Protein
1,4-dihydroxy-2-naphthoyl-CoA thioesterase 2
Organism
Arabidopsis thaliana
Function
Catalyzes the hydrolysis of the thioester bond of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) in peroxisomes, a necessary step to form the naphthoquinone ring of phylloquinone (vitamin K(1)). Displayed also slight thioesterase activity towards benzoyl-CoA. Is not active on phenylacetyl-CoA, succinyl-CoA and palmitoyl-CoA thioesters.
Similarity
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
Sequence
MDPKSPEFIIDQPLKILGFVFDELSATRVSGHLTLTEKCCQPFKVLHGGVSALIAEALASLGAGIASGFKRVAGIHLSIHHLRPAALGEIVFAESFPVSVGKNIQVWEVRLWKAKKTETPDNKIMVSTSRVTLFCGLPIPDHVKDAPDELKKVISKL