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DEP6

Gene
DEP6
Protein
Depudecin biosynthesis cluster-specific transcription activator DEP6
Organism
Alternaria brassicicola
Length
646 amino acids
Function
Transcription factor that positively regulates the expression of the gene cluster that mediates the biosynthesis of depudecin, a highly oxidized eleven-carbon linear polyketide that acts as a histone deacetylase (HDAC) inhibitor and makes a small contribution to pathogenesis (PubMed:19737099).
Mass
72.538 kDa
Sequence
MRSSSAGTPFTAQYACEICRERKVRCDRALPKCRRCDRLNQPCSYNQAHQRRTRDEQLKQLQERLAKTEAQLAMNTTAAPLSVRSQSRSEGTELASSTRWIGTPDSFTPNSCSRRSSQYQLPTTSTSQSQLGSVLGTTAANTPMDLDNIRGMSATSGMSTNGSSLFDSDLFTSFTEGADSNMTFAWTNQPLMALEPLDNMLLNRPQSAPPNGSEEDLSPTDLSLLHNHYFESVYFSFPFINRDRFTAEKTGSRSPATTALVYAVALAGCTRSLQDHNRQSTCYGLARNYAERCEQEDHLNDLNFLQALLLIGRFEAMNRKLERSGLTLGRAAMLCKLLKLHQMDKSEHSQGMQNRETQSGPRLALPHTKDPVLLEERRRTFWGLYILQSYVRTRTGWEFQLEDTKNLQINLPSPGLLRSDLEPLKMPSLLNISTEPAPEITSYAGCVLMVELALRCFDNGQKRDTPGFWDDYCALVKKTDDLFKTLKRHLNATSIREDPVAFSLYLNLRATEIFSHDSAITKNEEQGLPPLMVAESQRRATTAAFQICSAVGLNLPSPWKADSDIIMLQAIFIAWPLTMALKALYRELVRGGIRETVNGVVASIRLLFAALDHIEESDGHWHQCVTNVEAKLQEWDEKNSFDSLAL
Protein
Depudecin biosynthesis cluster-specific transcription activator DEP6: DEP6

Gene
DEP6
Protein
Depudecin biosynthesis cluster-specific transcription activator DEP6
Organism
Fusarium langsethiae
Length
611 amino acids
Function
Transcription factor that positively regulates the expression of the gene cluster that mediates the biosynthesis of depudecin, a highly oxidized eleven-carbon linear polyketide that acts as a histone deacetylase (HDAC) inhibitor and makes a small contribution to pathogenesis (PubMed:19737099, PubMed:28460114).
Mass
67.814 kDa
Sequence
MIRQFSAGSSFTARHACEICRQRKVRCDRALPRCRRCERLNQACVYSPISQRRTRDEQLQELQERLAKTEAQLALDAPRGPASSMSSQSRSDSAAPAASRVPSVSASVPNSAATNPMDMVGTRSSNTSMDLPVNTSPMLDIDLFTAGADSNMALDWNPYLTALEPLDNLLPNRLSPRSLPQNGREEDISLAELNALHNYYFESVYFSFPFLNRDRFAGESTGNGPAINALIYSVALAGCTHSSPQHTKVSIYYTLARNYAEKCERDGQLNDLNFLQALLFIGRFEAMEGKVESSWMTLGRAAMLARLLRLPQMDRLEESTESQDGSGLSLLETTDPALLEERRRTFWALYILQSYIKTRTGWQCMLGDIKTFQINLPSPGLLRSDLTPLKMPFISEIGTEPCPEVSSYAGCVLMVDLALRCLDHAQGHGATNFWDGYCALVKNTDELFGMLKQHLNATSIRKDPVAFSLYLNLRATEIFSHESAIARSKEQGLPPLMTAESQRRATAAAFQISTAVRLNLPSPWKVDSDIIMLQAIFIAWPLAMALKAFYRELEHGGSRDSVNGVVTSSRLLFAALGHIEESGGHWHQSVAHVEAKLQELDEKNGFNSLAL
Protein
Depudecin biosynthesis cluster-specific transcription activator DEP6: DEP6