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CRH

Gene
CRH
Protein
Corticoliberin
Organism
Canis lupus familiaris
Length
196 amino acids
Function
Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).
Similarity
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Mass
21.547 kDa
Sequence
MRLPLLLSAGVLLVVSLPCPPCRALLSRGPIPGARQAAQHPQPLDFFQLPPQPQQPQQPQARPVLYRMGEEYFLRLGNLNKSPAAPLLPASSPVAGGSGSRLSPDEAAANFFRALLQQLPLPRRQLDSPAGPAERGEENALGSRQETPERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK

Gene
CRH
Protein
Corticoliberin
Organism
Homo sapiens
Length
196 amino acids
Function
Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).
Similarity
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Mass
21.422 kDa
Sequence
MRLPLLVSAGVLLVALLPCPPCRALLSRGPVPGARQAPQHPQPLDFFQPPPQSEQPQQPQARPVLLRMGEEYFLRLGNLNKSPAAPLSPASSLLAGGSGSRPSPEQATANFFRVLLQQLLLPRRSLDSPAALAERGARNALGGHQEAPERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK

Gene
CRH
Protein
Corticoliberin
Organism
Sus scrofa
Length
191 amino acids
Function
Hormone regulating the release of corticotropin from pituitary gland (PubMed:3878520). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).
Similarity
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Mass
20.997 kDa
Sequence
MRLPLLVSAGVLLVALLPCPPCRALLSRGPVLGARQAPQHPQALDFLQPQQQPQQPQPRPVLLRMGEEYFLRLGNLNKSPAAPLSPASSPLTGSSGNRPDEVAANFFRALLQQLPLPRRPLDSPSGPAERGAENALSSRQEAPERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK

Gene
CRH
Protein
Corticoliberin
Organism
Bos taurus
Length
190 amino acids
Function
Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).
Similarity
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Mass
20.777 kDa
Sequence
MRLRLLVSVGVLLVALLPSPPCRALLSRGPIPGARQASQHPQPLSFFQPPPQPQEPQALPTLLRVGEEYFLRLGNLDETRAAPLSPAASPLASRSSSRLSPDKVAANFFRALLQPRRPFDSPAGPAERGTENALGSRQEAPAARKRRSQEPPISLDLTFHLLREVLEMTKADQLAQQAHNNRKLLDIAGK

Gene
CRH
Protein
Corticoliberin
Organism
Ovis aries
Length
190 amino acids
Function
Hormone regulating the release of corticotropin from pituitary gland (PubMed:6267699, PubMed:6273874). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).
Similarity
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Mass
20.672 kDa
Sequence
MRLPLLVSVGVLLVALLPSPPCRALLSRGPIPGARQASQHPQPLSFFQPLPQPQEPQALPTLLRVGEEYFLRLGNLDETRAAPLSPAASPLASRSSSRLSPDKVAANFFRALLQPRRPLDSPAGPAKRGTENALGSRQEAPAARKRRSQEPPISLDLTFHLLREVLEMTKADQLAQQAHSNRKLLDIAGK

Gene
Crh
Protein
Corticoliberin
Organism
Mus musculus
Length
187 amino acids
Function
Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (PubMed:23470617).
Similarity
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Mass
20.778 kDa
Sequence
MRLRLLVSAGMLLVALSSCLPCRALLSRGSVPRAPRAPQPLNFLQPEQPQQPQPVLIRMGEEYFLRLGNLNRSPAARLSPNSTPLTAGRGSRPSHDQAAANFFRVLLQQLQMPQRSLDSRAEPAERGAEDALGGHQGALERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK

Gene
Crh
Protein
Corticoliberin
Organism
Rattus norvegicus
Length
187 amino acids
Function
Hormone regulating the release of corticotropin from pituitary gland (PubMed:6603620). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).
Similarity
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Mass
20.68 kDa
Sequence
MRLRLLVSAGMLLVALSPCLPCRALLSRGSVSGAPRAPQPLNFLQPEQPQQPQPILIRMGEEYFLRLGNLNRSPAARLSPNSTPLTAGRGSRPSHDQAAANFFRVLLQQLQMPQRPLDSSTELAERGAEDALGGHQGALERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK

Gene
crh
Protein
Corticoliberin
Organism
Carassius auratus
Length
162 amino acids
Function
This hormone from hypothalamus regulates the release of corticotropin from pituitary gland.
Similarity
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Mass
18.418 kDa
Sequence
MKLNFLVTTVALLVAFPPPYECRAIEGSSNQPATDPDGERQSPPVLARLGEEYFIRLGNRNQNYLRSPADSFPETSQYSKRALQLQLTQRLLEGKVGNIGRLDGNYALRALDSVERERRSEEPPISLDLTFHLLREVLEMARAEQMAQQAHSNRKMMEIFGK

Gene
crh
Protein
Corticoliberin
Organism
Xenopus laevis
Length
162 amino acids
Function
This hormone from hypothalamus regulates the release of corticotropin from pituitary gland.
Similarity
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Mass
17.88 kDa
Sequence
MKFQLWVSTGILLVSLLPCHECRAFIKSPASSPGALLPALSNSQPFLLRMGEEYFLRLGNLHKHSPGSFPEASAGNFVRAVQQLQAQQWSSQPGMRAASLDGADSPYSAQEDPTEKAKRAEEPPISLDLTFHLLREVLEMARAEQIAQQAHSNRKLMDIIGK

Gene
crh
Protein
HPr-like protein Crh
Organism
Bacillus subtilis (strain 168)
Length
85 amino acids
Function
Along with seryl-phosphorylated HPr, phosphorylated Crh is implicated in carbon catabolite repression (CCR) of levanase, inositol dehydrogenase, and beta-xylosidase. Exerts its effect on CCR by interacting with CcpA.
Similarity
Belongs to the HPr family.
Mass
9.327 kDa
Sequence
MVQQKVEVRLKTGLQARPAALFVQEANRFTSDVFLEKDGKKVNAKSIMGLMSLAVSTGTEVTLIAQGEDEQEALEKLAAYVQEEV

Gene
crh
Protein
HPr-like protein Crh
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Length
84 amino acids
Function
Involved in carbon catabolite repression (CCR).
Similarity
Belongs to the HPr family.
Mass
9.188 kDa
Sequence
MVEKQVEVKLKTGLQARPAALFVQEANRFTSEIFIEKDGKKVNAKSIMGLMSLAIGSGSTITLITEGNDEQEAMEALIAFIEKE