Protein
Fructose-1,6-bisphosphatase, cytosolic
Organism
Arabidopsis thaliana
Function
Catalyzes the first irreversible reaction from fructose-1,6-bisphosphate to fructose-6-phosphate and inorganic phosphate and plays an important regulatory role in sucrose biosynthesis and metabolism (Probable). Its activity is essential to regulate starch levels (PubMed:25743161). Functions in fructose-mediated signaling independently of its catalytic activity in sugar metabolism. May act downstream of ABA2/GIN1, which is involved in abscisic acid (ABA) synthesis to regulate autotrophic transition and modulate early seedling establishment after seed germination (PubMed:21253566).
Similarity
Belongs to the FBPase class 1 family.
Sequence
MDHAADAHRTDLMTITRFVLNEQSKYPESRGDFTILLSHIVLGCKFVCSAVNKAGLAKLIGLAGETNIQGEEQKKLDVLSNDVFVNALVSSGRTSVLVSEEDEEATFVEPSKRGKYCVVFDPLDGSSNIDCGVSIGTIFGIYTLDHTDEPTTADVLKPGNEMVAAGYCMYGSSCMLVLSTGTGVHGFTLDPSLGEFILTHPDIKIPNKGNIYSVNEGNAQNWDGPTTKYVEKCKFPKDGSPAKSLRYVGSMVADVHRTLLYGGIFLYPADKKSPNGKLRVLYEVFPMSFLMEQAGGQAFTGKKRALDLVPEKIHERSPIFLGSYDDVEEIKALYAEEEKKN