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DEUP1

Gene
DEUP1
Protein
Deuterosome assembly protein 1
Organism
Homo sapiens
Length
604 amino acids
Function
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity).
Similarity
Belongs to the CEP63 family.
Mass
70.977 kDa
Sequence
MENQAHNTMGTSPCEAELQELMEQIDIMVSNKKMDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLAMTQNYEGQLQSLKAQFSKLTNNFEKLRLHQMKQNKVPRKELPHLKEEIPFELSNLNQKLEEFRAKSREWDKQEILYQTHLISLDAQQKLLSEKCNQFQKQAQSYQTQLNGKKQCLEDSSSEIPRLICDPDPNCEINERDEFIIEKLKSAVNEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKSELQSRDDLLRIIEMERLQLHRELLKIGECQNAQGNKTRLESSYLPSIKEPERKIKELFSVMQDQPNHEKELNKIRSQLQQVEEYHNSEQERMRNEISDLTEELHQKEITIATVTKKAALLEKQLKMELEIKEKMLAKQKVSDMKYKAVRTENTHLKGMMGDLDPGEYMSMDFTNREQSRHTSINKLQYENERLRNDLAKLHVNGKSTWTNQNTYEETGRYAYQSQIKVEQNEERLSHDCEPNRSTMPPLPPSTFQAKEMTSPLVSDDDVFPLSPPDMSFPASLAAQHFLLEEEKRAKELEKLLNTHIDELQRHTEFTLNKYSKLKQNRHI

Gene
DEUP1
Protein
Deuterosome assembly protein 1
Organism
Macaca fascicularis
Length
603 amino acids
Function
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity).
Similarity
Belongs to the CEP63 family.
Mass
70.882 kDa
Sequence
MENQAHNTMGTSPCEAELQELMEQIDIMVSNKKMDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLAMTQNYEGQLQSLKAQFSKLTNSFEKLRLHQMKQNKVPRKELPHLKEELPFELSNLNQKLEEFRAKSREWDKQEILYQTHLISLDAQQKLLSEKCNQFQKQAQSYQTQLNGKKQCLEDSSSEIPRLICDPDPNCEIGERDEFIIEKLKSAVSEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKSELQSRDDLLRIIEMERLQLHRELLKIGECQNAQGNKKRLESSHLPSIKEPERKRKELFSVMQDQPNHEKELNKIRSQLQQEEEYHNSEQERMRNEISDLTEELHQKEITIATVTKKAALLEKQLKMELEIKEKMLAKEQVSDMKYKAVRTENTHLKGMMGDLDPGRYMSMDFTNREHSRHTSINKLEYENERLRNDLAKLRVNGKSTRTNQNTYEETGRYAYQSQIKVEKNEERLSHDCEPNRSTSPLPPLTFQTKEMTSPLVSDDDVFPLSPPDMSFPASLAAQHFLLEEEKRAKELEKLLNTHIDELQRHTEFTLNKYSKLKQNRHI

Gene
Deup1
Protein
Deuterosome assembly protein 1
Organism
Mus musculus
Length
601 amino acids
Function
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis.
Similarity
Belongs to the CEP63 family.
Mass
69.678 kDa
Sequence
MENQAHTTAGASPCEAELQELMEQIDIMVSNKKLDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLVMTQNYEGQLQTLKAQFSKLTSNFEKLRLHQMKQNQIHRKESSSKEELPFELSSLNQKLEEFRAKSREWDKQEVLYQTHLVSLDAQQKLLSEKCSQFQKQAQNYQTQLNGKKQCAEDSSSEIPRLVCESDPGCEATQRDEFIIEKLKSAVSEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKSELQSRDDLLRIIEMERLHLHRELLRMGEVQTAQDNRKRVESSYSPSPKEAERKRKELFPMVSDQPNHEKELSKMRSQLYQEEGLCSEQERLRSEISELTQELHQKEVTIATVMKKAALLERQLKIELEIKERMLAKQQVSDRRYKAVRTENTHLKGMMGDLDPARYLAVDLSNKKHSQCTSINKLEYENERLRSDLAKLHGNGKAAWPNQSSYGEAGAYVFQSQLKTETSGDRISQDCELNRSPTPLSPLPFQTKEMASPLVGDNEVLALSPPDISFRASLAAQHFLMEEERRAKELEKLLNTHIDELQRHTEFTLNKYTKLKQSRHI

Gene
Deup1
Protein
Deuterosome assembly protein 1
Organism
Rattus norvegicus
Length
601 amino acids
Function
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity).
Similarity
Belongs to the CEP63 family.
Mass
70.105 kDa
Sequence
MENQAHTTAGASPCEAELQELMEQIDIMVSNKKLDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLVMTQNYEGQLQTLKAQFSKLTNNFEKLRLHQMKQNQSHRKEASNKDETPFELSSLNQKIEEFRAKSREWDKQEILYQTHLVSLDAQQKLLSEKCNQFQKQAQNYQTQLNGKQQRPEDSSPETPRLVCESSPGCEATQRDEFIIEKLKSAVSEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKNELQSRDDLLRIIEMERLHLHRELLKMGELQTVQDNRKRVESSYSPSTKEPERKRKELFSVVSDQPNHEKELNKMRSQLYQEEDLCSEQERMRNEISELTQELHQKEVTIATIMKKAALLERQLKIELEIKEKMLAKQQISDRRYKAVRTENTHLKGMMGDLDPARYLTVDFSNKEHSRHTSINKLEYENERLRSDLAKLHINGKAAWSNQSSYEGAGAYIYQSQLKTETGGDRISEDCEMNRSPTPLSPLPFQTKEMTSPLAGDNEVLPLSPPDISFRASLAAQHFLMEEEKRAKELEKLLNTHIDELQRHTEFTLNKYTKLKQSRHI

Gene
deup1
Protein
Deuterosome assembly protein 1
Organism
Xenopus tropicalis
Length
596 amino acids
Function
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core.
Similarity
Belongs to the CEP63 family.
Mass
69.022 kDa
Sequence
MFTNIHSIARNSSCENELEELMHQIDIMVSHRKVEWEKHVKVLEQKLEAQDRELTEARNLVDEKNHEIGILCKKLEGVDTAQHEMAQNYERQLQALKFQLCKLKKSYEKLHFHQEKHQKNENAAQERSRCELQWLTQKIEEFKARSREWEKQRVFYQDQLKSLDEQRKTLAEKCQLFQKESLSYQEQLSSQKQLQSEAITNNQSEMRRLRCLLDTSQETIRSDGVIIENLKSTVKEITLSRDSLKDENQQLLQELRRCQKQSQNMEAQLYKAKLELQSCNDLLRVPALEERQAQKETANLANQKTAQGEEASFQVTDPRMNYMTSEPEHKSFNLSKSEKYQAENDLHGTEAKNSDLERLRKDIGDLTAKLNQKDVTIATVSRKVSRLERELELKGAQNRQTSMPLSQKDVIAELESEMPQIHAVNKAPQTDSGEVDPWISIKCGEHDKPQKHRSFHGENNSLKPTNYADTRNHSVGSEWESEKSLCPWNTPTLGSATDDDCDLVDNENEWLSLYNSTLYPGLDLPPISYACDQLKDSTNSSLAGSSLISAAEKFLLEETRRASDFEKILNSHIEEMKRNSESTVSRYQSHGQSRHI