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CLS

Gene
CLS
Protein
Copal-8-ol diphosphate hydratase, chloroplastic
Organism
Cistus creticus subsp. creticus
Length
808 amino acids
Function
Involved in the biosynthesis of oxygen-containing labdane-type diterpenes that may be implicated in direct and indirect defense mechanisms. No activity with geranyl diphosphate or farnesyl diphosphate as substrate.
Similarity
Belongs to the terpene synthase family.
Mass
92.655 kDa
Sequence
MAFTFTSAHLFLPVTENHSVHVNYSIPPGNWRLWSTAKGGSNKLDIRRLRCSARRTPEPLAQGSNGGRDGVEAIQRLQTIADDKIDGGANELGIVVWDLIRDGVDAVKSMFDSMGDGDISISAYDTAWVALVKDVNGSGGPQFPSSLQWIVDNQLPDGSWGDSEVFSAYDRLLKTLACVVALKSWNIRPDKCQKGLKFFRDNISKLEKENVEASAQMLSGFEVVFLSLIEVARRLDIQIPLHSPVFEDLIARRNLKFAKIPLDLMHNVPTSLLNSLEGMTGVELDWEKLLKLQSQDGSFITSPSSTAFALMQTNDTKCLGYLKFVVQKFNGGAPGQYPVEIFERIWVVDRLQRLGISRYFQLEIKECCLDYAFKHWTQYGSSWARNTPVYDLDDTCMAFRILRLHGYDVSAEAFRHFEKNGVFFCFGWETTQSVTVNFNLYRATQVAFPGENILKEAKQFSFNFLMKKQAAREFQDKWVILKDFPGELKYALEFPWYASLPRVETRFYVEQYGGDNDVWIGKTLYRMPYINNNVYLELAKLDFNNCQALHRKEWETMQKWFMESKLDEFGVSSKTLLESYFLAAASIFEPERSTERLAWAKTAFLMETIGSYFDDEMNSKDLRKAFVQEFKNIYERRMEAKGTKWNLIIILLTTLNHLTEVCGRDINSYLCHSWEKWMMMWEPEGDRYKGAAELLSNSINLSSGRLFSNDTLSHPNYEKLVTLSNKLCHQLGNSRRGNHNEDSDIKDTKIEIAMQELVQLVHQNSSDDISMDLKQTFFAVVRSFYYAAHCDRGTINSHIVKVLFESVV

Gene
CLS
Protein
Copal-8-ol diphosphate hydratase, chloroplastic
Organism
Cistus creticus subsp. creticus
Length
808 amino acids
Function
Involved in the biosynthesis of oxygen-containing labdane-type diterpenes that may be implicated in direct and indirect defense mechanisms. No activity with geranyl diphosphate or farnesyl diphosphate as substrate.
Similarity
Belongs to the terpene synthase family.
Mass
92.655 kDa
Sequence
MAFTFTSAHLFLPVTENHSVHVNYSIPPGNWRLWSTAKGGSNKLDIRRLRCSARRTPEPLAQGSNGGRDGVEAIQRLQTIADDKIDGGANELGIVVWDLIRDGVDAVKSMFDSMGDGDISISAYDTAWVALVKDVNGSGGPQFPSSLQWIVDNQLPDGSWGDSEVFSAYDRLLKTLACVVALKSWNIRPDKCQKGLKFFRDNISKLEKENVEASAQMLSGFEVVFLSLIEVARRLDIQIPLHSPVFEDLIARRNLKFAKIPLDLMHNVPTSLLNSLEGMTGVELDWEKLLKLQSQDGSFITSPSSTAFALMQTNDTKCLGYLKFVVQKFNGGAPGQYPVEIFERIWVVDRLQRLGISRYFQLEIKECCLDYAFKHWTQYGSSWARNTPVYDLDDTCMAFRILRLHGYDVSAEAFRHFEKNGVFFCFGWETTQSVTVNFNLYRATQVAFPGENILKEAKQFSFNFLMKKQAAREFQDKWVILKDFPGELKYALEFPWYASLPRVETRFYVEQYGGDNDVWIGKTLYRMPYINNNVYLELAKLDFNNCQALHRKEWETMQKWFMESKLDEFGVSSKTLLESYFLAAASIFEPERSTERLAWAKTAFLMETIGSYFDDEMNSKDLRKAFVQEFKNIYERRMEAKGTKWNLIIILLTTLNHLTEVCGRDINSYLCHSWEKWMMMWEPEGDRYKGAAELLSNSINLSSGRLFSNDTLSHPNYEKLVTLSNKLCHQLGNSRRGNHNEDSDIKDTKIEIAMQELVQLVHQNSSDDISMDLKQTFFAVVRSFYYAAHCDRGTINSHIVKVLFESVV

Gene
cls
Protein
Cardiolipin synthase
Organism
Geobacillus kaustophilus (strain HTA426)
Length
502 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
57.433 kDa
Sequence
MRNTSRVAILVVIVGALLALTNGFWEGKLLGLFSVLMSCSVIFIALVISLENRKPAQTIAWLAVLGSFPIVGFLFYLLFGRNYWQQRRYKKKADFDEAVLLKFQEPSPIAVERLPMAPHQRPLLRLAYRIGQHPVSLASQTAVLTNGEETFSSIFAELEKAEHHIHLEYYIVRHDEIGQQLKRVLMEKARQGVRVRFLYDAVGSWKLSNAYIEELRAAGVEMIPFSPVRLPFLSNQINFRNHRKIIVIDGGVGFVGGLNIGDEYLGKNKYFGFWRDTHLLIRGEAVRTLQLIFLQDWYYMTGERLLTPDYLSPPLIVEEGQGGVQLIAGGPDQKWEVIKQLYFAMITSAKRSIWVASPYFVPDEDILTALKVAALSGIDVRLLAPKRPDKKIVFYASRSYFPELLEAGVKIYEYEKGFLHSKVIVVDGELASIGTANMDMRSFHLNFEVNAFLYYTDSIHKLVRDFLEDFRHASMIDYEQFQQRPFRVRIAESVSRLLSPLL

Gene
cls
Protein
Cardiolipin synthase
Organism
Geobacillus sp. (strain WCH70)
Length
502 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
57.736 kDa
Sequence
MRNTLRVIIFVLAVAAFLFLTNDYWEGKLLGGLSILISCSVVFIAFVISLENRKPAHTITWLVVLGSFPLIGFFFYLMFGRNYRKQRLFQKKAMLDEQTFLKFQGQREWAIEQMPIGEHQRPLLQLAHRIGKSPVSLATETRVLTNGEETFSTIFEELEKATHHIHLEYYIVRHDEVGQKLKTILIEKAKKGVHVRFLYDAVGSWKLSKTYIQELRDAGVEMIPFSPVRLPFLSNTINFRNHRKIIVIDGTIGFVGGLNIGDEYLGKDKYFGFWRDTHLWIRGEAVRTLQLIFLQDWYYMTGKTLLTPEYLSPELVHYDGQGGVQLIAGGPDQKWEVIKHLYFAMITSAQRSIWIASPYFVPDEDILTALKIAALSGLDVRILAPKRPDKKIVFYASRSYFPELLEAGVKIYEYSKGFLHSKIMIVDGELASIGTANMDMRSFHLNFEVNAFLYHTDSTKKLVADFLEDLKEASPIDYETFQQRPLSIRVVESVSRLLSPLL

Gene
cls
Protein
Cardiolipin synthase
Organism
Geobacillus thermodenitrificans (strain NG80-2)
Length
502 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
57.336 kDa
Sequence
MRNTSRVAILIVIVGVLLTLTHDYWGGKLLGIFSVLISCSVVFIAFVISLENRKPAQTIAWLAVLGSFPFLGFLFYLLFGRNYWQQRRFKKKAESDEAVLLKFQEPSPIAIERLPMAPHQRPLLHLAYRIGQHPVSLASQTAVLTNGEETFAAIFDELEKAQHHIHLEYYIVRHDEIGQKLKHVLMEKACQGVHVRFLYDAVGSWKLSNAYIEELRAAGVEMIPFSPVRLPFLSNQINFRNHRKIIVIDGGVGFVGGLNIGDEYLGKDEYFGFWRDTHLLIRGEAVRTLQLIFLQDWYYMTGERLLTPEYLSPPLIVEEGQGGVQLIAGGPDQKWEVIKQLYFAMITSAKRSIWVASPYFVPDEDILTALKVAALSGIDVRLLAPKRPDKKIVFYASRSYFPELLEAGVKIYEYEKGFLHSKVIVVDGELASIGTANMDMRSFHLNFEVNAFLYYTDSTNKLVNDFLEDFRHASPIDYVQFQQRPFRVRIVESVSRLLSPLL

Gene
cls
Protein
Cardiolipin synthase
Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Length
494 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
56.518 kDa
Sequence
MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANSIWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDKEDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQYYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVIDGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIASSGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAGVKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYAKRSLWIKFKEGISQLLSPIL

Gene
cls
Protein
Cardiolipin synthase
Organism
Staphylococcus aureus (strain N315)
Length
494 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
56.518 kDa
Sequence
MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANSIWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDKEDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQYYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVIDGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIASSGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAGVKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYAKRSLWIKFKEGISQLLSPIL

Gene
cls
Protein
Cardiolipin synthase
Organism
Staphylococcus aureus (strain MSSA476)
Length
494 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
56.518 kDa
Sequence
MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANSIWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDKEDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQYYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVIDGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIASSGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAGVKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYAKRSLWIKFKEGISQLLSPIL

Gene
cls
Protein
Cardiolipin synthase
Organism
Staphylococcus aureus (strain MW2)
Length
494 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
56.518 kDa
Sequence
MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANSIWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDKEDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQYYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVIDGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIASSGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAGVKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYAKRSLWIKFKEGISQLLSPIL

Gene
cls
Protein
Cardiolipin synthase
Organism
Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Length
482 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
55.462 kDa
Sequence
MGLLAYLLVILLILNVFFAAVTVFLERRDTSATWAWLLVLTFVPIFGFIIYLIFGRKLSGKKIFDWKGQEKIGIQESTANQIEMIRQKEFPFSDPNVKKHRDLIYLLLVNDGAILTQDNEVELFIDGHEKFDALIADIEKAKDHIHLIYYIFHSDELGNRLMRVLERKAAEGLNVKIIYDAMGSRTTKKSFFRTFEKNGGLVRPFFPSKLPLINFRLNYRNHRKLAIIDGDVGYIGGFNIGDEYLGRSKKFGYWRDTHLRVHGKAVYAMQTRFIMDWNSASSTHKIDYKARYFPTFHGKGHTSMQIVSSGPDSEWQQIKNGYIKMINAAKKTIYLQSPYFIPDASLLEAIKIAALSGVDVRVMIPNKPDHAFVYRATTNYAGELMETGAKIFIYDNGFIHAKTLVVDGEIASVGTANMDFRSFRLNFEVNAFIYEKKMVQKLEDAFLEDILKSYQLTPELYAKRSLWIKFKEAVSRLLSPIL

Gene
cls
Protein
Cardiolipin synthase
Organism
Listeria monocytogenes serotype 4b (strain CLIP80459)
Length
482 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
55.362 kDa
Sequence
MGLLAYLLVILLILNVFFAAVTVFLERRDTSATWAWLLVLTFVPIFGFIIYLIFGRKLSGKKIFDWKGQEKIGIQESTANQIEMIRQKEFPFSDPNVKKHRDLIYLLLVNDGAILTQDNEVELFVDGHEKFDALIADIEKAKDHIHLIYYIFHSDELGNRLMRVLERKAAEGLNVKIIYDAMGSRTTKKSFFRTFQKNGGLVRPFFPSKLPLINFRLNYRNHRKLAIIDGDVGYIGGFNIGDEYLGASKKFGYWRDTHLRVHGKAVYAMQTRFIMDWNSASSTHKIDYKARYFPTFHGKGHTSMQIVSSGPDSEWQQIKNGYIKMINAAKKTIYLQSPYFIPDASLLEAIKIAALSGVDVRVMIPNKPDHAFVYRATTNYAGELMETGAKIFIYDNGFIHAKTLVVDGEIASVGTANMDFRSFRLNFEVNAFIYEKQMVQKLEDAFLEDILKSYQLTPELYAKRSLWIKFKEAVSRLLSPIL

Gene
cls
Protein
Cardiolipin synthase
Organism
Listeria monocytogenes serotype 4b (strain F2365)
Length
482 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
55.362 kDa
Sequence
MGLLAYLLVILLILNVFFAAVTVFLERRDTSATWAWLLVLTFVPIFGFIIYLIFGRKLSGKKIFDWKGQEKIGIQESTANQIEMIRQKEFPFSDPNVKKHRDLIYLLLVNDGAILTQDNEVELFVDGHEKFDALIADIEKAKDHIHLIYYIFHSDELGNRLMRVLERKAAEGLNVKIIYDAMGSRTTKKSFFRTFQKNGGLVRPFFPSKLPLINFRLNYRNHRKLAIIDGDVGYIGGFNIGDEYLGASKKFGYWRDTHLRVHGKAVYAMQTRFIMDWNSASSTHKIDYKARYFPTFHGKGHTSMQIVSSGPDSEWQQIKNGYIKMINAAKKTIYLQSPYFIPDASLLEAIKIAALSGVDVRVMIPNKPDHAFVYRATTNYAGELMETGAKIFIYDNGFIHAKTLVVDGEIASVGTANMDFRSFRLNFEVNAFIYEKQMVQKLEDAFLEDILKSYQLTPELYAKRSLWIKFKEAVSRLLSPIL

Gene
cls
Protein
Cardiolipin synthase
Organism
Listeria monocytogenes serotype 4a (strain HCC23)
Length
482 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
55.348 kDa
Sequence
MGLLAYLLVILLILNVFFAAVTVFLERRDTSATWAWLLVLTFVPIFGFIIYLIFGRKLSGKKIFDWKGQEKIGIQESTANQIEMIRQKEFPFSDPNVKKHRDLIYLLLVNDGAILTQDNEVELFVDGHEKFDALIADIENAKDHIHLIYYIFHSDELGNRLMRVLERKAAEGLNVKIIYDAMGSRTTKKSFFRTFQKNGGLVRPFFPSKLPLINFRLNYRNHRKLAIIDGDVGYIGGFNIGDEYLGASKKFGYWRDTHLRVHGKAVYAMQTRFIMDWNSASSTHKIDYKARYFPTFHGKGHTSMQIVSSGPDSEWQQIKNGYIKMINAAKKTIYLQSPYFIPDASLLEAIKIAALSGVDVRVMIPNKPDHAFVYRATTNYAGELMETGAKIFIYDNGFIHAKTLVVDGEIASVGTANMDFRSFRLNFEVNAFIYEKQMVQKLEDAFLEDILKSYQLTPELYAKRSLWIKFKEAVSRLLSPIL

Gene
cls
Protein
Cardiolipin synthase
Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Length
482 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
55.362 kDa
Sequence
MGLLAYLLVILLILNVFFAAVTVFLERRDTSATWAWLLVLTFVPIFGFIIYLIFGRKLSGKKIFDWKGQEKIGIQESTANQIEMIRQKEFPFSDPNVKKHRDLIYLLLVNDGAILTQDNEVELFVDGHEKFDALIADIEKAKDHIHLIYYIFHSDELGNRLMRVLERKAAEGLNVKIIYDAMGSRTTKKSFFRTFQKNGGLVRPFFPSKLPLINFRLNYRNHRKLAIIDGDVGYIGGFNIGDEYLGASKKFGYWRDTHLRVHGKAVYAMQTRFIMDWNSASSTHKIDYKARYFPTFHGKGHTSMQIVSSGPDSEWQQIKNGYIKMINAAKKTIYLQSPYFIPDASLLEAIKIAALSGVDVRVMIPNKPDHAFVYRATTNYAGELMETGAKIFIYDNGFIHAKTLVVDGEIASVGTANMDFRSFRLNFEVNAFIYEKQMVQKLEDAFLEDILKSYQLTPELYAKRSLWIKFKEAVSRLLSPIL

Gene
cls
Protein
Cardiolipin synthase
Organism
Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)
Length
482 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
55.442 kDa
Sequence
MGLLAYLLVVLLILNVFFAAVTVFLERRDTSATWAWLLVLTFVPIFGFIIYLIFGRKLSGKKIFDWKGQEKIGIQESTANQIEMIRQKEFPFSDSNVKKHRDLIYLLLVNDGAILTQDNEVELFIDGHEKFDALIADIEKAKDHIHLIYYIFHSDELGNRLMRVLERKAAEGLNVKIIYDAMGSRTTKKSFFRTFEKNGGLVRPFFPSKLPLINFRLNYRNHRKLAIIDGDISYIGGFNIGDEYLGLSKKFGYWRDTHLRVHGKAVYAMQTRFIMDWNSASSTNKIDYKPRYFPTFHGKGHTSMQIVSSGPDSEWQQIKNGYIKMINAAKKTIYLQSPYFIPDASLLEAIKIAALSGVDVRVMIPNKPDHAFVYRATTNYAGELMETGAKIFIYDNGFIHAKTLVVDGEIASVGTANMDFRSFRLNFEVNAFIYEKKMVQKLEDAFLEDILKSYQLTPELYAKRSLWIKFKEAVSRLLSPIL

Gene
cls
Protein
Cardiolipin synthase
Organism
Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Length
479 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
55.123 kDa
Sequence
MGITSLLLGLTFVLNIALAISIIFLERKDPTSSWAWVMVLLFIPILGFFLYLIFGKPISNRKIFSWDKKSRLGVKTTVQSQLRLLEENQFEFNQPDLIEHKDLVYLHLKNDEAIYTQNNGVDIFTDGQTKFDALLEDIEKAKKHIHIQYYIMRSDGLGNRLADMLIKKVNEGVEVRVLYDDMGSRSLKNSYIKRLKRAGVMVEAFFPSRFIVNFKINYRNHRKLAIIDGYIGYLGGFNVGDEYLGINKKFGYWRDTHLRVIGDAVQSMQTRFILDWNQASRDTILYNEDYYQTVSAGNVGMQIVTSGPDSEYEQIKNGYIKMIMEANDYICIQTPYFIPDESLRDALKIAVLSGVHVKIMIPNKPDHPFVYWATLSYCGDLIQAGAEIFIYQNGFLHAKTIIVDGRIASVGTANIDVRSFRLNFEVNGFLYDSEVVNRLQNEFDADLEKSTQMTRKLYDQRSIGIRFKESISRLISPVL

Gene
cls
Protein
Cardiolipin synthase
Organism
Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)
Length
476 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
55.052 kDa
Sequence
MHLFINMIFLINIVFIISIIFIERRNPQTTWAWILILTFLPILGFIIYILFGQNITREKNFKRKILDDKTKQKYLNSFKSHYKLDNISLKYKDLIMMNFNNDNSTYTQRNDIDLYFDANSLFEEMIDEINKAEKFIHMEFYIFKSDEIGKKILQALTKKAKEGVEVKLLVDSIGNSIHKKDIDKLKAAGGDFKIFFPGFCKYINLRINYRNHRKILIIDSKVAFLGGFNIGDEYLGKDKNIGHWRDTHTKIKGLAINDLEGRFLLDWSYANESDLDIDLKKYFINPHSTDLPKKIIGAQIVSSGPDHTEQQIKNGYFKIINSAKKNLFIQTPYFVPDEPMLEALRLAALSGVDVKIMLPGNPDHKFMGWIANSYFESLLNAGAKIYLYEKGFLHAKTIVADSSICSVGTANMDIRSFSLNFESNIFIYNEAISKSMEEQFFKDLKVCTKVTLESFEKRSIISRIGESIIRLVSPLM

Gene
cls
Protein
Cardiolipin synthase
Organism
Clostridium perfringens (strain 13 / Type A)
Length
476 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
55.04 kDa
Sequence
MHLFINMIFLINIVFIISIIFIERRNPQTTWAWILILTFLPILGFIIYILFGQNITREKNFKRKILDDKTKQKYLNSFKSHYKLDNISLKYKDLIMMNFNNDNSTYTQRNDIDLYFDANSLFEEMIDEINKAEKFIHMEFYIFKSDEIGKKILQALTKKAKEGVEVKLLVDSIGNSIHKKDIDKLKAAGGDFKIFFPGFCKYINLRINYRNHRKILIIDSKVAFLGGFNIGDEYLGKDKNIGHWRDTHTKIKGLAINDLEGRFLLDWSYANESDLDIDLKKYFINPHSTDLPKKIIGAQIVSSGPDHTEQQIKNGYFKIINSAKKNLFIQTPYFVPDEPMLEALRLAALSGVDVKIMLPGNPDHKFMGWIANSYFESLLNAGAKIYLYEKGFLHAKTIVADSSICSVGTANMDIRSFSLNFESNIFIYNEAISKSMEEQFFKDLKVCTKVTLESFEKRSIISRIGESITRLVSPLM

Gene
cls
Protein
Cardiolipin synthase
Organism
Clostridium perfringens (strain SM101 / Type A)
Length
476 amino acids
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Mass
55.123 kDa
Sequence
MHLLINIIFLINIIFIISIIFIERRNPQTTWAWILILTFLPILGFIIYILFGQNITREKNFKRKILDDKTKQKYLNSFKSHYKLDNISLKYKDLIMMNFNNDNSTYTQRNDIDLYFDANSLFQEMIYEINKAEKFIHMEFYIFKSDEIGKKILQALTKKAKEGVEVKLLVDSIGNSIHKKDIDKLKAAGGDFKIFFPGFCKYINLRINYRNHRKILIIDSKVAFLGGFNIGDEYLGKDKNIGNWRDTHTKIKGLAINDLEARFLLDWSYANESDLDIDLKKYFINPHSTNLPNNIIGAQIVSSGPDHTEQQIKNGYFKIINSAKKNLFIQTPYFVPDEPMLEALRLAALSGVDVKIMLPGNPDHKFMEWIANSYFESLLNAGVKIYLYEKGFLHAKTIVADSSICSVGTANMDIRSFSLNFESNIFIYNEAISKSMEEQFFKDLKVCTKVTLESFEKRSIISRIGESIIRLVSPLM

Gene
CLS
Protein
Probable cardiolipin synthase (CMP-forming)
Organism
Drosophila melanogaster
Length
322 amino acids
Function
Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
Similarity
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
Mass
36.456 kDa
Sequence
MLPAIIFRQVQRPLHHGAATLEHVLGVGGSSFVNCLNRYAAATGFIRISFLDIKRRRNYELARLRLYADEKKQSLHLRTLQGRHLLQGVIERKNFLVDDIREARHKVQERVREKIDEIREERENIMTIPNMLTISRAVLSPYIGYVIVQGDFTLGMSLLAFAGITDLLDGQIARRWPSQASKFGSFLDPMADKLLMGSLVISLCYTDLLPMWLMGIVVFRDVFLLGAGFVIRYISLPPPKTFSRYFDATHVTAQLEPTLLSKINTGVQLATIGLSLGAPIWNYLDHPALQGLWYLTGLTTAATALSYVMNRHNTFKIIQKKT