DHCR7

Gene

dhcr7

Protein

7-dehydrocholesterol reductase

Organism

Danio rerio

Length

478 amino acids

Function

Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).

Similarity

Belongs to the ERG4/ERG24 family.

Mass

55.189 kDa

Sequence

MMASDRVRKRHKGSANGAQTVEKEPSKEPAQWGRAWEVDWFSLSGVILLLCFAPFLVSFFIMACDQYQCSISHPLLDLYNGDATLFTIWNRAPSFTWAAAKIYAIWVTFQVVLYMCVPDFLHKILPGYVGGVQDGARTPAGLINKYEVNGLQCWLITHVLWVLNAQHFHWFSPTIIIDNWIPLLWCTNILGYAVSTFAFIKAYLFPTNPEDCKFTGNMFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSYAAKQQELYGYVTNSMILVNVLQAVYVVDFFWNEAWYLKTIDICHDHFGWYLGWGDCVWLPFLYTLQGLYLVYNPIQLSTPHAAGVLILGLVGYYIFRVTNHQKDLFRRTEGNCSIWGKKPTFIECSYQSADGAIHKSKLMTSGFWGVARHMNYTGDLMGSLAYCLACGGNHLLPYFYIIYMTILLVHRCIRDEHRCSNKYGKDWERYTAAVSYRLLPNIF

Protein

7-dehydrocholesterol reductase: dhcr7

Gene

DHCR7

Protein

7-dehydrocholesterol reductase

Organism

Bos taurus

Length

475 amino acids

Function

Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).

Similarity

Belongs to the ERG4/ERG24 family.

Mass

54.271 kDa

Sequence

MAAKSQPSAPKTKSTSGLTNGNAAAQGQWGRAWEVDWFSLASVIFLLLFAPFIVYYFIMACDQYGCSLTVPVADLATGRARLADIWARTPPVTAKAAQIYTAWVTLQVLLYMLLPDFCHKFLPGYVGGVQEGAVTPAGAVNKYEINGLQAWLLTHLLWFANAHLLGWFSPTIIFDNWIPLLWCANILGYTVSTFAMVKGYLFPTDARECKFTGNFFYNYMMGVEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMVLVNILQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLPTYYALGVLLLGLLGYYIFRMTNHQKDLFRRTDGRCLIWGRKPKAIECSYTSADGQRHHSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYIIFMAILLTHRCLRDEHRCANKYGRDWEHYTAAVPYRLLPGIF

Protein

7-dehydrocholesterol reductase: DHCR7

Gene

DHCR7

Protein

7-dehydrocholesterol reductase

Organism

Homo sapiens

Length

475 amino acids

Function

Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).

Similarity

Belongs to the ERG4/ERG24 family.

Mass

54.489 kDa

Sequence

MAAKSQPNIPKAKSLDGVTNDRTASQGQWGRAWEVDWFSLASVIFLLLFAPFIVYYFIMACDQYSCALTGPVVDIVTGHARLSDIWAKTPPITRKAAQLYTLWVTFQVLLYTSLPDFCHKFLPGYVGGIQEGAVTPAGVVNKYQINGLQAWLLTHLLWFANAHLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMVKGYFFPTSARDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQRELHSHVTNAMVLVNVLQAIYVIDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPHAVGVLLLGLVGYYIFRVANHQKDLFRRTDGRCLIWGRKPKVIECSYTSADGQRHHSKLLVSGFWGVARHFNYVGDLMGSLAYCLACGGGHLLPYFYIIYMAILLTHRCLRDEHRCASKYGRDWERYTAAVPYRLLPGIF

Protein

7-dehydrocholesterol reductase: DHCR7

Gene

dhcr7

Protein

7-dehydrocholesterol reductase

Organism

Xenopus laevis

Length

473 amino acids

Function

Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).

Similarity

Belongs to the ERG4/ERG24 family.

Mass

54.823 kDa

Sequence

MGERRRANASRGDKKVANGEKQHVGQWGRAWEVDYFSLASVIFLLAFAPLIVYYFVMSCDQYQCALTAPVLDLYSGKARLSDIWDKTPALTWTAVKIYLAWVSFQVFLYMFLPDILHKFVPGYEGGVQEGARTPAGLINKYQVNGLQAWTITHLLWFANAYHFHWFSPTIVIDNWIPLLWCANLLGYSVATFALVKANFFPTNANDCKFTGNFFYDYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSYAAKQQELYGQVTNSMILVNVLQAIYVVDFFWNESWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYNPVELSTTAAVAVLLLGLIGYYIFRMTNHQKDLFRRTNGNCKIWGKKPKSIECFYVSADGKRHYSKLMISGFWGVARHLNYTGDLMGSLAYCLACGFDHLLPYFYFIYMTILLVHRCIRDEHRCSSKYGKDWKLYTSAVPYRLLPGLF

Protein

7-dehydrocholesterol reductase: dhcr7

Gene

dhcr7

Protein

7-dehydrocholesterol reductase

Organism

Xenopus tropicalis

Length

473 amino acids

Function

Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).

Similarity

Belongs to the ERG4/ERG24 family.

Mass

54.785 kDa

Sequence

MGERRRANASRGDKKVANGEKPHVGQWGRAWEVDYFSLAAVLFLLAFAPLIVYYFVMSCDQYQCALTAPVLDLYWGKAQLSDIWDKTPALTWGAAKIYIVWVSFQVFLYMLVPDILHKFVPGYEGGVQEGARTPAGLINKYQVNGLQAWTITHLLWFANAYHFHWFSPTIIIDNWVPLLWCANLLGYSVATFALLKAYFFPTNAHDCKFTGNFFYDYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSYAAKQQELYGQVTNSMILVNVLQAIYVVDFFWNESWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYNPVELSTATAVGVLLLGLIGYYIFRMTNHQKDLFRRTNGNCKIWGKKPKSIECSYTSADGKRHYSKLMISGFWGVARHLNYTGDLMGSLAYCLACGFDHLLPYFYFTYMTILLVHRCIRDEHRCSSKYGKDWKLYTDAVPYRLLPGLF

Protein

7-dehydrocholesterol reductase: dhcr7

Gene

Dhcr7

Protein

7-dehydrocholesterol reductase

Organism

Mus musculus

Length

471 amino acids

Function

Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).

Similarity

Belongs to the ERG4/ERG24 family.

Mass

53.919 kDa

Sequence

MASKSQHNAPKVKSPNGKAGSQGQWGRAWEVDWFSLASIIFLLLFAPFIVYYFIMACDQYSCSLTAPALDIATGHASLADIWAKTPPVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPGYVGGVQEGAITPAGVVNKYEVNGLQAWLITHILWFVNAYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPNALGILLLGLVGYYIFRMTNHQKDLFRRTDGRCLIWGKKPKAIECSYTSADGLKHHSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYTAAVPYRLLPGIF

Protein

7-dehydrocholesterol reductase: Dhcr7

Gene

Dhcr7

Protein

7-dehydrocholesterol reductase

Organism

Rattus norvegicus

Length

471 amino acids

Function

Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).

Similarity

Belongs to the ERG4/ERG24 family.

Mass

54.155 kDa

Sequence

MASKSQHNASKAKNHNVKAESQGQWGRAWEVDWFSLVSVIFLLLFAPFIVYYFIMACDQYSCSLTAPILDVATGRASLADIWAKTPPVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPGYVGGVQEGAITPAGIVNKYEVNGLQAWLITHFLWFVNAYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPNALGVLLLGLVGYYIFRMTNHQKDLFRRTDGHCLIWGKKPKAIECSYTSADGLKHRSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYVAAVPYRLLPGIF

Protein

7-dehydrocholesterol reductase: Dhcr7

Gene

DHCR7

Protein

Probable 7-dehydrocholesterol reductase

Organism

Acanthamoeba polyphaga mimivirus

Length

447 amino acids

Function

Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).

Similarity

Belongs to the ERG4/ERG24 family.

Mass

51.692 kDa

Sequence

MNSYQTNTATSWGRNHIPTLLDNLTTAAMFMFCPFIILVFYLITYGEYLGSIGDFYLDIINGDWQTIWSNIPSFKINVLGACLLWIVFQLILSKLPDTIHRFVPHYVGGIKAGHITPAGNLVYYNINGLQAFIITHVLVIMSCYYGLFSPTIIMDNWGSIFWSVNIIGYLITFLAYFKALTFSSHPSDNKFTGKLFYDIVMGIEFNPEIFGTDLKLFFNGRPGIIAWNLINLSCAMKQYENFGYVSNSMILVIILQLIYIVDFFYNENWYVHTVDIAHDHFGWMLAWGDTVWLPFGYTLQAGYLMNNPIDLSTGFFNLVFVMGIIGYIIFRTANYQKDKYRSNTQGVKYIPCTYQTADGLNRASKLIYSGLWGVSRHMNYTGDIILSTAYCLACGFSHFIPYFYCVYMTILLVTRCLRDEQRCSRKYGKYWKMYTKRVPYRFIPGIY

Protein

Probable 7-dehydrocholesterol reductase: DHCR7