Protein
Doublesex- and mab-3-related transcription factor 1
Organism
Xenopus tropicalis
Function
Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and germ cell proliferation. Acts both as a transcription repressor and activator (By similarity).
Similarity
Belongs to the DMRT family.
Sequence
MQNNEEPFSKTRSSGQHPSGVHGKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPIAAELLIKREHGGSSSCLMLESSSTQTTSTSTSGSTTSSEGKMLIQEIPSITSRGHLESTSDLVMDSPYYSNFYQPPLYPYYNNLYNYPPYQMAVATESTSGNDMGGISGPSMKNSHRNHPAAYVPSQSGNQWQMKNGENRFPGHSASSQFRMHSYYPPYLGQSVPNPVCVPPFLTFEEIPSYSEAKASVALSPPSSQDSGIISLSSNSPVSNESTKGAAEQEPNSESSAFTVTTAGEDRE