DRC5

Gene

DRC5

Protein

Dynein regulatory complex subunit 5

Organism

Chlamydomonas reinhardtii

Length

390 amino acids

Function

Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (PubMed:23427265, PubMed:25411337). May play a role in the assembly of N-DRC (PubMed:23427265).

Similarity

Belongs to the DRC5 family.

Mass

43.503 kDa

Sequence

MAAPNLITPLRDICVKVVAANFEGCPTFGPLPDKYVKRIIDILPLDLPLELVGSLIADEDYWRRRSQARWKNCEVAAHGYSWKQLFFERNLMEFLEQYDPAVTDLSSLKRLLTYSRRFVQTVHIRQLPSHLDLQILFECMVNTPSSLALSYNLKEVGMDYDRSLFGMKLSDCRALAKALEHTETLTHLDLSNNSLDDDKVRMLASGLVENLSITHLNLSHNKIADRGVRALAKLLDGHSVISLLELHDNQIHTEGAESLARAFKSNQCLLSVNLRLNRMGDEGCKAVVESVRGSPTLQRLNISANAAGPGTAAAVVALLRLNNTLTELDVSCNQFGEDACGNVRRALEQNGSVRLMDVRMTGINPDDEMAIAENLRARQERVDKARVLGK

Protein

Dynein regulatory complex subunit 5: DRC5