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DCT

Gene
DCT
Protein
L-dopachrome tautomerase
Organism
Gallus gallus
Length
521 amino acids
Function
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels.
Similarity
Belongs to the tyrosinase family.
Mass
59.314 kDa
Sequence
MGALRWLFWVGLSYLSCCRLPRAEAQFPRVCMTVEAIRSKRCCPALGPDPGNVCGVLQGRGWCQGVQVDTQPWSGPYTLRNVDDRERWPLKFFNQSCWCTGNFAGYNCGDCKFGWTGPDCSVRKPPVVRKNIHSLTVEEREQFLDVLDRAKTTIHPDYVIATQHWMSLLGPSGEEPQIANCSIYNYFVWLHYYSVRDTLLGPGRPFTAIDFSHQGPAFVTWHRYHLLLLERDLQRLMGNESFALPYWDFATGRNTCDVCTDQLFGAPRPDDPGLISLNSRFSRWQIVCNSLDDYNRLVTLCNGSDEGLLQRRPRDSGEQLPTAEDVRRCLSRHEFDSPPFFRNSSFSFRNALEGFNKPEGALNSPMLNLHNLAHSFLNGTRVLPHAAANDPIFVVLHSFTDAIFDEWMKRFHPPDNAWPEELAPIGHNRLYNMVPFFPPVTNDQLFQTAEQLGYTYAIDLPGSLEESQAWAAMVGSTIGGALIALAVLVLLLVLFQHRKQRKGFEPLMNVRFSSKKYMEEA
Protein
L-dopachrome tautomerase: DCT

Gene
DCT
Protein
L-dopachrome tautomerase
Organism
Homo sapiens
Length
519 amino acids
Function
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA) (PubMed:8306979). Involved in regulating eumelanin and phaeomelanin levels.
Similarity
Belongs to the tyrosinase family.
Mass
59.145 kDa
Sequence
MSPLWWGFLLSCLGCKILPGAQGQFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQCTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCERKKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCSVYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESFALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCNGTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDKADGTLDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDAIFDEWMKRFNPPADAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTSDQLGYSYAIDLPVSVEETPGWPTTLLVVMGTLVALVGLFVLLAFLQYRRLRKGYTPLMETHLSSKRYTEEA
Protein
L-dopachrome tautomerase: DCT

Gene
DCT
Protein
L-dopachrome tautomerase
Organism
Sus scrofa
Length
519 amino acids
Function
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels.
Similarity
Belongs to the tyrosinase family.
Mass
58.573 kDa
Sequence
MVPFRWGLLLGCLGSALGPGAQAQFPRVCMTVGSLQAKECCPPLGAEPSNVCGSLEGRGRCAEVQADTRPWSGPYVLRNQDDRERWPRKFFDRTCRCTGNFAGYNCGDCKFGWTGPNCDQKKPLVVRQNIHSLTAQEREQFLGALDLAKNTPHPDYVITTQHWLGLLGPNGTQPQIANCSIYDLFVWLHYYSVRDTLLGPGRPYKAIDFSHQGPAFVTWHRYHLLWLERALQRLTGNESFAVPYWNFATGRNECDVCTDQLLGAARPDDPTLISQNSRFSSWEIVCDSLDDYNRRVTLCNGTYEGLLRRNQVGRNSEKLPSLKDIEDCLSLKQFDNPPFFQNSTFSFRNALEGFDKADGTLDSQVMSLHNLVHSFLNGTSALPHSAANDPVFVVLHSFTDAIFDEWMKRFSPPVDAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTADQLGYSYAIDLPVSVEGTPDWTTTLSVVMGMLVVLVGLSALLLFLQYRRLRKGYTPLMETQLSHKRYTEEA
Protein
L-dopachrome tautomerase: DCT

Gene
DCT
Protein
L-dopachrome tautomerase
Organism
Bos taurus
Length
517 amino acids
Function
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels.
Similarity
Belongs to the tyrosinase family.
Mass
58.787 kDa
Sequence
MSPLGWGLLLGCLGCALPSGARAQFPRVCMTVGSLQAKECCPPLGADPANVCGSREGRGQCAEVQTDTRPWSGPYVLRNQDDRERWPRKFFDRTCRCTGNFAGYNCGNCRFGWTGPKCDQKKPLVVRRDVHSLTPQEREQFLDALDLAKYTLHPDYVITTQHWLGLLGPNGTRPQIANCSIYDFFVWLHYYSVRDTLLGPGRPYKAIDFSHQGPAFVTWHRYHLLWLERDLQRLTGNESFALPYWNFATGRNECDVCTDQLLGAARQDDPTLISQNSRFSSWEIVCDSLNDYNRRVTLCNGTYEGLLKRNQMGRNSEKLPTLKDIQNCLSLKKFDSPPFFQNSTLSFRNALEGFGKADGTLDSQVMNFHNLVHSFLNGTSALPHSAANDPVFVVLHSFTDAIFDEWMKRFNPPVDAWPRELAPIGHNRMYNMVPFFPPVTNEELFLTADQLGYSYAIDLPVEETPDWTTVLSVVTGMLVVLVVLFALLLFLQYRRLRKGYTPLVETQLSNKRYTEEA
Protein
L-dopachrome tautomerase: DCT

Gene
Dct
Protein
L-dopachrome tautomerase
Organism
Mus musculus
Length
517 amino acids
Function
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA) (PubMed:1537333). Involved in regulating eumelanin and phaeomelanin levels.
Similarity
Belongs to the tyrosinase family.
Mass
58.51 kDa
Sequence
MGLVGWGLLLGCLGCGILLRARAQFPRVCMTLDGVLNKECCPPLGPEATNICGFLEGRGQCAEVQTDTRPWSGPYILRNQDDREQWPRKFFNRTCKCTGNFAGYNCGGCKFGWTGPDCNRKKPAILRRNIHSLTAQEREQFLGALDLAKKSIHPDYVITTQHWLGLLGPNGTQPQIANCSVYDFFVWLHYYSVRDTLLGPGRPYKAIDFSHQGPAFVTWHRYHLLWLERELQRLTGNESFALPYWNFATGKNECDVCTDELLGAARQDDPTLISRNSRFSTWEIVCDSLDDYNRRVTLCNGTYEGLLRRNKVGRNNEKLPTLKNVQDCLSLQKFDSPPFFQNSTFSFRNALEGFDKADGTLDSQVMNLHNLAHSFLNGTNALPHSAANDPVFVVLHSFTDAIFDEWLKRNNPSTDAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTAEQLGYNYAVDLSEEEAPVWSTTLSVVIGILGAFVLLLGLLAFLQYRRLRKGYAPLMETGLSSKRYTEEA
Protein
L-dopachrome tautomerase: Dct