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DBX1

Gene
DBX1
Protein
Homeobox protein DBX1
Organism
Bos taurus
Length
345 amino acids
Function
Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity).
Similarity
Belongs to the H2.0 homeobox family.
Mass
37.467 kDa
Sequence
MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRGSVPTPSMSPPRPGAPAALTDTGASDLGSPGPGSRRGGSPQTAVSPASEPTFLKFGVNAILSSAPRTETSPTLLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGDDDDEEDEGPGSPRPRLVYHAAPADPRHLRDPRLEAPLPTSPARSGSPDKASDFSDSEDDEEGEEEITVS

Gene
DBX1
Protein
Homeobox protein DBX1
Organism
Homo sapiens
Length
343 amino acids
Function
Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity).
Similarity
Belongs to the H2.0 homeobox family.
Mass
37.283 kDa
Sequence
MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPPSPAHSSSPGKPSDFSDSEEEEEGEEQEEITVS

Gene
Dbx1
Protein
Homeobox protein DBX1
Organism
Mus musculus
Length
335 amino acids
Function
Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons.
Similarity
Belongs to the H2.0 homeobox family.
Mass
36.334 kDa
Sequence
MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPTYLSRSIPAASLSPPSQEAPAALADSGTSDLGSPGSGSRRGSSPQTALSPASEPTFLKFGVNAILSSAPRRETSPALLQSPPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGDEEEDNPGARLAYHAPADPRHLLEGPLPASPAHSSSPGKPSDFSDSDEDEEGEEDEEITVS

Gene
Dbx1
Protein
Homeobox protein DBX1
Organism
Rattus norvegicus
Length
335 amino acids
Function
Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity).
Similarity
Belongs to the H2.0 homeobox family.
Mass
36.403 kDa
Sequence
MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPTYLPRSIPTASLSPPRQEAPTALADSGTSDLGSPGSGSRRGSSPQTALSPASEPTFLKFGVNAILSSAPRRETSPALLQSPPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGDEEEDSPGASLAYHAPPDPRHLLEGPLPASPAHSSSPGKPSDFSDSDEDEEGEEDEEITVS

Gene
dbx1
Protein
Homeobox protein DBX1
Organism
Xenopus laevis
Length
331 amino acids
Function
May function within the midpoint progenitor population to inhibit neuronal differentiation, possibly through modulating the function of Xash3.
Similarity
Belongs to the H2.0 homeobox family.
Mass
36.684 kDa
Sequence
MMFPSLLAPPAVYPNLLRPTPTLTLPQSIQTALSNHTSFLIEDLIRISRPAGFLPRAVPPPSMSPPTSESPNCMSETSDLARREGPNQTSISSNNSSPFLKFGVNAILSSSPRTESAQVLLPSAHPKPFTFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLVARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAGKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKFNPHPDLSDVSKKSSGEGEEEPLCPGNSPAHALPYQCPEHHLRLDTQLPSSPFNSSSASKPSDFSDSEEEGGEQEEEITVS