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DNAAF2

Gene
DNAAF2
Protein
Protein kintoun
Organism
Homo sapiens
Length
837 amino acids
Function
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Similarity
Belongs to the PIH1 family. Kintoun subfamily.
Mass
91.114 kDa
Sequence
MAKAAASSSLEDLDLSGEEVQRLTSAFQDPEFRRMFSQYAEELTDPENRRRYEAEITALERERGVEVRFVHPEPGHVLRTSLDGARRCFVNVCSNALVGAPSSRPGSGGDRGAAPGSHWSLPYSLAPGREYAGRSSSRYMVYDVVFHPDALALARRHEGFRQMLDATALEAVEKQFGVKLDRRNAKTLKAKYKGTPEAAVLRTPLPGVIPARPDGEPKGPLPDFPYPYQYPAAPGPRAPSPPEAALQPAPTEPRYSVVQRHHVDLQDYRCSRDSAPSPVPHELVITIELPLLRSAEQAALEVTRKLLCLDSRKPDYRLRLSLPYPVDDGRGKAQFNKARRQLVVTLPVVLPAARREPAVAVAAAAPEESADRSGTDGQACASAREGEAGPARSRAEDGGHDTCVAGAAGSGVTTLGDPEVAPPPAAAGEERVPKPGEQDLSRHAGSPPGSVEEPSPGGENSPGGGGSPCLSSRSLAWGSSAGRESARGDSSVETREESEGTGGQRSACAMGGPGTKSGEPLCPPLLCNQDKETLTLLIQVPRIQPQSLQGDLNPLWYKLRFSAQDLVYSFFLQFAPENKLSTTEPVISISSNNAVIELAKSPESHGHWREWYYGVNNDSLEERLFVNEENVNEFLEEVLSSPFKQSMSLTPPLIEVLQVTDNKIQINAKLQECSNSDQLQGKEERVNEESHLTEKEYIEHCNTPTTDSDSSIAVKALQIDSFGLVTCFQQESLDVSQMILGKSQQPESKMQSEFIKEKSATCSNEEKDNLNESVITEEKETDGDHLSSLLNKTTVHNIPGFDSIKETNMQDGSVQVIKDHVTNCAFSFQNSLLYDLD
Protein
Protein kintoun: DNAAF2

Gene
DNAAF2
Protein
Protein kintoun
Organism
Bos taurus
Length
829 amino acids
Function
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Similarity
Belongs to the PIH1 family. Kintoun subfamily.
Mass
90.97 kDa
Sequence
MAKEAASSPLEDLDLSGEEVQRLTSAFQDPEFRRMFSEYAEELTDPENRRRYEEEITALERERGVEVRFVHPEPGHVLRTSLDGTRRCFVNVCSNALVGAPSSQPGSGSAVSGRQWSLPYSLAPGREYAWGRGTRYTVYDVVFHPDAIALARRHERFRQMLDATALEAVEKQFGVKLDRRNAKTLKIKYKGTPDAAVLRTPLPGGAPARPEGEPESPFPDFPYPYRYPAAGASAAVPRPQAPSPPEAVRQPAPTEPRYSVVQRHHVDLQDYRCSRDSAPGTVPQELVVTIELPLLRSAEQAALEVTGKLLCLDSRKPDYRLRLSLPYPVDDSRGKAQFNKARRQLVVTLPVAPTASRPEPAASPEEAADPPGTDGAACASACRGEAGPAGVCAGDAISGPSRTRAADAGITTPDAPGKERVAKSEERDFGGQEISTTGTREEPPSGAGNSPGDRGGGALSTSWGDLDAGLSVGSASVRPTLGVEARETREGTGREPAYRAMGGPGTDRGEALCPPLQCSQDEESLTLLVQVPWILLQSLQGEVNPLWYKLSFSTQDLVYYSFFLQFTPENKLSTKEPEVSISSNNAVINLAKSPECHGYWREWYYGLNNYCLEERLFVNEDNVNEFLEEVLSPPFKQTLPLTPPLIEVLQVTDSKIEIHAKLQECSNSEQLHEKEERVHEGSPLTEKENTEHATISTTDSASSVAVTVLEADRCGSATCLQQGALDVSQKLFAESQQPKSEKEREFIKDKSAVYANERKDNLKEPVITEEKELDGNHPSSLLNKTAVRDTPGFDHIKETNMQDGSVQIIKDHVTHCSFSFQNNLLYDLD
Protein
Protein kintoun: DNAAF2

Gene
Dnaaf2
Protein
Protein kintoun
Organism
Rattus norvegicus
Length
817 amino acids
Function
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Similarity
Belongs to the PIH1 family. Kintoun subfamily.
Mass
89.349 kDa
Sequence
MAKTAASSALEDLDLSGEEVQRLTSAFQDPEFRRMFSDYAAEITDPENRRRYEEEITALERERGVEVRFVHPEPGHVLRTSLDGEHRCFVNVCSNSLVGAPSSRPGPGRGGTAAGSHWSLPYSLAPGRQYAGRNGNRYTVYDVVFHPEALALARSHERFREMLDATALEAVEQQFGVRLDRRNAKTLKIKYKGTPEAAVLRTPLPEGVRAQPEGELPGLLPYPPYPYHYPAAAESTARSPASPAPKAVQRPEPTEPRCSVVQRHHVDLQDYRCSRDAAPSTVPHELVVTIELPLLRSAERAELEVKGKLLCLDSRNPDYRLRLSLPYPVDDGRGRAQYNKARRQLVVTLPVALAVARQDFSTTPEGPTAETGTDNIACTSAGDLAGAREESADSSGADHGRKSCVVAPDAGTAKAEGELVPEPEQDFGGDSVTPLGPGEGTTPENRSLLYSAFQSGDAESLAERSGVYGDLSVQTSEEQEGTCHDTSGSDMGGPGTESIKPLCPPLQCNQDEDSLTLLIQVPGIQPQSLHGDLSPFSYELCFSTQDSGYSFTLQFAPENKLSTKEPAISISLNNAVIVLAKSPESHGLWREWYWGLNKDSLEERLFIDEENVNEFLEEVVRSPLKPARSLSPPLIEVLQVTEEQIQIHAKLQECSDPDGLQGKEKGVKEECPLSEKENTEHSTTSTADSNSSVAVEGLKINTCGAVGLQQGCPDVPHVLSGKRLQSEAKMDPEFIRESSTAYSAEEKENIKEPVITKEKKIGGDHLSSLPNKTAVQNTHDFDTIKETNMQDGSVQIIKDHTTHCAFDFQNSLLYDLD
Protein
Protein kintoun: Dnaaf2

Gene
Dnaaf2
Protein
Protein kintoun
Organism
Mus musculus
Length
814 amino acids
Function
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Similarity
Belongs to the PIH1 family. Kintoun subfamily.
Mass
88.327 kDa
Sequence
MAKAAASSALEDLDLSREEVQRFTSAFQDPEFRRMFSEYAAEITDPENRRRYEEEITALERERGVDVRFVHPEPGHVLRTSLDGEHRCYVNVCSNSLVGVPSSRPGPGRGGTAAGSHWSLPYSLAPGRQYAGRNGARYTVYDVVFHPEALALARSHERFREMLDATALEAVEQQFGVRLDRRNAKTLKIKYKGMPEAAVLRTPLPGGVPAQPEGEPPGLFPDPPYPYRYPAAAAANTARSPASPAPEAVQRPEPTEPRCSVVQRHHVDLQDYRCSRDAAPSTVPHELVVTIELPLLRSVERAELEVKGKLLCLDSRNPDYRLRLSLPYPVDDGRGKAQYNKARRQLVVTLPVALADARQEPPAATPEEPAEETGTDDVARTSAGDFAAAREESADGTGADHGEKSGVGAPDPGAAHAEGELVPEPEQDFGGDSVAPLDLGKGTSPGDRSLPYSAFPGGDTESLCGDPGVQTNEEQERTRHDTAGSAMGDPGTESIAPVCPPLQCNQDEDSLTLLIQVPGILPQTLHGHLSPVGYELCFSTQDSGYSCTLQFAPENKLSTREPETSVSLNNAVIVLAKSPESHGLWREWYCGLNKESLEERLFINEENVNGFLEEVLCSPLKQARSLAPPLIEVLQATDEQVQIHAELQECSDPAGLQGKGKGVREGCPLSEAEAADQSATSPAASDSAAAVEALKINTHGSAVDLQHGCPEVPHVLSGKPLQPEAKMDPEFIRESSTTYSTEEKENIREPVISKGEKINGDHPSSLLNKTVVQNIPDFDTIKETNMQDGSVQIIRDHTTHCAFSFQNPLLYDLD
Protein
Protein kintoun: Dnaaf2

Gene
dnaaf2
Protein
Protein kintoun
Organism
Xenopus laevis
Length
788 amino acids
Function
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Similarity
Belongs to the PIH1 family. Kintoun subfamily.
Mass
88.59 kDa
Sequence
MAEKLQNLELSSEELDRFTKAFQDPKFREMFVQYAEEIRDPENRRKYEQEISQMESERGMDIKFIHPKPGYVLLTSVNGVQKCYLNICSNDLLQKPECKPGKDGEGKAGLHWSLPYSLSAGREDLGKDGSKHVIYDVVFHPDTLHIASKNEKFKMIVDSTSLEAVASQFDVKLDKANVRTLSMKYKGVPNPSVLRKPLLGTTPKHGDPEDPLSFPYPYDVPTAVGKEKKDQKRVIKEEHKQHVTTSEQDPDIQIATTPNYTVRHRSYVDLQDFRDSRDSTPSPVPKELVITVDLPLLNSAESVNLHIAGKNLSLESEKPAYKLNVKLPYVVEDNQGKAQFNKARRQLIITVPVIQHNILTLMQDHFEEARGEKDLRGAESSVLHEEYTDNGSRTSACGTENKLEPLISCLNEEENNSEGLTSESNLDTGAPYLPEISPNQNTLDREEVVYGLTEDVPSMPSDTLVCPTFSCSQDPTSLTLIAHVRDIDENSISTDVGSNHYHIRCSVKQSTSSYDLLVTFLPHDIINPNEVYVNISENNALIGLTKSPESVGFWKMLYFGVSGQPLQERRFVSEDNINEVLACSIPLSQVSPSTQEHQPLIEVLEMTDERTHIRINKPKTECVVSAEHKEHCTDHSEHERDVGVERSNIAVGDTTEHYSNQVSPCRENTELDRDHTSERYEEPESTSCTGESTSDQQQKDSNLVFPGDSSAENKMACLKSSEQTTQESDLAEDDMPDRSDHTQNFDSRPASSSVLKEIGKKDGSVQVISDHTTQCPFQFQNSLLFDLD
Protein
Protein kintoun: dnaaf2

Gene
dnaaf2
Protein
Protein kintoun
Organism
Xenopus tropicalis
Length
785 amino acids
Function
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Similarity
Belongs to the PIH1 family. Kintoun subfamily.
Mass
88.104 kDa
Sequence
MAAKLQDLELSSEEVDRFSKAFKDPTFREMFIQYAEEISDPENRKKYEQEIYKMENERGMDIKFIHPKPGYVLLSSVNGVQKCYLNICSNDLIQKPEFKPGKDGEGKAGLHWSLPYSLSPGRDDLSKDWSKHVIYDVVFHPDTLHIASKNGKFKGIVDSTALEAVASQFNVTLDKANVRTLSMKYKGVPNPSVLRKPLPEASPKSRDLEDPLCFPYPYDVPTAVGTEKKDQKRVIQKECKQHLVTPEQDPNVQVAATPNYTVRHRSYVDLQDFRDSRDSTPSPVPKELVITVDLPLLNSAAGVNLHIAGKNLSLESEKPAYKLNVKLPYAVEDNQGKAQFNKVKKQLIITVPVIQHNILSLMQDHFQEARGEKDNQNKAEHSVLNKEHTDNSGITSARGTEKLLELEEENQFEGLASISSMDTGASHLPEILPNLNTFGKEQVVNQMNEDTPNVPTDNLVCPTFTCSQDPTSLTLIVHVRDIDENSICADVGSNHYHIRCYRKQSRAFYDLLVTFLPHDIIISNEVSVNISEDNVVIGLTKCPESFGFWKKLYFGVSGQSLQERRFVIEENINKVLACSIPLSQVSPSIQEHQPLIEVLEMTDEKTHIRLNEPKIEYVDSAEHNEQCTDHSESERDTSLELPNVDGKDSAEQCSSQVSPCKHNIELGREHTSERDKEPKPTSCTAESTSGQQPNDSHLVCPGDNCAQDSNAENKMACLKSSVQTTQESDLDEDDMPDNSDHLQNSASSNNILKEISSKDGSVQVISDHTTHCPFQFQNSLLFELD
Protein
Protein kintoun: dnaaf2

Gene
dnaaf2
Protein
Protein kintoun
Organism
Oryzias latipes
Length
588 amino acids
Function
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Similarity
Belongs to the PIH1 family. Kintoun subfamily.
Mass
66.584 kDa
Sequence
MEVGKKLELSITADEVEVLSKAIKNEKFQEMLSNYFQEISSPENVKTYQEEVTLLEQKRGNSIEFIHPSPFRALETSVDGKQRCFINICACDKVGKPESKTVRTVQRFGEKWSLPHLLQPGRQNCERKGNISTIYDVCFHPETLHLADKSEKFMDMVKEVAIQGIQKAFKVLLDKSNLKEMDIKYKGVPQSCVIRKPIPGYEAKEPPEERDLSPSTSHLPENSIDVPSKLLQKQPEEPIKPIYAIKYRSVIDLQDFRVSRESARSLRPKEIVITIDLPLLPTVHGMVLEVEEKRLLLESENPSYRLELHLSYPVDENNGKAKFNKHQRQLTVTLPVQPPLEAPQLPGGSPNPTSDPQNENQTRVEERVEEMAEKGGEQHQRGNDNGAAQGRRQVLEDQNGEKEGKKIQKRNERPEHEVKNETLRKKHDEKFELQDVQQENKGNCSNTKEVKCCRRTKDSLDSLIPTTAASPDGQKKHILTQETEKPKGSVEIPTSSQEYLKVPVTSAATAANVNASDETSKRKPTEEQLEDADEDVLPAEQRFQEPEEINVPAAGTLRQNNAAGNEKINDPHTSAGFVLQNKLMYELD
Protein
Protein kintoun: dnaaf2

Gene
dnaaf2
Protein
Protein kintoun
Organism
Danio rerio
Length
566 amino acids
Function
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Similarity
Belongs to the PIH1 family. Kintoun subfamily.
Mass
62.676 kDa
Sequence
MDADRLAELQLTRAEMRRIGEALQDRRFRELLTEYVEEISSPENRRRYEEEIRRLEEERGAAVQFIHPTPHHVLKGRGPSGKCFINICSDQLIEKPRSEAATDDRGRSGHSWRIPYSLTPGRAGRDAAGAPCVLFDAVFHPDALLMAENNARFMTLIHRTATGGIQDNFRIRLEHVTRLKMMKYKGEPQPTMIRRPNPGQTEAADRGPQQTTGPQQPTGPQQPTDPQQPTDTQQPTDPQQTTGPQQTTGPQQTTGPHQPTDPQQTTGPQQPTDPQQPTGPHQPTDPQQTTDPPPTAPQYRLKYRSVLDLQDYRCCRDSGSAGRPTAIIIEVEVPRLRSAQEAELRVEERRLLLEAPTAEYRLELPLAYPVEEERAEAQFNHTHRLLTVTLPVLKRRRVEEEERRAEEEESRKGGDEDGELHPDCGPDPPMMELQTEDTHTPAADTHTPAADTHTPAADTHTPAAETGAGLGSGVALLSSSNVISVCGADVHQQLEEPGDPSAHTDPADTHPADTDPADTDPAHTDPADTDPADTDPAHTDPAHTDPEMESRIAGLHLQNTLCFQLD
Protein
Protein kintoun: dnaaf2