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COQ3

Gene
COQ3
Protein
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Organism
Bos taurus
Length
370 amino acids
Function
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
Mass
41.49 kDa
Sequence
MWGGSKLSSSGSRFLGALRSGFQSTQVDSSRLTTSAVYPKNQLSWILQIKPWVFNENRIMWFKSYSITFACLNWMKSYRLPWTRPYSTSRTTVDKNEMKTFLALAHRWWDEQGVYAPLHSMNDLRVPFIRDNLLRTVATHQPGKPLSGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQHHKSFDPVLDKRIEYRTCSLEEIVKDTVETFDAVVASEVVEHVIDLETFIQCCFQVLKPDGSLFITTINKTQLSYALGIVFSEQIAGIVPKGTHTWEKFVSPEKLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAHALKSSLQEQPAPAEFALKGEAEELQAEASTNSGVQEDLKK

Gene
Coq3
Protein
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Organism
Mus musculus
Length
370 amino acids
Function
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
Mass
40.957 kDa
Sequence
MWRGGRLGSRGVRLLETLGFGCPSAVAQPPRLTSRSAYSGTQLTRNLQIKPWELGEHGTMCFRSYRMALSCLSRVKTYRTPWKRLYSTSQTTVDSREVKNFQALAHTWWDEYGKFAPLHSMNDLRVPFIRDNLLKTSASHHPGKPLSGMKILDVGCGGGLLTEPLGRLGASVVGIDPVAENIKIAQHHKSFDPVLDKRIQYKVCSLEEAVDESAECFDAVVASEVVEHVSHLEMFIQCCYQVLKPGGSLFITTVNKTQLSYALGIVFAEQIAGIVPKGTHTWEKFVSPEKLESILEPNGLSVETVAGLVYNPFSGYWHWSENTSLNYAAHAVRSRAQEHQEPAESALKGETGALHANTSGSPSVREEQRT

Gene
COQ3
Protein
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Organism
Homo sapiens
Length
369 amino acids
Function
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
Mass
41.054 kDa
Sequence
MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIWFKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQIASIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAYAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK

Gene
Coq3
Protein
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Organism
Rattus norvegicus
Length
345 amino acids
Function
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
Mass
38.708 kDa
Sequence
MWRGGRLSSRGVRFLETLGFACPSAVAEPPRVTSWTAFSGNQLTRNLQIKPWEFSGHRTMWLRSYRITFSCLTRLKTYRSSWKKLYSTSQTVDSKEVKTFQALAHSWWDEQGKFAPLHSMNDLRVPFIRDNLLKTSTNHDPGKPLSGMKILDVGCGGGLLTEPLGRLGASVVGIDPVAENIKIAQHHKSFDPVLDKRIQYRVCSLEETLNENAECFDAVVASEVVEHVNNLEMFIQCCYQVLKPGGSLFITTVNKTQLSYVLGIVFSEQIAGIVPKGTHTWEKFVSPEKLESILEPNGLSVETVAGMVYNPFSGYWHWTENTSLNYAAHAVRARAQEHLEPAESA

Gene
COQ3
Protein
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Organism
Candida albicans
Length
327 amino acids
Function
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
Mass
37.561 kDa
Sequence
MMVFLVSFISVEMKSMHCAPLFRQLVFSRSLHYSKTIFHNGRGLTSTSESEMSHFNALASSWWDVNGPQRILHKMNLLRMDFIHDTIRKNLKLNENTDDEVYIPPFSVDLLPQGIKNKIDEDQEMRRDEILNDSSLTVLDVGCGGGILSESMARLSFVSSVKGIDLSADVLEAAKLHKQKDPMLKDKLSYTLNAIEDIPETERFDIVTMFEVLEHVDYPSRVLLEGLKRLESGGWLFLSTINRDFVSWFTTIFMGEHVLRIVPVGTHTLEKYINQSEIKDWLQEDSNRKSEFRVADTKGCVYLPAYGWKFTSCPDVGNYFMAIQRVK

Gene
COQ3
Protein
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Organism
Arabidopsis thaliana
Length
322 amino acids
Function
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
Mass
35.332 kDa
Sequence
MLASVRVNQLQRLLLSARRLSSSPIIPPSRLLHQRLFSTSDTDASAASFSSSHPKIQTLEGKASNKSRSTSSTTSLNEDELAKFSAIADTWWHSEGPFKPLHQMNPTRLAFIRSTLCRHFSKDPSSAKPFEGLKFIDIGCGGGLLSEPLARMGATVTGVDAVDKNVKIARLHADMDPVTSTIEYLCTTAEKLADEGRKFDAVLSLEVIEHVANPAEFCKSLSALTIPNGATVLSTINRTMRAYASTIVGAEYILRWLPKGTHQWSSFVTPEEMSMILQRASVDVKEIAGFVYNPITGRWLLSDDISVNYIAYGTKRKDLGDI

Gene
coq3
Protein
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Organism
Dictyostelium discoideum
Length
321 amino acids
Function
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
Mass
36.538 kDa
Sequence
MIYHLISKSCQRLNKPNLINNLIKSQKQSIIYSSSSSSGSSKFISNKYFTTTSNSNNNSNNTTTTTTTTLRQDEIDFFNQQSSDWWNPEGTMKPLHRMNPFRVKYICDRLKIYNEKVSKNPIHLPLEGLNVIDVGCGVGLLTESLSRLGASKVVGLDAAKNNILMAISHASFDQKLNENIQNKSLNYLESTIENFYNIENDQQFDAVCSLEVIEHVDNPKQFIDYLSKIVKPGGSIFISTINKTFLSYISAILGAEYIFRMVPVGTHHWDQFIKPKDLESYFDSNNCQITDLKGLVYNPLTCEWDFTNDLNVNYLLHAIKK

Gene
COQ3
Protein
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
312 amino acids
Function
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. Catalyzes the methylation of 3,4-dihydroxy-5-hexaprenylbenzoate (DHHB) to 3-methoxy-4-hydroxy-5-hexaprenylbenzoate (HMHB) and the methylation of 2-hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol (3-demethylubiquinol-6) to ubiquinol-6.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
Mass
36.331 kDa
Sequence
MLLRSRFLKVIHVRKQLSACSRFAIQTQTRCKSTDASEDEVKHFQELAPTWWDTDGSQRILHKMNLTRLDFVQRTVRNQVKIQNPEIFVPGFNYKEFLPEYVCDNIQREMQESIETNLDKRPEVSVLDVGCGGGILSESLARLKWVKNVQGIDLTRDCIMVAKEHAKKDPMLEGKINYECKALEDVTGQFDIITCMEMLEHVDMPSEILRHCWSRLNPEKGILFLSTINRDLISWFTTIFMGENVLKIVPKGTHHLSKYINSKEILAWFNDNYSGQFRLLDLKGTMYLPYQGWVEHDCSDVGNYFMAIQRLN

Gene
coq3
Protein
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
274 amino acids
Function
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
Mass
30.827 kDa
Sequence
MNSMNILNKVKNVKSYTRLVRQGFLSQQRNHSVSVNEVDHFNELAKTWWDWDGGSRLLHLMNSTRLDFMTEVFRERNCFSGKKILDIGCGGGILSESMARLGASVTAVDASPMAIEVAKKHASLDPVLNGRLEYIHGSVEGSQLPTTFDVVTCMEVLEHVEQPRDFLFSLMEKVKPNGRLVLSTISRTLLARLLTITLAEHVLRIVPVGTHTFEKFIRADELSNFLKEQNWIINDIRGVCYNPLKQQWTLDKPGSSGLGLSCNYFLSAQKPMSA