DCUN1D3

Gene

DCUN1D3

Protein

DCN1-like protein 3

Organism

Bos taurus

Length

304 amino acids

Function

Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane.

Mass

34.304 kDa

Sequence

MGQCVTKCKNPSSTLGSKNGDRDPSSKSHGRRSASHREEQLPTCGKPGGDILVNGTKKAEAAPEACQLPTSSGDAGREPKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEGLCPEEQT

Protein

DCN1-like protein 3: DCUN1D3

Gene

DCUN1D3

Protein

DCN1-like protein 3

Organism

Homo sapiens

Length

304 amino acids

Function

Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane (PubMed:25349211). When overexpressed in transformed cells, may promote mesenchymal to epithelial-like changes and inhibit colony formation in soft agar (PubMed:25349211).

Mass

34.291 kDa

Sequence

MGQCVTKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEGLCPEEQT

Protein

DCN1-like protein 3: DCUN1D3

Gene

Dcun1d3

Protein

DCN1-like protein 3

Organism

Mus musculus

Length

304 amino acids

Function

Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane.

Mass

34.439 kDa

Sequence

MGQCVTKCKNPSSTLGSKNGDRDPSNKSHSRRGASHREEQVPPCGKPAGDILVNGTKKAEAATEACQLPTSSGDAGRESKTNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREVEGRGTLSSGQEGLCPEEQT

Protein

DCN1-like protein 3: Dcun1d3

Gene

DCUN1D3

Protein

DCN1-like protein 3

Organism

Pongo abelii

Length

304 amino acids

Function

Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane.

Mass

34.277 kDa

Sequence

MGQCVTKCKNPSSTLGSKNGDRDPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEGLCPEEQT

Protein

DCN1-like protein 3: DCUN1D3

Gene

Dcun1d3

Protein

DCN1-like protein 3

Organism

Rattus norvegicus

Length

304 amino acids

Function

Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane.

Mass

34.35 kDa

Sequence

MGQCVTKCKNPSSTLGSKNGDRDPSSKSHSRRGASHREEQVPPCGKPAGDILVNGTKKAEAATEACQLPTSSGDAGRESKTNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREVEGRGALSSGPEGLCPEEQT

Protein

DCN1-like protein 3: Dcun1d3

Gene

dcun1d3

Protein

DCN1-like protein 3

Organism

Xenopus laevis

Length

303 amino acids

Function

Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane.

Mass

34.627 kDa

Sequence

MGQCVTKCKNPSSTLGSKNGERESSKPHKRSSSHKEEHMSICGKASGEILVNGTKKGDASLEASQPLAVGVDTKKKEQGVGAELSSLQRIEELFRRYKDEREDAILEEGMERFCDDLCVDPTEFRVLVLAWKFQAATMCKFTRREFFEGCKSINADGIESICSQFPGLLNEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNKPLILDQWLEFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKSEEKTDCIPCLGTDHQSRDEQT

Protein

DCN1-like protein 3: dcun1d3

Gene

dcun1d3

Protein

DCN1-like protein 3

Organism

Xenopus tropicalis

Length

303 amino acids

Function

Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane.

Mass

34.591 kDa

Sequence

MGQCVTKCKNPSSTLGSKNGERESSKPHKRSSSHKDEHLSICGKASREILVNGTKKGDVSLEASQPLAAGGDTKKKEQGTGAELSSVQRIEELFWRYKDEREDAILEEGMERFCNDLYVDPTEFRVLVLAWKFQAATMCKFTRREFFEGCKAINADGIEGICARFPSLLNEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNKPLILDQWLDFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKNEEETKCIPCSGTDDQSTEGQT

Protein

DCN1-like protein 3: dcun1d3