About Products Protein Database Contact

CINP

Gene
CINP
Protein
Cyclin-dependent kinase 2-interacting protein
Organism
Bos taurus
Length
212 amino acids
Function
Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling (By similarity).
Similarity
Belongs to the CINP family.
Mass
24.128 kDa
Sequence
MEAKTLGTVTPRKPVLSVSARKIKDNAADWHNLILKWETLNDGGFATANSIANMKISLSSKDKIELASSGLASNDCAEKEHPEYSRELETLCEELQATLEGLTKIQMKMEKLSSTTKGVCELEDYHHGEERKRPPLFHTWPTAHFYEVSRKLSDMYSQELRLKRTVVEQLAHTADRDLALSYLSMWLHQPYLEAGSWLLLESMLLETGHRVL

Gene
CINP
Protein
Cyclin-dependent kinase 2-interacting protein
Organism
Homo sapiens
Length
212 amino acids
Function
Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling.
Similarity
Belongs to the CINP family.
Mass
24.324 kDa
Sequence
MEAKTLGTVTPRKPVLSVSARKIKDNAADWHNLILKWETLNDAGFTTANNIANLKISLLNKDKIELDSSSPASKENEEKVCLEYNEELEKLCEELQATLDGLTKIQVKMEKLSSTTKGICELENYHYGEESKRPPLFHTWPTTHFYEVSHKLLEMYRKELLLKRTVAKELAHTGDPDLTLSYLSMWLHQPYVESDSRLHLESMLLETGHRAL

Gene
Cinp
Protein
Cyclin-dependent kinase 2-interacting protein
Organism
Mus musculus
Length
212 amino acids
Function
Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling (By similarity).
Similarity
Belongs to the CINP family.
Mass
24.104 kDa
Sequence
MEAKTLGIATPRKPVLSVSARKLKDNAADWHNLILKWDSLSDKGFTTASSIANLKVSLLSKEKVELESSSPASMEEEEKTNLDYDKGLEALCEELQAILDGLTKIQMKMEKLSSTTKGICELENYHYREESSRPPLFHTWPTAFFYEVSRRLSEAYKKELLLKHTIGAELAHTADRNLSLTYLSMWLHQPYIESNSKLQLESMLLETGHRAL

Gene
cinp
Protein
Cyclin-dependent kinase 2-interacting protein
Organism
Xenopus laevis
Length
207 amino acids
Function
Interacts with the components of the replication complex. Regulates checkpoint signaling (By similarity).
Similarity
Belongs to the CINP family.
Mass
23.974 kDa
Sequence
MESKSPGYITPKKPALSASARKIKDNAADWHNLMLKWETYNNDSFNIASKIVNLKITAESADRMLLDEPSPNKDNITTDKVELDRLCSELLQTIENMEKIWTKMEKITATFKGICDLEAYQFPGDTSKPTHFHTWPTTLFYETSMKMVDMYKKEIQLKRTIVGDLAHTSDQDLRMVYLSCWLYQPYIDNNIKVLLESMLLETGHRPI