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DCTD

Gene
dctD
Protein
C4-dicarboxylate transport transcriptional regulatory protein DctD
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
462 amino acids
Function
Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.
Mass
50.865 kDa
Sequence
MSPFAPFDAQTQVLLIDDDPHLRQALRQTLDLAGLKVATLDDARQLDTAQCKDWPGVVVSDIRMPGIDGMELLRQLHEQDADLPVILITGHGDVPLAVQAMRGGAYDFLEKPFPSDALLDSVRRALEVRRLVLENRTLRLALAERHELHGRLIGRSAGMQRLREQVGSLAAIQADVLVLGETGAGKEVVARALHDLSSRRDGPFVAINAGALAESVVESELFGHEAGAFTGAQKRRIGKFEYANGGTLFLDEIESMSLDVQVKLLRLLQERVVERLGSNQLIPLDIRIIAATKEDLRQAADQGRFRADLYYRLNVASLRIPPLRERGEDIPLLFRHFAEAGAMRHGLTPRELDAGQSARLLAYDWPGNVRELQNAAERFALGLGLSLDDGVLPDAADEPHNLSAKVEAFERSLIAAELERPHNSLRSVAEALGIPRKTLHDKLRKHGLPFNTPGENPPDDGE

Gene
dctD
Protein
C4-dicarboxylate transport transcriptional regulatory protein DctD
Organism
Rhizobium meliloti (strain 1021)
Length
460 amino acids
Function
Member of the two-component regulatory system DctB/DctD involved in the transport of C4-dicarboxylates. When activated by DctB acts in conjunction with sigma-54 to activate the transcription of dctA.
Mass
50.061 kDa
Sequence
MSAAPSVFLIDDDRDLRKAMQQTLELAGFTVSSFASATEALAGLSADFAGIVISDIRMPGMDGLALFRKILALDPDLPMILVTGHGDIPMAVQAIQDGAYDFIAKPFAADRLVQSARRAEEKRRLVMENRSLRRAAEAASEGLPLIGQTPVMERLRQTLKHIADTDVDVLVAGETGSGKEVVATLLHQWSRRRTGNFVALNCGALPETVIESELFGHEPGAFTGAVKKRIGRIEHASGGTLFLDEIEAMPPATQVKMLRVLEAREITPLGTNLTRPVDIRVVAAAKVDLGDPAARGDFREDLYYRLNVVTLSIPPLRERRDDIPLLFSHFLARASERFGREVPAISAAMRAYLATHSWPGNVRELSHFAERVALGVEGNLGVPAAAPASSGATLPERLERYEADILKQALTAHCGDVKETLQALGIPRKTFYDKLQRHGINRADYVERAGPGRPNAISKT

Gene
dctD
Protein
C4-dicarboxylate transport transcriptional regulatory protein DctD
Organism
Rhizobium leguminosarum
Length
448 amino acids
Function
Member of the two-component regulatory system DctB/DctD involved in the transport of C4-dicarboxylates. When activated by DctB acts in conjunction with sigma-54 to activate the transcription of dctA.
Mass
49.485 kDa
Sequence
MDTLMPVALIDDDKDLRRATAQTLELAGFSVSAYDGAKAALADLPADFAGPVVTDIRMPEIDGLQLFATLQGMDVDLPVILMTGHGDIPMAVQAIQDGAYDFIAKPFAADRLVQSVRRASEKRRLVLENRMLRKAAEDAQENLPLIGQTPVMENLRNILRHIADTDVDVLVAGETGSGKEVVAQILHQWSHRRKGNFVALNCGALPETVIESELFGHERGAFTGAQKRRTGRIEHASGGTLFLDEIESMPAATQVKMLRVLEMREITPLGTNEVRPVNLRVVAAAKIDLGDPAVRGDFREDLYYRLNVVTISIPPLRERRDDIPLLFSHFAARAAERFRRDVPPLSPDVRRHLASHTWPGNVRELSHYAERVVLGVEGGGAAAVPPQPTGATLPERLERYEAEIIRDTLSANDGDVRRTIEALGIPRKTFYDKLQRHGINRGGYSSRK

Gene
DCTD
Protein
Deoxycytidylate deaminase
Organism
Homo sapiens
Length
178 amino acids
Function
Supplies the nucleotide substrate for thymidylate synthetase.
Similarity
Belongs to the cytidine and deoxycytidylate deaminase family.
Mass
20.016 kDa
Sequence
MSEVSCKKRDDYLEWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPNGCSDDVLPWRRTAENKLDTKYPYVCHAELNAIMNKNSTDVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSKIVIDFDSINSRPSQKLQ

Gene
Dctd
Protein
Deoxycytidylate deaminase
Organism
Mus musculus
Length
178 amino acids
Function
Supplies the nucleotide substrate for thymidylate synthetase.
Similarity
Belongs to the cytidine and deoxycytidylate deaminase family.
Mass
20.059 kDa
Sequence
MSDISCKKRDDYLEWPEYFMAVAFLSAQRSKDPSSQVGACIVNTENKIVGIGYNGMPNGCSDDLLPWRRTAENKLDTKYPYVCHAELNAIMNKNSADVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSEETTAARLLFKLAGVTFRKFTPKYSKIVIDFDSINSRPSQKPQ

Gene
DCTD
Protein
Deoxycytidylate deaminase
Organism
Pongo abelii
Length
178 amino acids
Function
Supplies the nucleotide substrate for thymidylate synthetase.
Similarity
Belongs to the cytidine and deoxycytidylate deaminase family.
Mass
20.045 kDa
Sequence
MSEVSCKKRDDYLEWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPNGCSDDQLPWRRTAKNKLDTKYPYVCHAELNAIMNKNSTDVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFDMAGVTFRKFIPKCSKIVIDFDSINSRPSQKLQ

Gene
Dctd
Protein
Deoxycytidylate deaminase
Organism
Rattus norvegicus
Length
178 amino acids
Function
Supplies the nucleotide substrate for thymidylate synthetase.
Similarity
Belongs to the cytidine and deoxycytidylate deaminase family.
Mass
20.059 kDa
Sequence
MSDISCKKRDDYLEWPEYFMAVAFLSAQRSKDPSSQVGACIVNTENKIVGIGYNGMPNGCSDDLLPWRRTAENKLDTKYPYVCHAELNAIMNKNSADVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSEETTAARLLFKLAGVTFRKFTPKYSKIVIDFDSINSRPSQKPQ