Protein
3-O-acetylpapaveroxine carboxylesterase CXE2
Organism
Papaver somniferum
Function
Carboxylesterase involved in the biosynthesis of the benzylisoquinoline alkaloid noscapine (PubMed:25485687). Converts 3-O-acetylpapaveroxine to narcotine hemiacetal (PubMed:25485687).
Similarity
Belongs to the 'GDXG' lipolytic enzyme family.
Sequence
MADPYEFLMCIHDPEEDTLTRNFPIPATPLDQNTKDISLNLDRKTSLRIFRPPTEEFCVTTNKLLPIIIYFHGGGFVLFNADSTINHDFCQSIATHLPALVVSVDYRLAPENRLPAAYDDAVDALNWVKDQGLGKLNNSEVWLKEYGDFSKCFIMGCSSGGNIAYHASLRAIEMDLEPVIINGLILHSPFFGSLQRTESDLKVINDQDLPLAVRDVMWELALPLGSSRDHVYCNPNIANDGSSSGNMAGLIKRCLVIGFYGDPLIDRQIQLVKMLEEKGVKVETWIEQEGYHGVPCFDPKIRETLLGKIKYFI