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DhpD

Gene
DhpD
Protein
Guanine deaminase
Organism
Drosophila melanogaster
Length
448 amino acids
Function
Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Also has 7,8-dihydropterin deaminase activity, which plays a role in synthesis of the red eye pigment aurodrosopterin.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
Mass
48.885 kDa
Sequence
MATVFLGTVVHTKSFSEFESFEGGFLAVDDAGKIIGVGQDYHAWASSNPAHAKGLTEVHLSDYQFLMPGFVDCHIHAPQFAQLGLGLDMPLLDWLNTYTFPLEAKFSNHQYAQQVYQGVVEATLRCGTTLASYFATNHLESTLTLAREAVRQGQRALIGKVCSNCNSPEFYVETAEESVSATLAFVEGVRKLGSPMVMPTITPRFALSCSKELLKSLGDIAKRFDLHIQSHISENLEEIEMVKGIFKTSYAGAYDEAGLLTNKTVLAHGVHLEDDEVALLKVRGCSVAHCPTSNTMLSSGLCDVQRLVSGGVSVGLGTDVSGGNSVSIQDVLLRALDVSKHLDFFKKQNIRGTGVSKTQDFNYHQLKYKQALYLATLGGAKALSLDHLTGNFALGKDFDALLVDVSVVDKPLRRLSVDELVEKFIYTGSDRNIVEVFVAGKRIKQGYQ