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Cox16

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Coccidioides immitis (strain RS)
Length
137 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
15.705 kDa
Sequence
MPVFQTKRFRPSTSAGSTLGDRIGQMYRAHLSKHPFLLFGLPFLSLMVAGSFVLTPATALRYERHDRKVQQVSQQEALALGIKGPDGDGENDIKMNPRRRVLGSEKEEYYRLMAKDLDNWEQKRVQRWKGEPDGRLS

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Paracoccidioides brasiliensis (strain Pb18)
Length
135 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
15.526 kDa
Sequence
MVFQAKRFRPSNSFGSTLSERLGAKYRANLSKHPFLLFGLPFISVIIAGSFVLTPATAMRYERFDRKVQQVSQEEAMGLGLKGPEGDDGVQIKRNPRRRILGSEKEEYYKLMAKDLDNWEQKRVKRFKGEPDGRL

Gene
cox16
Protein
Cytochrome c oxidase assembly protein cox16, mitochondrial
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Length
134 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
15.359 kDa
Sequence
MPVFQAKTFRRATTASSSLGERIGAAYRGGLPKHPFLLFGLPFIMVIVAGSFVLTPAAALRYERYDRKVKQLSQEEAMELGLKGPDGEEGIRRNPRRRILGDEREEYYRLMAKDLDNWEQKRVQRFKGEPDGKL

Gene
cox16
Protein
Cytochrome c oxidase assembly protein cox16, mitochondrial
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
Length
134 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
15.567 kDa
Sequence
MPVFQSKTFRRATTASSSLGERIGETYRARLPKHPFLLFGFPFVMIIVAGSFALTPAAALRYERYDRKVQQLSQEEAMNLGLRGPDGEEGIKRNPRRRIIGDEREEYYRLMAKDLDNWEQKRVQRFKGEPDGKL

Gene
cox16
Protein
Cytochrome c oxidase assembly protein cox16, mitochondrial
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
134 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
15.492 kDa
Sequence
MPAFPSKTYRRATTASSTLGEKLGEAYRARLPRHPFLLFGLPFIMVIVAGSFVLTPATALRYERYDRKVKQLSQEEAMDLGLKGPDGEEGIKRNPRRRIIGDDREEYYRLMAKDLDSWEQKRVQRFKGEPDGRL

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
130 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
14.887 kDa
Sequence
MPPFATRPLNSTKSHPIFAQIRRHPFILFGIPFIGIIVGSSFALQAFTQTRYDYQETKVKSVGKEEELGMKSGRRKIDLKEEYYFSMASVSQDDYEPVRVPRPVGVPEWGGGRSGEEAPMKGYRKEDRWV

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
130 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
14.887 kDa
Sequence
MPPFATRPLNSTKSHPIFAQIRRHPFILFGIPFIGIIVGSSFALQAFTQTRYDYQETKVKSVGKEEELGMKSGRRKIDLKEEYYFSMASVSQDDYEPVRVPRPVGVPEWGGGRSGEEAPMKGYRKEDRWV

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
128 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
15.377 kDa
Sequence
MSYSGNRVFRGKKEQEAYDKTLAGRYVKLVKKNHFLFFGLPFLVSIVAGSIYLQKFTSVKWEKYDEKYQQLGEEEMLNLIENKRTVDKKNDYYRLQGLLNDHTNQVADDYEIVRVQRRKEDEPVWDRQ

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
127 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
15.409 kDa
Sequence
MVHLGSKPFRGKREQEAYDRTYAGRYQKLLRKNHFLYFGLPFILSIVAGSLYLQKFTAVKWEKYDERYRQVGEEEMLSMIENKRPVDKKNDYYRLQGLLHDHENEVSSNEDYEIVRVKRKKEDEPVW

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
121 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
14.287 kDa
Sequence
MSLGSRTFRSKRQMAAFEKSLQGRYLKLLRRNPFLFYGVPFCTLMAVGSYCLSDFTAVKYEREDKKVRSVQEDELVKLRANRRTVDLKEEFYRLQGLADQDWEPVRVPRLPGESENVWDVE

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
118 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
14.109 kDa
Sequence
MLEQNKFKTKKQQQAWNKTLAGRYYNAMVKRPFLFFGLPFLTTIYAASVYFAEFTAYRYEIQDGKVKALSEEEALKLDKGRRKVDMKEEFYRLQQLGKQDDWEQVRVPRMKGESDNVF

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
118 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:12446688, PubMed:28821616). May participate in merging the COX1 and COX2 assembly lines (PubMed:28821616).
Similarity
Belongs to the COX16 family.
Mass
14.077 kDa
Sequence
MSFSGKKFRSRRQQLVYEASLAGRYKKALSKHPFLFFGLPFCATIVLGSFWLSSFTAIKYEQGDRKVQEINEEDILKIRKNQREFDIKEEYYRLQGLSEEDWEPVRVARLKDESENVW

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
118 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
14.019 kDa
Sequence
MALGGRSFRSKKQQLAYDRSFAGRYQKLLSKNPFIFFGLPFCGMMVLGSYWLAGISQVKFDRDDQKVQEMNEEEILKMKHGKREFDIKEEYYRLQGLAEEDWEPKRVERFKGESDNVF

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
118 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
14.18 kDa
Sequence
MSFGGKKFRSKRQQLAYEASLAGRYQKHMNKNPFLWFGLPFCSVIVLGSFWLSEFTAVRYQQKDQKVQEMKEDDLVKMKANQRQFDIKEEYYRLQGLGEQDWEPKRIPRFKGESENVW

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
Length
116 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
13.566 kDa
Sequence
MPGPFSSRSFAATLPNSIAARYRKQLQKHPFLLFGLPFMATIVAGSFMLTPATALRYERYDRKNQQITQEEAMGLRQERRKVNMKDEYYRLQAKDLEDWEQRRVKRLPGEPDGTLV

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
115 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
13.551 kDa
Sequence
MPAFQSKKFRSAADMNSIGMRYRNLMNKHPFLMFGLPFLTVIVAGSFVLTPATAVRYERYDRKVRQMTKDEELNVRRSARKVDMKEEYYRLAGKDLDDWEQKRVKRLPGENDGLL

Gene
cox16
Protein
Cytochrome c oxidase assembly protein cox16, mitochondrial
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
113 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
13.691 kDa
Sequence
MLFYRFKSWYRLQAKKSPFIYVGLPFLSSVLLVWSCLIPISQVKFNRRDEQVKSLSRDAELDIIKRRRKVDVNEEYYRILLDQLNLQNEEYENKRVKRLKGEPTWEGNSSDKE

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial
Organism
Bos taurus
Length
107 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
12.518 kDa
Sequence
MFGYAVRRALRKSKTLRYGVPMLLLIVGGSFGLREFSQIRYDAVKIKIDPELEKKLKMNKVSLESEYEKIKDSTFDDWKNIRGPRPWEDPDLLQGRNPEILKTNKTT

Gene
Cox16
Protein
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial
Organism
Mus musculus
Length
106 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
12.266 kDa
Sequence
MIAPAVLRALRKNKTLRYGVPMLLLVVGGSFGLREFSQIRYDAVTIKIDPELEKKLKVNKITLESEYEKIKDSTFENWKNIRGPRPWEDPQLLQGRNPETLKPKTT

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial
Organism
Pongo abelii
Length
106 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Similarity
Belongs to the COX16 family.
Mass
12.293 kDa
Sequence
MFAPAVMRAFRKNKTLGYGVPMLLLIVGGSFGLREFSQIRYDAVKSKMDPELEKKLKENKISLESEYEKIKDSKFDDWKNIRGPRPWEDPDLLQGRNPESLKTKTT

Gene
COX16
Protein
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial
Organism
Homo sapiens
Length
106 amino acids
Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:29355485, PubMed:29381136). Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2) (PubMed:29355485, PubMed:29381136). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6 (PubMed:29381136). Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines (PubMed:29381136).
Similarity
Belongs to the COX16 family.
Mass
12.293 kDa
Sequence
MFAPAVMRAFRKNKTLGYGVPMLLLIVGGSFGLREFSQIRYDAVKSKMDPELEKKLKENKISLESEYEKIKDSKFDDWKNIRGPRPWEDPDLLQGRNPESLKTKTT