Protein
Protein COP1 SUPPRESSOR 2
Organism
Arabidopsis thaliana
Function
Inhibits E3 ubiquitin-protein ligase activity of COP1, a central repressor of seedling photomorphogenesis. Represses COP1-mediated turnover of HY5 in the dark. Required for primary root development under normal light growth conditions.
Similarity
Belongs to the TLS1 family.
Sequence
MPPKRNFRKRSFEEEEEDNDVNKAAISEEEEKRRLALEEVKFLQKLRERKLGIPALSSTAQSSIGKVKPVEKTETEGEKEELVLQDTFAQETAVLIEDPNMVKYIEQELAKKRGRNIDDAEEVENELKRVEDELYKIPDHLKVKKRSSEESSTQWTTGIAEVQLPIEYKLKNIEETEAAKKLLQERRLMGRPKSEFSIPSSYSADYFQRGKDYAEKLRREHPELYKDRGGPQADGEAAKPSTSSSTNNNADSGKSRQAATDQIMLERFRKRERNRVMRR