYEGVALGM

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
387 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
43.183 kDa
Sequence
MVLATNSRCLAYHGPLLYEAKILMSYDPSKRGSKAKVEDGLPPTVEIGNVVNTHKRKRGPRASLPAAGATPDGDDSNDKNRHFSPKEGKPDVPADLADENEDKICYYVHYKGWKNTWDEWVGEERVLALNEDNIKLQKELKAAALAAAKKGKDFDALAPPEALSETASPAPTTKRKSMASKDSPAEGPRPVKRRGGLAALEDLEKEDDYLKRKEIALVVPDKLKAQLVDDWEFVTKDHQLVGLPRKVTVVDILKEFKKEAEAKYRPGSADADILNEVVSGIKLYFDRSLGSILLYRFEREQYLQITQSPDHSNKTMSEVYGAEHLLRLFVSLPGLIAMTNMDAQSVAVLKEHLEDFVRFLSTHQKTYFLKEAYTNASPAYEALSKGL

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
387 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
43.183 kDa
Sequence
MVLATNSRCLAYHGPLLYEAKILMSYDPSKRGSKAKVEDGLPPTVEIGNVVNTHKRKRGPRASLPAAGATPDGDDSNDKNRHFSPKEGKPDVPADLADENEDKICYYVHYKGWKNTWDEWVGEERVLALNEDNIKLQKELKAAALAAAKKGKDFDALAPPEALSETASPAPTTKRKSMASKDSPAEGPRPVKRRGGLAALEDLEKEDDYLKRKEIALVVPDKLKAQLVDDWEFVTKDHQLVGLPRKVTVVDILKEFKKEAEAKYRPGSADADILNEVVSGIKLYFDRSLGSILLYRFEREQYLQITQSPDHSNKTMSEVYGAEHLLRLFVSLPGLIAMTNMDAQSVAVLKEHLEDFVRFLSTHQKTYFLKEAYTNASPAYEALSKGL

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
369 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
42.81 kDa
Sequence
MVEYKPNQTVYAYHGPLIYEAKILKLKNGKDSFIINQDFQHEPLEEKPNSSGNHHHHHHSQHIAKFDPKKWQDQTCYYLHYQGWNSKWDEWVGIDRIMEYNEENKFKKLELDQLTKKKKAINNNEIIVNATTKNHTNNKNKKESNKRKSSSATTTSGVTAGTNNNKKQKSASTSTTNNTSGNSGTTSNKSKQILSRLNLNFPPELKHILVNDWEYITKDRKLVSLPSQYPINQILQDYKTYRTKQLTSNSDQLSILIEILTGLEIYFNKSLSLILLYKYEHLQYLNFLKQNIINPQQDILQSNIYGVEHLLRLIISFPGLLSTTTMDGISLSVLISELESLCRFIGDRLQLYQNNYEFTSPQYDSLARS

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
369 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
42.81 kDa
Sequence
MVEYKPNQTVYAYHGPLIYEAKILKLKNGKDSFIINQDFQHEPLEEKPNSSGNHHHHHHSQHIAKFDPKKWQDQTCYYLHYQGWNSKWDEWVGIDRIMEYNEENKFKKLELDQLTKKKKAINNNEIIVNATTKNHTNNKNKKESNKRKSSSATTTSGVTAGTNNNKKQKSASTSTTNNTSGNSGTTSNKSKQILSRLNLNFPPELKHILVNDWEYITKDRKLVSLPSQYPINQILQDYKTYRTKQLTSNSDQLSILIEILTGLEIYFNKSLSLILLYKYEHLQYLNFLKQNIINPQQDILQSNIYGVEHLLRLIISFPGLLSTTTMDGISLSVLISELESLCRFIGDRLQLYQNNYEFTSPQYDSLARS

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
358 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
40.334 kDa
Sequence
MAIVLDGKCLCYHGPLLYEAKVLRVYDEKNQTITSKDYKDVSIDDEKVEFDRPPEHMRQGQCYFVHYQGWKSSWDEWVGLDRIRPYNDENLELKKSLVEKARELKNNGGKKKSGSRPVGRPSKVEKGKKAASRTSNSGSGTNTSASSTSASNPASSSSSGTTAAASSSDKSDRKKATPVLNKRSHPKIHIKVPISLRSVLVDDWENVTKDRKLVQLPSERPIEHILSQFYADTSNSTSSVVEQAQLSEFLQGIKLYFNLSLGKLLLYRLERIQYAELLKAHSEKQYTEIYGIIHLLRLVTLLPEMMESSNVDDQTAKILVKQCDILLEWIAINIARKNFPVDPYINTSSQYEGVALSM

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
358 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
40.334 kDa
Sequence
MAIVLDGKCLCYHGPLLYEAKVLRVYDEKNQTITSKDYKDVSIDDEKVEFDRPPEHMRQGQCYFVHYQGWKSSWDEWVGLDRIRPYNDENLELKKSLVEKARELKNNGGKKKSGSRPVGRPSKVEKGKKAASRTSNSGSGTNTSASSTSASNPASSSSSGTTAAASSSDKSDRKKATPVLNKRSHPKIHIKVPISLRSVLVDDWENVTKDRKLVQLPSERPIEHILSQFYADTSNSTSSVVEQAQLSEFLQGIKLYFNLSLGKLLLYRLERIQYAELLKAHSEKQYTEIYGIIHLLRLVTLLPEMMESSNVDDQTAKILVKQCDILLEWIAINIARKNFPVDPYINTSSQYEGVALSM

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
355 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
40.74 kDa
Sequence
MFEVGGKCLAYHGPLLYEAKILRRWNPKLEKVEYSVPLKSGEEDGLPESMNREEFYYYIHYQGWKSSWDEWVSVDRIMELTEANIELKKQLVMEAKKASLAQQQKTKNGGSAKRGGGGAHSESNHGGRRSGSGDRRDSNAEERGIVPSEGPFRTSSVMSYNFSRNKLRIHIPMILESMLVDDWEIVTKEKKISNLPNPFPVETILDRFYKDVATRTTSPVELSLVEEYVYGLKQYFNEAIGNLLLYKLERLQYEQVFYPTPEQQQAMTPVERSLSGRRPGQLYGVLHLLRLISILPEMLSNCVGMDTQAINVILRHTEKLLLWLVDRIEDLLPHKVHKSYYTNTSSQYEGVALGL

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
355 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
40.74 kDa
Sequence
MFEVGGKCLAYHGPLLYEAKILRRWNPKLEKVEYSVPLKSGEEDGLPESMNREEFYYYIHYQGWKSSWDEWVSVDRIMELTEANIELKKQLVMEAKKASLAQQQKTKNGGSAKRGGGGAHSESNHGGRRSGSGDRRDSNAEERGIVPSEGPFRTSSVMSYNFSRNKLRIHIPMILESMLVDDWEIVTKEKKISNLPNPFPVETILDRFYKDVATRTTSPVELSLVEEYVYGLKQYFNEAIGNLLLYKLERLQYEQVFYPTPEQQQAMTPVERSLSGRRPGQLYGVLHLLRLISILPEMLSNCVGMDTQAINVILRHTEKLLLWLVDRIEDLLPHKVHKSYYTNTSSQYEGVALGL

Gene
eaf3
Protein
Chromatin modification-related protein eaf3
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
330 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
38.333 kDa
Sequence
MAPASQSTYQKDERVLCFHHEILYEAKILDVRHTNAEDKKSPFEYLVHYKGWKNTWDDWVPQDRLRKFTDENRELATTLRREAEAAFRQKSTKTTLKRKAGSDRGSARDSEERQTSVPGRVTKRARDNEIEKEEHFYTRPSVRIVMPDNLKSLLVDDWENVTKNQQVVALPAKASVNQILEDFVAEEKPKRTSSADLDVLEEVIMGIKEYFDKALDKILLYRFEREQYKALRKKWEAGSGEYSEKGPLDVYGAEHLTRLFATMPELIAQTNMDLQSTNRLREELSKFTLWLSKNSDKYFATRYMTATNEYVEKSRGNPSAAATAATTRLV

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
330 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
37.53 kDa
Sequence
MLYTDGEKVLCFHGPLIYAAKILKAEKWTGEENVTGQVGPHYLVHYDGWKKTWDEWVPETRLLKHNDENLARKATLQEAAKAGSLISSAEKSAASTSAASSLKRAKDSELPDRKSASRGTKRSREHVEAEEEFLKRPEVKISLPDELKLQLVDDWENITKNGQLVPLPRNPCVKDILDDYRKHYLASKRSDPSKQRSPQLVDEVLKGLKLYFDRSLGQNLLYRFERAQYVDYRKKNGPKMGDGDVGNARTANGSMGGEMEPSNVYGAEHLLRLFVTLPMIIVHTSMDAESISLLKEHLAEFLSYIVREKHRLFVREYETASPAYHRISST

Gene
eaf3
Protein
Chromatin modification-related protein eaf3
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
330 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
38.333 kDa
Sequence
MAPASQSTYQKDERVLCFHHEILYEAKILDVRHTNAEDKKSPFEYLVHYKGWKNTWDDWVPQDRLRKFTDENRELATTLRREAEAAFRQKSTKTTLKRKAGSDRGSARDSEERQTSVPGRVTKRARDNEIEKEEHFYTRPSVRIVMPDNLKSLLVDDWENVTKNQQVVALPAKASVNQILEDFVAEEKPKRTSSADLDVLEEVIMGIKEYFDKALDKILLYRFEREQYKALRKKWEAGSGEYSEKGPLDVYGAEHLTRLFATMPELIAQTNMDLQSTNRLREELSKFTLWLSKNSDKYFATRYMTATNEYVEKSRGNPSAAATAATTRLV

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
330 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
37.53 kDa
Sequence
MLYTDGEKVLCFHGPLIYAAKILKAEKWTGEENVTGQVGPHYLVHYDGWKKTWDEWVPETRLLKHNDENLARKATLQEAAKAGSLISSAEKSAASTSAASSLKRAKDSELPDRKSASRGTKRSREHVEAEEEFLKRPEVKISLPDELKLQLVDDWENITKNGQLVPLPRNPCVKDILDDYRKHYLASKRSDPSKQRSPQLVDEVLKGLKLYFDRSLGQNLLYRFERAQYVDYRKKNGPKMGDGDVGNARTANGSMGGEMEPSNVYGAEHLLRLFVTLPMIIVHTSMDAESISLLKEHLAEFLSYIVREKHRLFVREYETASPAYHRISST

Gene
eaf3
Protein
Chromatin modification-related protein eaf3
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
327 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
38.147 kDa
Sequence
MAPAGQTTYQKDERVLCFHHEILYEAKILDLRHTDPDDRKSPYEYLVHYKGWKNTWDDWVPQDRLRKFTEENRELATTLRREAEAALRQKSTKTSLKKKGGSDHSSARGSEERQTSVPGRGTKRARDNDIEKEEHFYTRPSVRIVMPDNLKSLLVDDWENVTKNQQVVALPAKSSVNQILDDYLKEERPKRTGSSEVDVLEEVVMGIRDYFDKSLDKILLYRFEREQYRVLRKRWESETADKGPLDVYGAEHLTRLFATMPELIAQTNMDLQSTNRLREELSKFTIWLSKNSNHYFATRYVTASNEYIEKSRGVPNPAPGTATSRLV

Gene
eaf3
Protein
Chromatin modification-related protein eaf3
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
327 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
38.147 kDa
Sequence
MAPAGQTTYQKDERVLCFHHEILYEAKILDLRHTDPDDRKSPYEYLVHYKGWKNTWDDWVPQDRLRKFTEENRELATTLRREAEAALRQKSTKTSLKKKGGSDHSSARGSEERQTSVPGRGTKRARDNDIEKEEHFYTRPSVRIVMPDNLKSLLVDDWENVTKNQQVVALPAKSSVNQILDDYLKEERPKRTGSSEVDVLEEVVMGIRDYFDKSLDKILLYRFEREQYRVLRKRWESETADKGPLDVYGAEHLTRLFATMPELIAQTNMDLQSTNRLREELSKFTIWLSKNSNHYFATRYVTASNEYIEKSRGVPNPAPGTATSRLV

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
316 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
36.163 kDa
Sequence
MSGDDAAVFKPNARVLAYHGPLIYEAKVIKIHEKNKTFIEDGEGKHQPIEGGNLPEEYYSVNAYFVHYKGWKAKWDEWVGPDRILEYNEANVQAQKELKEQLTKAKIKPKVKAEPAVASTGTKKRGMPVSSASTVTKKKKTDPNRVNEVSIFMKPELKYILVDDWEFITKERKIINIPSSRPVTVILNDYLQSKKDQDTSHQTMDVINEIMQGLELYFNKSLSLILLYKFERLQYMNLLKEHGDDLRPSELYGVEHLLRLFVALPGLIAQTTMDSVSINVLVKQSKDILEFITDNMSVYLNDYVNVSPAYDSLARS

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
316 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
36.163 kDa
Sequence
MSGDDAAVFKPNARVLAYHGPLIYEAKVIKIHEKNKTFIEDGEGKHQPIEGGNLPEEYYSVNAYFVHYKGWKAKWDEWVGPDRILEYNEANVQAQKELKEQLTKAKIKPKVKAEPAVASTGTKKRGMPVSSASTVTKKKKTDPNRVNEVSIFMKPELKYILVDDWEFITKERKIINIPSSRPVTVILNDYLQSKKDQDTSHQTMDVINEIMQGLELYFNKSLSLILLYKFERLQYMNLLKEHGDDLRPSELYGVEHLLRLFVALPGLIAQTTMDSVSINVLVKQSKDILEFITDNMSVYLNDYVNVSPAYDSLARS

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
310 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
34.437 kDa
Sequence
MAFEIDGKCLCYHGPLLYEARVLRVYDPASQTYRDRTRTGVPLEEEDGLPAESRGREHWFVHYQGWKSTWDEWVGQERIRPYNDENLALKRQLVQDAKAAAAAAKRAKARPGKRERSPAPAAPAAPAQGPRLAVRMPVELKALLVDDWERITKERKLVALPCAPTVGDILDAYYRERTAQLASPVAQTLLHEFVEGVHLYFDQCLSHLLLYRLERLQFDEACGGAAPAASGLPAPPEPRPSAVYGGVHLLRLLSMMPELICGTTMDEKSCHTVVAQCESLLAWMATHADDLVSGDYINTSAQYEGVALGM

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
310 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
34.437 kDa
Sequence
MAFEIDGKCLCYHGPLLYEARVLRVYDPASQTYRDRTRTGVPLEEEDGLPAESRGREHWFVHYQGWKSTWDEWVGQERIRPYNDENLALKRQLVQDAKAAAAAAKRAKARPGKRERSPAPAAPAAPAQGPRLAVRMPVELKALLVDDWERITKERKLVALPCAPTVGDILDAYYRERTAQLASPVAQTLLHEFVEGVHLYFDQCLSHLLLYRLERLQFDEACGGAAPAASGLPAPPEPRPSAVYGGVHLLRLLSMMPELICGTTMDEKSCHTVVAQCESLLAWMATHADDLVSGDYINTSAQYEGVALGM

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
305 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
35.135 kDa
Sequence
MAGAVPQFMVDEYVLAYHGPLLYEARVILAEVWDESNTLLGTVGPHYFIHYKGWKQTWDEWVPESRLLKLNEAGFAKRRALLDAQAKKGRSTGGSGGTGSPGAGKGGLKDKKKDTKKRGRDAMESESDFMKRPEVKIVIPDVLKLVLVDDWENVTKNNQLVALPRKPNVRELLEEYRQYASASKKQERSDRATALLSEIISGITLYFDKALGNNLLYRFERAQYVEQKRQNPEKPMSEIYGAEHLLRLFVNFGPFIAYTNIDTESLNILRDYINDIMQWMIKEQKRLFMKEYEETTTHYQNLSRS

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
305 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
35.135 kDa
Sequence
MAGAVPQFMVDEYVLAYHGPLLYEARVILAEVWDESNTLLGTVGPHYFIHYKGWKQTWDEWVPESRLLKLNEAGFAKRRALLDAQAKKGRSTGGSGGTGSPGAGKGGLKDKKKDTKKRGRDAMESESDFMKRPEVKIVIPDVLKLVLVDDWENVTKNNQLVALPRKPNVRELLEEYRQYASASKKQERSDRATALLSEIISGITLYFDKALGNNLLYRFERAQYVEQKRQNPEKPMSEIYGAEHLLRLFVNFGPFIAYTNIDTESLNILRDYINDIMQWMIKEQKRLFMKEYEETTTHYQNLSRS

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
305 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
35.135 kDa
Sequence
MAGAVPQFMVDEYVLAYHGPLLYEARVILAEVWDESNTLLGTVGPHYFIHYKGWKQTWDEWVPESRLLKLNEAGFAKRRALLDAQAKKGRSTGGSGGTGSPGAGKGGLKDKKKDTKKRGRDAMESESDFMKRPEVKIVIPDVLKLVLVDDWENVTKNNQLVALPRKPNVRELLEEYRQYASASKKQERSDRATALLSEIISGITLYFDKALGNNLLYRFERAQYVEQKRQNPEKPMSEIYGAEHLLRLFVNFGPFIAYTNIDTESLNILRDYINDIMQWMIKEQKRLFMKEYEETTTHYQNLSRS

Gene
EAF3
Protein
Chromatin modification-related protein EAF3
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
305 amino acids
Function
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the MRG family.
Mass
35.135 kDa
Sequence
MAGAVPQFMVDEYVLAYHGPLLYEARVILAEVWDESNTLLGTVGPHYFIHYKGWKQTWDEWVPESRLLKLNEAGFAKRRALLDAQAKKGRSTGGSGGTGSPGAGKGGLKDKKKDTKKRGRDAMESESDFMKRPEVKIVIPDVLKLVLVDDWENVTKNNQLVALPRKPNVRELLEEYRQYASASKKQERSDRATALLSEIISGITLYFDKALGNNLLYRFERAQYVEQKRQNPEKPMSEIYGAEHLLRLFVNFGPFIAYTNIDTESLNILRDYINDIMQWMIKEQKRLFMKEYEETTTHYQNLSRS