Protein
Modification methylase CviJI
Organism
Paramecium bursaria Chlorella virus IL3A
Function
This methylase recognizes the double-stranded sequence RGCY, causes specific methylation on C-3 on both strands, and protects the DNA from cleavage by the CviJI endonuclease.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Sequence
MSFRTLELFAGIAGISHGLRGISTPVAFVEINEDAQKFLKTKFSDASVFNDVTKFTKSDFPEDIDMITAGFPCTGFSIAGSRTGFEHKESGLFADVVRITEEYKPKIVFLENSHMLSHTYNLDVVVKKMDEIGYFCKWVTCRASIIGAHHQRHRWFCLAIRKDYEPEEIIVSVNATKFDWENNEPPCQVDNKSYENSTLVRLAGYSVVPDQIRYAFTGLFTGDFESSWKTTLTPGTIIGTEHKKMKGTYDKVINGYYENDVYYSFSRKEVHRAPLNISVKPRDIPEKHNGKTLVDREMIKKYWCTPCASYGTATAGCNVLTDRQSHALPTQVRFSYRGVCGRHLSGIWCAWLMGYDQEYLGYLVQYD