Protein
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2, chloroplastic
Organism
Chlamydomonas reinhardtii
Function
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
Similarity
Belongs to the AcsF family.
Sequence
MATMLNKRVTGAFGKQAPVRSARVAAVRPSRSSVRVAATAAPQEVEGFKVMRDGIKVASDETLLTPRFYTTDFDEMERLFSLELNKNMDMEEFEAMLNEFKLDYNQRHFVRNETFKEAAEKIQGPTRKIFIEFLERSCTAEFSGFLLYKELGRRLKATNPVVAEIFTLMSRDEARHAGFLNKAMSDFNLALDLGFLTKNRKYTFFKPKFIFYATYLSEKIGYWRYISIYRHLQRNPDNQLYPLFEYFENWCQDENRHGDFFTAVLKARPEMVNDWAAKLWSRFFCLSVYITMYLNDHQRDAFYSSLGLNTTQFNQHVIIETNKSTERIFPAVPDVENPEFFRRMDLLVKYNAQLVNIGSMNLPSPIKAIMKAPILERMVAEVFQVFIMTPKESGSYDLDANKTALVY