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DDB_G0288371

Gene
DDB_G0288371
Protein
VPS74-like protein DDB_G0288371
Organism
Dictyostelium discoideum
Length
262 amino acids
Function
Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. May be involved in vacuolar protein sorting (By similarity).
Similarity
Belongs to the GOLPH3/VPS74 family.
Mass
29.609 kDa
Sequence
MNPDNDNDSLPLLTLPEQLFLLILNPETGKLPYTFVPLFHGFVGCGIAELQLMDKVIVTKQNSQSFNNNKMLIKVIDHSKTGDTFLDYILSKLSNSFAQKGLQMATAILTISVGLNKMKRITETIAQSLIKKGFIRGTLKRSVLFKNKSIYEVIDYQAKLSVESSICKVLSTPPDYPDNCLRELIILLTFKQYEDFLIKPKLMDSLISRLYHPEQCAHIKANLRLINKNFYKEPSEVHLTNDPSVKMLSLVIGGIRNAITSE