DTX3

Protein DETOXIFICATION 3

476 amino acids

Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.

51.468 kDa

MEEPFLLQDEHLVPCKDTWKSGQVTVELKKVSSLAAPMAAVTIAQYLLPVISVMVAGHNGELQLSGVALATSFTNVSGFSILFGLAGALETLCGQAYGAKQYEKIGTYTYSATASNIPICVLISVLWIYIEKLLISLGQDPDISRVAGSYALWLIPALFAHAFFIPLTRFLLAQGLVLPLLYCTLTTLLFHIPVCWAFVYAFGLGSNGAAMAISVSFWFYVVILSCYVRYSSSCDKTRVFVSSDFVSCIKQFFHFGVPSAAMVCLEWWLFELLILCSGLLPNPKLETSVLSICLTTASLHYVIPGGVAAAVSTRVSNKLGAGIPQVARVSVLAGLCLWLVESAFFSTLLFTCRNIIGYAFSNSKEVVDYVANLTPLLCLSFILDGFTAVLNGVARGSGWQHIGALNNVVAYYLVGAPVGVYLAFNRELNGKGLWCGVVVGSAVQAIILAFVTASINWKEQAEKARKRMVSSENRLA

Dtx3

Probable E3 ubiquitin-protein ligase DTX3

347 amino acids

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Belongs to the Deltex family.

37.982 kDa

MSFVLSRMAACGGSCKNKVTVSKPVWDFLSKETPARLARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPELHRPGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREDAEEQETTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD

DTX3

Probable E3 ubiquitin-protein ligase DTX3

347 amino acids

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Belongs to the Deltex family.

37.988 kDa

MSFVLSRMAACGGTCKNKVTVSKPVWDFLSKETPARLARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPEMHRAGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREEAEEQESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD

DTX3

Probable E3 ubiquitin-protein ligase DTX3

347 amino acids

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Belongs to the Deltex family.

37.988 kDa

MSFVLSRMAACGGTCKNKVTVSKPVWDFLSKETPARLARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPEMHRAGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREEAEEQESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD