CLN3

G1/S-specific cyclin CLN3

580 amino acids

Essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start.

Belongs to the cyclin family.

64.991 kDa

MAILKDTIIRYANARYATASGTSTATAASVSAASCPNLPLLLQKRRAIASAKSKNPNLVKRELQAHHSAISEYNNDQLDHYFRLSHTERPLYNLTNFNSQPQVNPKMRFLIFDFIMYCHTRLNLSTSTLFLTFTILDKYSSRFIIKSYNYQLLSLTALWISSKFWDSKNRMATLKVLQNLCCNQYSIKQFTTMEMHLFKSLDWSICQSATFDSYIDIFLFQSTSPLSPGVVLSAPLEAFIQQKLALLNNAAGTAINKSSSSQGPSLNINEIKLGAIMLCELASFNLELSFKYDRSLIALGAINLIKLSLNYYNSNLWENINLALEENCQDLDIKLSEISNTLLDIAMDQNSFPSSFKSKYLNSNKTSLAKSLLDALQNYCIQLKLEEFYRSQELETMYNTIFAQSFDSDSLTCVYSNATTPKSATVSSAATDYFSDHTHLRRLTKDSISPPFAFTPTSSSSSPSPFNSPYKTSSSMTTPDSASHHSHSGSFSSTQNSFKRSLSIPQNSSIFWPSPLTPTTPSLMSNRKLLQNLSVRSKRLFPVRPMATAHPCSAPTQLKKRSTSSVDCDFNDSSNLKKTR

CLN3

G1/S-specific cyclin CLN3

465 amino acids

G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start. Required for budding and for cell cycle progression and morphogenesis in environment-induced hyphae. Degradation is mediated by GRR1. Through binding to CDC28, controls the phosphorylation of SLA1 which regulates cortical actin patch dynamics.

Belongs to the cyclin family.

53.177 kDa

MFPNSPDAFHQVRMMQSSIKASNFKLQSMEFRCHSNNVCEYQMEMLHHLLSVEAKTLPNLSLIEQQPEIKLGMRPLLLDFLMEVITILSLSRSTFPLTVNLIDRYCSTRIVKKQHYQLLGLTSLWISCKNLDSKFKVPTLNDLRKICVDSYYKELFVEMEKHILKSLEWVVNAPTFDAFIDLYSNLLISNSSNFEVANIIKKSSHKIKLFSNYIGELFQFYPNIYYDYTSSQIALIAILITVLTLKIPVDLISLLNFYNGLVKTEMFKSNVEQGAEDQFEEILSVDSFKSLFNKSFFKNLIKIIDNPPSSLKIKYFAENGKYSVLMKQLVTTASNTLKCILDPVPTTPKANSFVKHQQQQHHYHPRPPMSINTSMIPLTPVSNSTSPNRFSPDQIFSENESTPGIAFGTMTPDSQSTSPGEKRSYECIDELEIGTSTIAGYTLKNHDTLKRSKSANYGTLFYLQQ

cln3

Protein btn-1

464 amino acids

Involved in vacuolar transport and vacuole pH homeostasis. Also required for cytokinesis (By similarity).

Belongs to the battenin family.

50.496 kDa

MNRSPSSSGLLPLPGAPSSSWALYRARLSSLLQSVDTAVFIAFWLFGLINNVLYVIILSAAQDLVGNGIPKGVVLLADVMPSFLTKLVAPYFIHRIPYATRIFIFVTLSSAGMLLIAFTPPSRSVAVKLIGVVLSSISSGGGELSFLGLTHYYGHMSLAAWGSGTGGAGLIGSLLYVMLTDWIGLSVKTSLLASAFLPIIMLVSFFLILPHGPLRASARKTYEPIANRDSFQEESEGAENNFDDIPTSTASSSLLAPGPAVAATAYSSHPTEDARKDSLAAKIQRSKSLFFPYMLPLLLVYIAEYTINQGVSPTLLFPLESSPFAEFRSFYPFYGFLYQVGVFISRSSIAFIRIHHLYLPSLLQVANLVLLTLHALLNFIPSVYIVFVIIFWEGLLGGCVYVNTFAEIMEHVPAEDREFSLGATSVSDSGGICVASFLSMAMEIWLCNWQVDHGRDWCRRIKAG

CLN3

Battenin

438 amino acids

Involved in microtubule-dependent, anterograde transport of late endosomes and lysosomes.

Belongs to the battenin family.

47.933 kDa

MGGCAGSRRRLLDSEEEETAPEPRPPRSYHKGALWKNVMGFWLLGLCNNFSYVVMLSAAHDILSHQRASGNQSHVDPDPPPTAHNSSSRFDCNSVSTAAVLLADILPTLIIKLLAPLGLHLLPYSPRVLVSGICAAGSFILVAFSHSVGTSLCGVVLASISSGVGEVTFLSLTAFYPRAVISWWSSGTGGAGLMGALSYLGLTQAGLSPQHTLLSMLGIPALMLASYFFLLTSPEPQDPGGEEEAETSARQPLIDSETPESKPDSSSNLSLQERWTVFKGLLWYIVPLVLVYFAEYFINQGLFELLFFRNTSLNHAQQYRWYQMLYQAGVFVSRSSLHCCRIRFTWVLALLQCLNLAFLLVDVWFSFLPSIYLVFLIILYEGLLGGAAYVNTFHNIALETSDQHREFAMAAACISDTLGISLSGLLALPLHDFLCHLS

CLN3

Battenin

438 amino acids

Involved in microtubule-dependent, anterograde transport of late endosomes and lysosomes.

Belongs to the battenin family.

47.623 kDa

MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRFDCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEAPESKPGSSSSLSLRERWTVFKGLLWYIVPLVVVYFAEYFINQGLFELLFFWNTSLSHAQQYRWYQMLYQAGVFASRSSLRCCRIRFTWALALLQCLNLVFLLADVWFGFLPSIYLVFLIILYEGLLGGAAYVNTFHNIALETSDEHREFAMAATCISDTLGISLSGLLALPLHDFLCQLS

CLN3

Battenin

438 amino acids

Involved in microtubule-dependent, anterograde transport of late endosomes and lysosomes.

Belongs to the battenin family.

47.545 kDa

MGGCAGSRRRLSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHERTSGNQSHVDPGPAPIPHNSSSRFDCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVLASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESSARQPLIRTEAPESKPGSSSSLSLRERWTVFKGLLWYIVPLVVVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLRCCHIRFTWALALLQCLNLAFLLADVWFGFLLSIYFVFLIILYEGLLGGAAYVNTFHNIALETSDEHREFAMATTCISDTLGISLSGLLALPLHDFLCQLS

Cln3

Battenin

438 amino acids

Involved in microtubule-dependent, anterograde transport of late endosomes and lysosomes.

Belongs to the battenin family.

47.657 kDa

MGSSAGSWRRLEDSEREETDSEPQAPRLDSRSVLWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASGNQSHVEPGPTPTPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGVCSAGSFVLVAFSQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGSLSYLGLTQAGLSPQHTLLSMLGIPVLLLASYFLLLTSPEPLDPGGENEAETAARQPLIGTETPESKPGASWDLSLQERWTVFKGLLWYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLQCCRIRFTWVLALLQCLNLALLLADVCLNFLPSIYLIFIIILYEGLLGGAAYVNTFHNIALETSDKHREFAMEAACISDTLGISLSGVLALPLHDFLCHLP

cln3

Battenin

421 amino acids

Belongs to the battenin family.

46.557 kDa

MGKDYTFIRNWISFHFMGNINNFSYCVVNAASGNLSAYFHNSKNIGIILWANIAFGLVSRLVNTFLIENVNSKLKIVVNCLFMSIGLIGVALSVYVNFGFCIAAIAFVGIASSFGESVILSYMKKFPAELVNGWSSGTGIAGVCGSLFYIAMVAAGLSNSTIFYMMLPTVAVYFLLFFFGLKVPNHLEEDRTDNHNNSNNSSNNSKYTEKQSLVKKDQLIEDIDDGGGAEVAPPGETKKQRYIRCARLVWFNAVNLALVYFFEYVASVGGADLALKKDPNNDNFFIANAFAIFSFCYQLGVLISRSSLQFVKIKHIGVITILQGINMVFWIIQAKYKMVTSVWVLFILMVYCGLLGGASYVNVFYLILHQKNIPNEDRELCINYAALLVTVGITLAACFILVMDHTFLASEVPKTDSSSST