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Defa5

Gene
DEFA5
Protein
Defensin-5
Organism
Homo sapiens
Length
94 amino acids
Function
Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.
Similarity
Belongs to the alpha-defensin family.
Mass
10.071 kDa
Sequence
MRTIAILAAILLVALQAQAESLQERADEATTQKQSGEDNQDLAISFAGNGLSALRTSGSQARATCYCRTGRCATRESLSGVCEISGRLYRLCCR

Gene
DEFA5
Protein
Defensin-5
Organism
Pan troglodytes
Length
94 amino acids
Function
Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity).
Similarity
Belongs to the alpha-defensin family.
Mass
10.063 kDa
Sequence
MRTIAILAAILLVALQAQAESLQERADEATTQKQSGEDNQDLAISFAGNGLSALRTSGSQARATCYCRIGHCTILESLSGVCEISGRLYRLCCR

Gene
Defa5
Protein
Alpha-defensin 5
Organism
Mus musculus
Length
93 amino acids
Function
Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
Similarity
Belongs to the alpha-defensin family.
Mass
10.519 kDa
Sequence
MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS