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CIMG_02370

Gene
CIMG_02370
Protein
Eukaryotic translation initiation factor 3 subunit D
Organism
Coccidioides immitis (strain RS)
Length
598 amino acids
Function
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
Similarity
Belongs to the eIF-3 subunit D family.
Mass
66.474 kDa
Sequence
MAPLSLTDIVSALPSEEDAWGPPVPTGNHLDGVPYAPFSKGDKLGRMADWGADSKDSRERGRQAYNRNYRDQQVYGAGTSSLFAVQVAEDESSFSVVDNTRTSVKTRGFGRGGGTIFRGRGQRGGAQRGRGGAFQRPAGGRGGQAGGDRYYDQRGGRGNRGRRFGWKDYDKPQRNRDSSVAIRPEWSMLEEIDFSRLSKLNLETPDGEDLDNYGFLYYYDRSYDKAPVKNTERRLRALERAAYNVTTSADPVIQELAEKDEATVFATADILSMLMCASRSVYSWDIVIVKHGNKIYFDKRDNASIDLVTVNENAADAPMEASEGQAKHDSINTPGALALEATIINHNFALQTVVESDSAKVEFSHPNPFYNPSEETEPLASKGFKYRRFDLSLEKDEEPVQIIVRTEIDAVLKNNISGEDQHVTLKALNEFDHKAQGAGGALDWRSKLYSQRGAVVATEMKNNNVKLARWTTQAILAKSDVMKLGFVTRANPRSATAHMILGVIGYKPREFALQMNLNMANGWGIVRTIIDLVNSLDARDEEEGDDAQEDKIKKYILVKDPNKSVVRLYSVPANTFEEEDDTGAKAEKDEESEEKDEE