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Ccl12

Gene
Ccl12
Protein
C-C motif chemokine 12
Organism
Mus musculus
Length
104 amino acids
Function
Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
Similarity
Belongs to the intercrine beta (chemokine CC) family.
Mass
11.659 kDa
Sequence
MKISTLLCLLLIATTISPQVLAGPDAVSTPVTCCYNVVKQKIHVRKLKSYRRITSSQCPREAVIFRTILDKEICADPKEKWVKNSINHLDKTSQTFILEPSCLG