CMT3

DNA (cytosine-5)-methyltransferase CMT3

907 amino acids

Involved in CpXpG DNA methylation. Plays a critical role in the maintenance of CpXpG DNA methylation and suppression of a wide spectrum of transposable element (TE) activities. Required for proper plant development in reproductive stage.

Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

101.415 kDa

MAPSSPSSAAAPTRTSTRKRAASASASAKATDEPSTKRTRRPKAETKPRKKKDEVKEEEKPPMEDDACGEEPDAEEMALGEEAEAEEAEAEQKQLDAPAPGVARKRVAQPSRVRHGSDGDHDPEFVGDPFPAKEARDKWPQRYQRNAATRRPDEEEDIKARCHYSSAKVDGTLYCLHDDVYVKAEEDKADYIGRITEFFEGTDHCHYFTCRWFFRAEDTVISSIMMENADDEKHDLKRVFLSEEKNDNVLDCIISKVKIVYIDPNMESEAKARRLADCDLYYDMSYTVAYSTFANIPLENGASGSDTASDISSDDVDSSKGKVVSDSEASSVGKATLLDLYSGCGGMSTGLCLGAALAGLNLETRWAVDFNSFACESLKYNHPRTEVRNEKADEFLALLKGWHSLCDEYVKKDIDFSSAGASENEEDDDEPLEKDEFVVEKLAGICYGGSGREDGLYFKVQWKGYGREEDTWEPIENLRDCPLKIKEFVQEGYRRKILPLPGDVDVICGGPPCQGISGFNRFRNRKEPLKDEKNKQMVTFMDIVAYLKPKYVLMENVVDILKFADGYLGRYALSRLVAMKYQARLGMMVAGCYGLPQFRMRVFLWGALPTMVLPKYPLPTHNVVVRGGAPNAFSQSIVAYDETQKPTLKNALLLGDAISDLPEVNNHQPNEVMEYGSSPKTEFQRYIRLSRKEMLDSSFEGKDGPDLGKLLDHQPLKLNKDDHERVQQIPVKKGANFRDLKGVRVGANNIVEWDPDVPRVYLSSGKPLVPDYAMSFIKGRSLKPFGRLWWDETVPTVVTRAEPHNQIILHPNQARVLTVRENARLQGFPDYYKMFGPIKEKYIQVGNAVAVPVARALGYSLGLAYQRESEGSSPLFVLPDSFTEVGRQAAPARASSVGIPVGEVVEQ

CMT3

DNA (cytosine-5)-methyltransferase CMT3

839 amino acids

Involved in the CpXpG methylation and in gene silencing. Methylates preferentially transposon-related sequences. Functionally redundant to DRM1/DRM2 to maintain non-CpG methylation. Involved in RNA-directed DNA methylation.

Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

94.905 kDa

MAPKRKRPATKDDTTKSIPKPKKRAPKRAKTVKEEPVTVVEEGEKHVARFLDEPIPESEAKSTWPDRYKPIEVQPPKASSRKKTKDDEKVEIIRARCHYRRAIVDERQIYELNDDAYVQSGEGKDPFICKIIEMFEGANGKLYFTARWFYRPSDTVMKEFEILIKKKRVFFSEIQDTNELGLLEKKLNILMIPLNENTKETIPATENCDFFCDMNYFLPYDTFEAIQQETMMAISESSTISSDTDIREGAAAISEIGECSQETEGHKKATLLDLYSGCGAMSTGLCMGAQLSGLNLVTKWAVDMNAHACKSLQHNHPETNVRNMTAEDFLFLLKEWEKLCIHFSLRNSPNSEEYANLHGLNNVEDNEDVSEESENEDDGEVFTVDKIVGISFGVPKKLLKRGLYLKVRWLNYDDSHDTWEPIEGLSNCRGKIEEFVKLGYKSGILPLPGGVDVVCGGPPCQGISGHNRFRNLLDPLEDQKNKQLLVYMNIVEYLKPKFVLMENVVDMLKMAKGYLARFAVGRLLQMNYQVRNGMMAAGAYGLAQFRLRFFLWGALPSEIIPQFPLPTHDLVHRGNIVKEFQGNIVAYDEGHTVKLADKLLLKDVISDLPAVANSEKRDEITYDKDPTTPFQKFIRLRKDEASGSQSKSKSKKHVLYDHHPLNLNINDYERVCQVPKRKGANFRDFPGVIVGPGNVVKLEEGKERVKLESGKTLVPDYALTYVDGKSCKPFGRLWWDEIVPTVVTRAEPHNQVIIHPEQNRVLSIRENARLQGFPDDYKLFGPPKQKYIQVGNAVAVPVAKALGYALGTAFQGLAVGKDPLLTLPEGFAFMKPTLPSELA