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CNMD

Gene
CNMD
Protein
Leukocyte cell-derived chemotaxin 1
Organism
Gallus gallus
Length
347 amino acids
Function
Bifunctional growth regulator. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization (By similarity).
Similarity
Belongs to the chondromodulin-1 family.
Mass
38.636 kDa
Sequence
MAEGSEKVPIARAGPEDVEQGLPPAYTAAVPPPGPGRLLKAGATVLIAGALLLLAGAIGAFYFWKATERQVYNVHYTMSINGKVQDGSMEIDAGNNLETFKTGSGSEEAVEVHDFQIGITGIRFAGGEKCYIKAQPKARVPEVDAMTKASLSSDLEDEIMPVRFDENSLIWVAADEPIKHNGFLSPKILELCGDLPIFWLRPTYPKDKQRERREMKRNKRQSESNFDAEHRAAAAEEVNTRSTPTQLTQDLGPQSNETRPMQQESDQTLNPDNPYNQLEGEGMAFDPMLDHLGVCCIECRRSYTQCQRICEPLLGYYPWPYNYQGCRTACRIIMPCSWWVARIMGVV

Gene
CNMD
Protein
Leukocyte cell-derived chemotaxin 1
Organism
Bos taurus
Length
335 amino acids
Function
Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization (By similarity).
Similarity
Belongs to the chondromodulin-1 family.
Mass
37.164 kDa
Sequence
MTENSDKVPIALVGPDDVEFCSPPAYAAVTVKPSSPARLLKVGAVVLISGAVLLLLGAIGAFYFWKGSDNHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAVEVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGTMTKQSISSELEGKIMPVKYEENSLIWVAGDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERRELVRKIVTTTTTRRLRSGPQGTPAPGRPNNGTRPSVQEDAEPFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYHPWPYNYQGCRSACRVIMPCSWWVARILGMV

Gene
CNMD
Protein
Leukocyte cell-derived chemotaxin 1
Organism
Homo sapiens
Length
334 amino acids
Function
Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
Similarity
Belongs to the chondromodulin-1 family.
Mass
37.102 kDa
Sequence
MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Gene
Cnmd
Protein
Leukocyte cell-derived chemotaxin 1
Organism
Mus musculus
Length
334 amino acids
Function
Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development (By similarity). Inhibits in vitro tube formation and mobilization of endothelial cells (By similarity). Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
Similarity
Belongs to the chondromodulin-1 family.
Mass
37.225 kDa
Sequence
MTENSDKVPITMVGPEDVEFCSPPAYTTVTVKPSGSPTRLLKVGAVVLISGAVLLLFGAIGAFYFWKGNDNHIYNVHYSMSINGKLQDGSMEIDAVNNLETFKMGSGAEEAIEVNDFKNGITGIRFAGGEKCYIKAQVKARIPEVGTVTKQSISELEGKIMPANYEENSLIWVAVDQPVKDSSFLSSKILELCGDLPIFWLKPMYPKEIQRERREVVRNSAPSTTRRPHSEPRGNAGPGRLSNGTRPNVQDDAEPFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVVMPCSWWVARILGMV

Gene
Cnmd
Protein
Leukocyte cell-derived chemotaxin 1
Organism
Rattus norvegicus
Length
334 amino acids
Function
Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization (By similarity).
Similarity
Belongs to the chondromodulin-1 family.
Mass
37.387 kDa
Sequence
MTENSDKVPITMVGPEDVEFCSPPAYATVTVKPSGSPTRLLKVGAVVLISGAVLLLFGAIGAFYFWKGNDNHIYNVHYTMSINGRLQDASMEIDAANNLETFKMGSGAEEAIEVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVSTGTKQSISELEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKILEFCGDLPIFWLKPMYPKEIPRERREVVRSSAPSTTRRPHSEPRGNAGPGRLSNRTRPSVQDDEEPFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVVMPCSWWVARILGMV

Gene
CNMD
Protein
Leukocyte cell-derived chemotaxin 1
Organism
Oryctolagus cuniculus
Length
333 amino acids
Function
Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization (By similarity).
Similarity
Belongs to the chondromodulin-1 family.
Mass
36.974 kDa
Sequence
MTENSDKVPIALVGPDDVEFCGPPAYATVTVKPSGPARLLKVGAVVLISGAVLLLFGAIGAFYLWKGSDNHIYNVHYTMSINGKLQDGSMEIDARNNLETFKMGSGAEEAIEVNDFQNGITGIRFAGGEKCYIKAQVKARVPEVGTVTQQSISSELEGKIMPVKHEEEALVWVAVGQPVQDNSFLSARVLELCGDLPIFWLKPTYPKEIQRERREVVRKTVPTTTKRPHSGPRGNPGPARMRNDSRPSVQEDSEPFNPDNPYHQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYNPWPYNYQGCRSACRVVMPCSWWVARILGMV

Gene
cnmd
Protein
Leukocyte cell-derived chemotaxin 1
Organism
Danio rerio
Length
286 amino acids
Function
Bifunctional growth regulator. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization (By similarity).
Similarity
Belongs to the chondromodulin-1 family.
Mass
32.235 kDa
Sequence
MEETAEKTPVEAYSTLKPKGLMKMKKTALVAFIAGAALLLFGGVGAFYLWKVTEKEAISAHLGRNIDIKIENDSDSAEGTIVEVQDFKAGITAVKFPGKEKCFIKSQARTELSEDEAGVKAEVASLVWITSEEPLKDSSFLSPEILRFCADLPIYWHHPANSRALRKRRSATRMRRQTSAGVNRQPARRRNSTASARDERPTGPEYNPENPYHQNQGSEGTMVFDPMLDHRGICCTECHRSYTHCERVCEPLGGYWPWPYNYHGCRPVCRLIMPCRWWAARVLGLV