Cplane1

Ciliogenesis and planar polarity effector 1

3214 amino acids

Involved in ciliogenesis. Involved in the establishment of cell polarity required for directional cell migration (PubMed:25877302). Proposed to act in association with the CPLANE (ciliogenesis and planar polarity effectors) complex. Involved in recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).

358.55 kDa

MEMRLEVLTSTSIKQKKPWPRVSWLGQENEAVFLLDEKFINEINLLSGRTKKKIPSLQPLLKDVVFLATSTNDVWLSGVLTTGELFLWNKDQDCLKKIHVTEKPKEAIKAAVASSSRLYLYVAENGKRILLITSSGCILLWEYLELKNILSSKSLSLVGQWSQIVPEEAVSLPSTKDKEAVVAAVFVKNELLGDCCLCSFTFYSGECLKLTFLDIQWYENIFTSVRSLLFRVHWAQQECPLCSLIPRCASVKSRGALISAFSRDGLALAVTLNQKDPTATQVLFINTLNFVTLCGGLKGCSNKNPVVPATLTRSYWVGDISWTHDSLFLTCVLKRGSLVLLTCLGELLTLVTFGCSIEFGPAEFIPLHPLITYRPQQLPFQDSNNCVDSSASESDPLRQRFSIKAHSRLPYLIISDGYMVTTLRFLDNQSPTMLMRSLLLDSTQRLEKAYQSMMLSEPKDKGLNFRSLDSLRSSLLKHQGKESSVHCTVPRFLQAEETMKLNETTDFQDFEGEETNEVEQFVNNSFSFCNQKKDLPFDIVKEGRLEFASMFDTVHAKDASKETDRNTAELHRIQKTLLAAWTIGISKNVTEKKLMLNYTILCITHFFYILQFIKCPVPKFDLFLNKSLKRNAWVLCVFQLFHQCLSVHYWDMRYRQNMGHLIRLTANTVKLLLTQRQEHGSFSERLLACLSLLRTVTVHLNGTCSLQPEAVPAAADESRPAELDSLMVPIFQASKENWPWDSSLKIYPQVTNLVQKPGHRLIALWRLLYKKTLWYQAQLSQRTPDGDRRLTENIRHEVSVVKTLLCHVQTNLQMAGDSLNQALELTPISGEECFLLASYEKSVCLWKKALQETQEKGGRRTCFLQLRYYLSLLYCHLYCYNLNDAQGLCDHLVRELLSRSQLPVRESQDCSDCEIAVTGNVHPEAALRVVQCMARFMAAYFTNEPLFILPPHSVSVLPPLHVKTEHSLRLIPLQHSKVASVIRDQNLSNVWTVEYTLELLFIGGLIPEAVWMAHKLGDWKTSVSIGVAYQVFCKHDCNFARSKKKGMDLPLNMIPAQIFQEKLQCFLGQPVSLTKKNEKGSKYKQFTDPIEEEDASLLFGSVQEVLKASVMADADIVSETLQLLMDSAKDFSKKLWGLVPVDLYLPAPPLYCPQPAVLSEEHGDNLLLKAEKDNRQKLSGILQRVLLLFRASRCSFPVAQWYILQLRWARKVMQKIRVKGSLPSLGSFPESLLNYCKGGIAFFRPGATGDHTLDEVSIKALGCFRELCALCWMLHVRDKLSYTCRQYQKARENTKIEKDLEVGFDSCVVEHCFHALEWACRMLPFSRFFNMEELIQDIILSLIGELPPIRKVAEIFVKAFPNPEAIRVPLREKYHSLQQKLKHGVVKGPQTEELMSTVMRHVRKVRVKALKRVQRNIGAFEMDIWEPDEEDKPAATPAADRFSLGPSVSSTLTLDLGSSLLHSDADTFSETLSLEEKTWIHLYQRHTPSHMELALVGKKPSDKKKVSNQKENSQRKEDDETPGKEALPVIGVWEFERDDDEYISFLELFLSYILERDLCSSDPGIPFLTSFSGRLREHELNSLLFDVHTTLKRRQSKTISENVYRAGSCFAVTPESQEPENLSSLNSVGARHFESQALSASALGNQSGSTLENPLQSGSTSENPLQSDVMNWERRAGLFGLKQKPMYRVPDDKREKPTVQRSSNHSFWVPESIKPGRHRFRALEGSAGPPREDLPLALQSMFGDAGRLVEWMIRWSDRRLLCDPGVTPSSCKYSPVIRVKTSTAAILTSLWLLEQPYSAAYTAKNGIIKVLERHHTEPQVAAERESDVDADCPAAVAAQEGTECWNRMPAEAENHDVKDTGDEIAPVTPGSERELVHADGRHSEAGSSTQDEMDVHISDSEEGPVESLRGPSAVICRPESQLSSEHSEEEAQCSRKEPRDASVDTNLTEQKGAQISDLKEKSPTVLPLMSNGAQDTSQTPQKTQGNEHRAQLPDASESVRQMLQDEMFKLVQLQQINFLSLMQIVGPSVASLPDMHGLLQQAQSVRFGESQVSNSTKSDCIEVNSRQRVSARAQSMGECTREPGKNSPADHKRISRPDQDSSGDTQDIPHGSVPLCQLDGQPEVRGQTGAPRSFAPASFPPAPAADSGLQLLFTPAAIQKTPQLIPPARAGAPGRGFPLLHFQPKRDFKPLSLPVGRIPQVSFRPQAQPKEAWSLSDSCQPPVSQRTVHTTLPSPSDSSHCNAEAMRKAEAVLTGIPKHVNMGQYAGQGYLTPQQDSSVFIKPENVFDVKPSPPETALQNSFGLPLLHLQFKPPYVFSAPPRAFSRFPSVPGTEGRNQPQLSLLHPCLPPENTYKKPQLIPLENLLAFKRSQQKLAHSVSGQGDAAPHFVGVSMDAAGITQGKQRQSRRAKRELQEGRAQKPRRKPNVSFRPEDSLISNDSEVIIEPKEQLGHHDSQHLDKFDIPFEMLEDDINTSAGLHFMASVRKKAVGSHDASTNTDPDKEGPSQKADSESSKNPQATAASSGHEPLKVPQLLIPDIYLNVRLPSGIAEKPLSPSPPHMAGHKYIDVVDIEADDLLGLPACEEPSDEVTKQQSHPPHAPSSAELHCMAASIVDAAPPHTFQSQESASSTRGLISEPAKVTQSCQSGESWRKSVIEAKEPEIPSVAPPSDRQQDRDILEQNFQFKEQSTKLDSVGQSLLWTLLQNASPACPTPSPAVCPRPSSPACPPPSPAVCPPPSPAACPTPSPAAQKFEHLTAKLQEMDEQLVAVQTMAENIEQDFPASQVLNLHWEKAGLGNHVGLSSGPDIEKLLASKAISISEEVSLQTQEDVEEQKDAEETSETEFSEAENHSSQKTYACPSVGSAACSSVGWNIPSPGLNDSNELLESGSEDQLQVTGLTDIADIIGDLITKSGVSSHELGLTECQARSISRIQRPPDRGPRRTAEERREIKAWMRRKQKERMSEYLGQLAERRGRERNPFCPTSSPFYMTSRQIRQRQKMKREKDRLQLSKHYSQRLSQAYSLMNELLSDSAHITAPAENPLPPGPYRRQRGSSPKRENAHGQSLPVNRPGGDRHISRSSHLCKGQPRGSSQLRGSQPPCQSQKPLRSRGAAGVGPPVQQACREDEREEMVVSPWTLPSEIHRILHGRPESLLQDMSPADEEEPEPPLLAGGMDSVSESTGSILSKLDWKAVEDMVASVEDKNLSVHWALDQ

CPLANE1

Ciliogenesis and planar polarity effector 1

3197 amino acids

Involved in ciliogenesis (PubMed:25877302). Involved in the establishment of cell polarity required for directional cell migration. Proposed to act in association with the CPLANE (ciliogenesis and planar polarity effectors) complex. Involved in recruitment of peripheral IFT-A proteins to basal bodies (By similarity).

361.746 kDa

MEIRLEILTSTGIKQKKPWPRVSWLGKEKEAVFLLDDKFINEINLLSGKIKKKIPSLQPFLKDVIVLTTSSNDAWLAGVLTTGELFLWNKDQDCLKTIPITEKPKEMIKATVASSLRLYLYVSGNGKRIVLITPSGCIFLWEYLELKNILSSKSLSLAGRWSQVIPEEAVLLPSTEDKEAVVNAVFIKNELFGDCCLCSFTFYSGECLKLTFLAIRWHENVFTSVRSLPYHVHWAQQDCHLCSLIPKCESVKSRGALISAFSRDGLTLAVTLNQKDPKATQVLFINTLNFVTLCGSLKGCSNKSPVVPATLIRSYWVGDISWTHDSLFLACMLKRGSLVLLTCQGELLTLITFGCSIEFGPAEFIPLHPLITYRPQQFTFQDSNNSVDSSASDSDPMRQRFSIKAHSRLPYLVISDGYMVTTLRFLDSLSPSVHMRSLLLDSTQRLEKIYQSVILSKPKGKGLNLRSLNSLRSSLLEHQGNESSADFTVPKFLQAEETINENAADFQDFEAEETNEGRHFPDNLCPFWNKRDDVLCSSMKEGRLEFASMFDTIHAKDDSEETDRTITELHSIQKSLLAAWTIGISKTVTEKNLMLNYIVVCITHFFYILQFIKCPFPKLDLVLSKSSRHNAWILCIFQLFHQCLSIHYWDIRYKQDVGHLIKLTSNTVKLLLTQQQKGQLFSEKLLACFYLLKMVADNLNGVYILQPEVISASADGSKITAQDSLVVPIFQMFQDSGFQKNWSWNSFFKIHPQVVNPVQQPGHRLLILWRILYKKTLWYQAQLNRRVPEADSQLTEKMTHEASTVKSLLCHLQANLQSTGDCLNQTLELKSINGEECFLLGSYEKSVQLWKKALQEIEEKGGRRTYFLQIRYYLSLLYCHLYSYNLNDAQGLCDQLAREILRWSQLPVKENKDFSGAAKSHFECGMVGGVHPEAAVRVVQSMARFMAAYFTNQQLCILPPHHVNVLPPLHIKTEQSFRLIPLQHSKVASVVRDQNLSNVWTVEYALELLFIGGLVPEAVWLAYKLGDWKTSVSIGVAFQLFCKRDSNFMRSKKKSLNLPLRMTPAQIFQEKLQCVLGQPASLEAKNEMGSKYKQFTDPIEEEDANLLFGSVQEVLKASVMADADILSETFQLLIDSAKDFSKRLWGLVPFGLYLPAPPLYCPQPAILSEEDGDDLLLKAEKNNRQKVSGILQRVLLLFRAAQCSFPVAQWYILQLRWARKVMQKIRMKGSLPSLSPFPQSLLNYCKGGIAFFRPGAAGDHKLDEVSIRAIGCFRELCALCWMLHVRDKLSYSCRQYQKARENVKGEKDLEVEFDSCMIEHCLSAVEWAYRMLPFSRFFNMEELIQDIILSLIGELPPIRKVAEIFVKAFPYPEDVRVPLRDKYHSLHQRLRHCVVKGPQTEEMMSVVMHSIQKVRVKALKRVQRNIGSFEVNIWEPIEEEKPDEAPGVDRYSLGTSLSRSTLTELGDSVVHSDADTFSEALSVEEKSRINIYQRNAPNHMELTSIHKPTDKRKMCNQKENPTKKEDHEKLSQNTLPVIGVWEFERDDDEYIKFLDLFLSYILERDLPYSRDADIPFLTSFSGKLREHELNSLLFDVHTTLKRHQSKTKSQNVFRAGSCFVVAPESYESEKSSSLNDEYGMHLENQKLSSSVLVNQGIKPFLQYPSNEVNKNEGMSGLFGLKQRSIYKIQDDTREKCLIQRSSNHIFWTPKSIKTRRCIFKAIQCNDINPQEDLPLALNTFGSIGRLLEWMIRWSNRRLLCDSGITESSSEYSPVIRVKTSTAAILTSLWLLEQPYFATYKAKNAIIKMVENRDTGCQIGPNIERESKSDAGGSVAVATPGGTEERNGQNKSCQNILNRMPTEAKNPDIKEINDDIISITHNTKKEFIDIDENLLEVEAFTEEEMDMHISDYEEDIEESVGGFRSPSLAICMMTLPQQLEEEFTEEVQCQREEPLETIMEEKSTEQKGMIEAFSHPGHTTPQSMQVDTSSEISSAQISTYKEKSSSVPLLISNGVNVASQPPAPTPQKTQRNEFTAQLPDCSESVRQMLQDEMFKLVQLQQINFMSLMQIVGSSFANLPDTQQLVQQSQSVHLGESQESNLRGCGDVEDSNKNLKERFFIKPQSMGENAREPRKNSPHCHEGTIPSGQNSTGNVQNVPHGSIPLCQLNGQPRKKGPIPSSQNLPSTSFYPAPAGNTHLYLLSTPSVVQKAPRLIPHAKTFSPGDGFPLLQFKSKQEFQPLFLHTGSIPQVPFRPLPQPREAWGLSDSFQPALPQRAAQTTPASHLNVSQYNTEARKKEVEQKTWAETVITEIPNHVNLDQYVGQENLTPQQDSSVFIKPEKLFDVKPGTLEISPHHSFGLPLLYLPLKPPNMFPSTSRASITVPSTPIQPIAEERKYPRLSLLHSHLSPENRCKKTQLIPLENLIAFKQSQQKLTHNLFEQGDAGHLQLLKVKIEPPEVRQGKDSKKRQRRRAEKELQEKRCEKLRRKPNVTFRPENSIINNDDSEIIKKPKEQQEHCGSHPLDDFDVPFEMLQDDNTSAGLHFMASVKKKAIGSQDASTNTDPEHEPLTAPQLLVPDVYLNLKLSSEMSEKPWSPSIPHTVTNLELPVREEPSNDNVIKQQSDHLAVPSSAELHYMAASVTNAVPPHNFKSQGLPKPEFRFKGQSTKSDSAEDYLLWKRLQGVSAACPAPSSAAHQLEHLSAKLQKIDEQLLAIQNIAENIEQDFPKPEMLDLHCDKIGPVDHIEFSSGPEFKKTLASKTISISEEVRFLTHMDEEDQSDKKETSEPEFSITENYSGQKTCVFPTADSAVSLSSSSDQNTTSPGMNSSDELCESVSVHPLQMTGLTDIADIIDDLIIKDGVSSEELGLTEQAMGTSRIQHYSGRHSQRTDKERREIQAWMKRKRKERMAKYLNELAEKRGQEHDPFCPRSNPLYMTSREIRLRQKMKHEKDRLLLSEHYSRRISQAYGLMNELLSESVQLPTLPQKPLPNKPSPTQSSSCQHCPSPRGENQHGHSFLINRPGKVKYMSKPSYIHKRKSFGQPQGSPWPHGTATFTIQKKAGGAKAAVRKATQSPVTFQKGSNAPCHSLQHTKKHGSAGLAPQTKQVCVEYEREETVVSPWTIPSEIHKILHESHNSLLQDLSPTEEEEPEHPFGVGGVDSVSESTGSILSKLDWNAIEDMVASVEDQGLSVHWALDL