Chl1

Neural cell adhesion molecule L1-like protein

1209 amino acids

Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane.

Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

135.074 kDa

MMELPLCGRGLILSLIFLLLKLSAAEIPLSVQQVPTIVKQSYVQVAFPFDEYFQIECEAKGNPEPIFSWTKDDKPFDLSDPRIIAANNSGTFKIPNEGHISHFQGKYRCFASNRLGTAVSEEIEFIVPGVPKFPKEKIEPIDVEEGDSIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMSQRGDLYFANVEENDSRNDYCCFAAFPKLRTIVQKMPMKLTVNSSNSIKQRKPKLLLPPAQMGSLSAKTVLKGDTLLLECFAEGLPTPHIQWSKPGSELPEGRATIEVHEKTLKIENISYQDRGNYRCTANNLLGKASHDFHVTVEEPPRWKKKPQSAVYSTGSSGILLCEAEGEPQPTIKWRLNGLPIEKHPFPGDFMFPREISFTNLLPNHTGVYQCEASNIHGTILANANIDVIDVIPLIKTKNEENYATVVGYSAFLHCEYFASPKATVVWEVADETHPLEGDRYHTHENGTLEIYRTTEEDAGSYSCWVDNAMGKAVITANLDIRNATKLRVSPKNPRIPKSHVLELYCESQCDSHLKHSLKLSWSKDGEAFEMNGTEDGRIVIDGAYLTISNITAEDQGVYSCSAQTSLDSTSEKTQVTVLGVPDPPGNLHLSERQNRSVRLSWEAGDDHNSKISEYIVEFEGNREEPGKWEELTRVQGEETDVVLSLAPYVRYQFRVTAVNEVGRSHASLPSDHHETPPAAPDKNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYKVSWKPQGAPEEWEEEIVTNHTLRVMTPTVYAPYDVKVQAINQLGSSPDPQPVTLYSGEDYPSTAPVIQRVDVMNSTLVKVTWSSIPKETVHGLLRGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDPFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPSFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYELGELNEINVTTPSKSSWHLSNLNSTTKYKFYLRACTSRGCGKPISEEGATLGEGSKGIRKITEGVNVTQKIHPVEVLVPGAEHIVHLMTKNWGDNDSIFQDVIETRGREYAGLYDDISTQGWFIGLMCAIALLTLILLTICFVKRNRGGKYSVKEKEDLHPDPEVQSAKDETFGEYSDSDEKPLKGSLRSLNRNMQPTESADSLVEYGEGDQSIFNEDGSFIGAYTGAKEKGSVESNGSSTATFPLRA

CHL1

Neural cell adhesion molecule L1-like protein

1208 amino acids

Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane (By similarity).

Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

135.071 kDa

MEPLLLGRGLIVYLMFLLLKFSKAIEIPSSVQQVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFRIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSSNSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRETKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLSWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDVPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTRVQGKKTTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHTLRVMTPAVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGKPITEESSTLGEGSKGIGKISGVNLTQKTHPIEVFEPGAEHIVRLMTKNWGDNDSIFQDVIETRGREYAGLYDDISTQGWFIGLMCAIALLTLLLLTVCFVKRNRGGKYSVKEKEDLHPDPEIQSVKDETFGEYSDSDEKPLKGSLRSLNRDMQPTESADSLVEYGEGDHGLFSEDGSFIGAYAGSKEKGSVESNGSSTATFPLRA

chl1

ATP-dependent DNA helicase chl1

1068 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

118.554 kDa

MASTLPIPDINVIAPSFIQRDSQNSDNMKPPPTDFNHPYTPYPIQTAFMQTLYSVLDRTVAVSPPTTTNSTNNTAPSATFSSTAATLIPSNPSTSPSTPPLINPTTAPTVHLADRATEPSLSVTPRTTTSKDKDKGPSSSSSVPKGHAQIALFESPTGTGKSLSLICGSLTWLRNHKRLQFDSEIEKIQQQMEASGEPEWMVESAIKRKREELAQKYEEMERTLERIRQKEREMEKEGEEGQARGGKRRKLDRGKGDEEKGGKKKESGGSRGLTASDEDKEFLIGDWRDEGGLDENDPMGQLSKETRELLEKVGMGTAGGKKEANEGPVAEEEIKIFYTSRTHSQLTQFIQELRRPEFPASVPTPNPQEKPAKEIVKQIPLSSRQKLCINPTVNKLGTLAAINERCQSLQQPKTPKDQRCPYLPNAANLKATHEFRDTALATLPDIEDLYQTGKQLQICPYYASRAAIPGAEVITLPYPLLLQKSAREALGIRLEGNIVIIDEAHNIMDAVSNVHAAEIKYTDLKRAKLSLGMYYQRFHQKLTGENKVMVAQLQRVVEALGVYLKTKLDKAALGLKADQEGIVLDTSLLLKTGGADQINLYKLIRYVQESKLAFKIEGYISYCEEEGRDTDDEEAETEIKARQGRPPVLHTLCSFLTALTNLSSEGRIFYEKIPPPRGELQDMKLSYMLLSPTHAFSSIAESARAVILAGGTMSPFEDYKAHLFPDVPPEKITTLSCGHVIPPDNLCVWTLGSIAPNPKVDTGIGEDCFDFTFAKRSNPNMINRLGLVLLNLCSVVPDGVVAFFPSYGYLEEVIGVWKTHEQAMGPKTIWERLESKKALFIDSKTESSEQTLQKYSDVIHSEVRPLSPAGSRVKGAMLLSVIGGKMSEGINFSDRLGRCVVVVGMPYPNPHSPEWLARREYLEANFIKRYTASQQTSTATAPLPAPVIPPPSNTTHYSTNPSSSRNKDKHKPANVRKLAARDSHQFYENATLRAVNQSIGRAIRHQNDYAAIVLIDNRFEKEHVRAKLPGWIREGWDETQRQAKEDGKALKGLQGMMGRVNMFFRGKN

CHL1

ATP-dependent DNA helicase CHL1

902 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

100.489 kDa

MDLTDDSPDGEVKIHKKDFHHPYTPYPIQEKFMQTVYDVLEQGKIGILESPTGTGKSLSLICGSLTWLRDFKRKEFEGILNDGFENSEEPEWMIEAAKVRKKRELIGRREEMERKLGRIRERERCERDRMSGNGNGNMRGGKRRKVGGDGEGDLVGGSNGSNEDEFLLEDWESDGEIGGSGKKKTGDEAIFSKETLELKKSIGMWKFPSPMPLEEFPSKTTEKDKDNLHEHLRHLPLGSRKNLCINPKVNKLNSVTAINERCAELQQSSTPKEHKCPHLPNKDNKPLVSTFRDHALATIRDIEDMGALGKEISICPYYASRSAIKPAEIVTLPYPLLLQKSAREALGISLKGHVVIIDEAHNLMDAIAGIYGTEMSLKELKLAKEMLGNYFMKFAKRLKGKNRIYVAQAIRVVDSLMGYLMKRLEGTEIDGVVDQKELLAGKGADQIDLFKLIRYLQESKLARKVESYTEHTRNIKQASTIPHNNKETPKSTTPILHTLTSLLLALTHPTTEGQLFFLKSTSTSPSPSPDLITLKFQLLNPAPHFESIVSSARAIILAGGTMSPFSDYTSILFPSIPSHKITTLSCGHVIPKTHLFASTVSRGPTGIPFKWTFANRGNTDMMDELGRVLLNVCTIVPDGVVVFFPSYNFLSTILYRFSIPSSGTGSATATATGTEKGKGKTILERLSEKKPIFQESKEESVETILAAYAKSIAEGKGALLFSVVGGKLSEGINFSDALGRCVMIVGLPFPNMHTAEWKRRLRFIEESAVERLTSFYQEKESNNKDGNGNEEEGNGKKKENREKIQRDQILQQAKGEARDYFENVCMRAVNQCVGRAIRHRGDWAGILLLDERYKGERVVGKLAGWIREGVLRGEGMGMGDAGGFGRLMGGLGRFCRGRREVL

CHL1

ATP-dependent DNA helicase CHL1

892 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

101.159 kDa

MTSLPSPSARTCRDYHHPYDPYDIQLQFMDALYETLQNGYKIGMFESPTGTGKTLSIICSSMTWLRDYKRNYNLNTKLLEGNVSNNDDKQAGEDHEGTKGKDDDDDDDDDDDDDDDDDDDDDEPEWVKMAYQKSIVDKSKNKLKDFERHLNEVDQAYKRRVQKNKEANLGTKIRNVARKQQTQEDPEESFLPNDYNETNQESFINDVESRNLQLSTEIERLMKSSIINNNGSGSNAVDDAAAAAAAAATDDECPTKIFFTSRTHSQLNQFSSQLRLTKFDASFKDLEERTKYLPLGSRKQLCINDKVKNRKGEQSINDACIDLQKTKKGCTYLPNPSNSSTISSATKEFADLSLAQIRDIEDLGDLGSSLHTCPYYSVREGIKLAEVISLPYQLLLQSGSRDALKLDIKNSIIIIDEAHNIFDTLTSLYSVKITAAQLSRTIKALKIYMTKFLKKLNSGNRINLMKLTKLCKLLMDFLQSDLAKSAKLGDQVVGEEIFQGSTGDLVNIHKMEAYLNKSKIAFKLQSYMEKIGVEDVGTDFKLNSSSPILFDIVKFLKCLSYPKKEGKFFWDRIYGDNGGCEVSLNYMLLDPCAVFKEIVDQAKCVILCGGTMEPTSDFTDYLFPSIKHNKIKKFACGHIIPKNNLKVIPVGQYYGNFDFLYNRRNDLDQFKRLGEFLIKICEIVPAGIVVFISSYQLLSDIVKIWRETTIYSRLNLLKQVFEESVENTKLTSLLSEYSYVINTQCKGAILLAVVGGKMSEGINFSDNLARAVIMVGMPYPNAFSGEIVAKRNFIEEQVITKGGTIQQARAKSYEYYDNLCMKAVNQSIGRSIRHAKDYAIIILLDYRYQTPKVQGKLSKWVRDRIANNTTANTFDPFLETKKFFSFPIRSTK

chl1

ATP-dependent DNA helicase chl1

874 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

98.373 kDa

MELQRNDFHHPYSPYDIQLQLMRALYSCLEQGKVAVFESPTGTGKSLSLICGSLTWLRDHKRSAFQTAVDNATCDDDEPEWMLDFARRESSRMMTEKRKELEERLEKTRKEEEQQRIALENPEGPRKKQKYSIPLTESGGLSEDQFALDDYDSENEEHSKPRDELAHTSELSPSTLELLERFKGQISTAKPGSDDADNDEVKIFYCSRTHSQLTQFAGELRRVKMPWSIPKDLLSTDLTGEEELEERVKHVTLGSRKNLCINPRVSSLENATAINERCLDLQQPNVNPQHRCPFLPSKEDERQVLQFRDHALSTVKDIEDLGKLGKKIGICPYYASRSVVKDSEVCCLRARSSIDLVPDEWQIVTLPYPLLLQRSAREALNSSVKGHVIIIDEAHNLMDAISNIHSVTVTLSQLQTSLSQLTIYGRKFKTRLKGKNRSYVAQVIRLLSSIAAHLRSLLESGKAPEGPVLISELMSGKGVDQINPYKLSRYLQESKLARKVDGYVEFTRDPSDKQASRSPTVPVLFHIQGFLLSLMNPSAEGRLFYSKEQGDIQLKYMLLDPTNQFRELVEDARAIILAGGTMSPMTDYMNHLFSYVPASRLDTFSYGHVIPPENLIAHTLVRGVQGSEFDFTYDARDSEKMIMDLGRTIATLCHVIPDGVVAFFPSYDYLGRVLNIWKKPMLGEQGQTVYNLIGQKKPILSESRDMTVTTEELLHTYANTVDSGRGALLLSVVGGKLSEGINFSDKLGRGVLIVGLPFPNIRSAVWQAKIQYIEQKTHQQATGSEASRQLAAKAAGRDFYENSCMRAVNQCIGRAIRHRNDYAAIVLVDRRYEKPGIQAKLPAWIKQSMVGSSVQRPAGATVQSLAKFFASKST

CHL1

ATP-dependent DNA helicase CHL1

861 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

97.469 kDa

MNPSSKTFYHPYSPYDIQVQFMRSLYTCIEECKVGIFESPTGTGKSLSLICGSLTWLRDHKRSVFLEDIENSDGDDEPEWILQYSRKEKRRIIRERRKRVEDRLSRIRKEELLREKAAIANIPFKKQRLEDGKRHLDKMADDGAFELDEYDSDNQETSTHDAKSNSDLSATTIALLEKLSGSAEIQDDFEEENAVKIFYCSRTHSQLAQFARELRRVVFPPSIPPETEDGEIDTQGEGRRHPDTELEEPTKHVSLGSRKTMCINPKVRRLGNATAINERCLDLQSSNVLPGHKCPFAPSKENELAINDFRDHVLAEVHDIEDIGKIGQRTGICPYYASRSVIGHSEIVTLPYQLLLQKSARDALDISLKDHVIIIDEAHNLMDVIANIHSVNVSLTQLRIGLEQLTIYARKYKARLKGKNRVYVAQVMRLLGSIAKYLESVLAARELREGAVDPSYLMSGKGIDQINLHKLSRYLQESKLARKVDGYIESSTSLEEKNPETSTTVPVLFQVQSFLLSLMNPSAEGRLFFEKNGNDVLLKYTLLDPTAHFREAVEEARAVILAGGTMSPMSDYRDHLFSYLAPGQLRTFSYGHVIPTSNLSARPVSRGILDTEFDFTFEKRNSRAMIIDLGKTISEICKATPDGVVAFFPSYDFLNQVVEIWKQPCSNSGNPSILDSLGLVKPLLYESKEKAMNTEALLQKYANFIDEGKGALLLSVMGGKLSEGINFSDRLGRGVIVIGLPFANIRSAEWQAKIQYVERKTYERSSGGEETRRSKAKLAGRDFYENACMRVVNQCIGRAIRHQHDYAAILMFDRRYGTARIQSKLPEWIRRSLISAPIGATISNLYTFFEEKSSIEVTKEK

chl1

ATP-dependent DNA helicase chl1

861 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

96.66 kDa

MGSQPQNFNHPYSPYDIQLQFMRALYTCLEEGKVAVFESPTGTGKSLSLICGSMTWLREHKRKALQDTVNKASCSAGDDDGEPEWMLEFAKRESARAVTEKRRALEARLEKIKVEEEKQRHAHATDHPGEARKRQRLDTSSGDPGQEQDDQFILDDYDSDAEERITYSKKLGDISGLSTSTLELLERFKEQFSASAEDETGHEDDDVKIFYCSRTHSQLSQFSSELRRVKMPSSMPAELSTSDANTDDAEERVKHLTLGSRKNLCINPKVMSLGNATAINERCLELQQPGVAAEKRCPYLPSKEDEGQVLQFRDHTLATIKDIEDMGKLGKRMGICPYYASRSVLKHSEIVTLPYPLLLQRSARDALDLSIKNHVVIIDEAHNLMDAICNIHSVTITLSQLQTALSQLTTYARKHKARLKGKNRSYIAQIIRLISSIADHLRSTIGENLPAEGAVDPSDLMAGKGVDQINPYKLSRYLQESKLARKVDGYVEFSKDKNQQSDDKPSSPVLFLVQSFLLPLMNPSAEGRFFYLKFHDDIQLKYMLLDPTNHFREIVEDARAVILAGGTMSPMSDYRNHLFSYIAPSRLDTFSYGHVIPPENLIAHTLVNGVLGSEFDFTYDSRDSEKMILDLGRTVAMLCQAIPDGVVAFFPSYDYLSRILAIWRKPLVGEKGQTILSLIERKKSILYEGRDMGAKTEDLLQEYTRTIDSGQGALLLSVVGGKLSEGINFSDKLGRGVLIIGLPFPNIRSAVWQAKIQYVEQKTYNSSSGSEKDRLSIAKAAGKDFYENACMRAVNQCIGRAIRHRNDYAAIVMIDRRYEKANIQGKLPAWIKQSMLRRSVRRPASALAADLSNFFSGRSSG

CHL1

ATP-dependent DNA helicase CHL1

861 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

98.822 kDa

MDKKEYSETFYHPYKPYDIQVQLMETVYRVLSEGKKIAILESPTGTGKTLSLICATMTWLRMNKADIFTRMETNIKTNEDDSENLSDDEPDWVIDTYRKSVLQEKVDLLNDYEKHLNEINTTSCKQLKTMCDLDKEHGRYKSVDPLRKKRKGARHLDVSLEEQDFIPRPYESDSENNDTSKSTRGGRISDKDYKLSELNSQIITLLDKIDGKVSRDPNNGDRFDVTNQNPVKIYYASRTYSQLGQFTSQLRLPSFPSSFRDKVPNEKVKYLPLASKKQLCINPKVMKWKTLEAINDACADLRHSKEGCMFYQNTNEWRHCPDTLALRDMIFSEIQDIEDLVPLGKSLGICPYYASREALPIAEVVTLPYQYLLSESTRSSLQINLENSIVIIDEAHNLIETINSIYSSQISLEDLKNCHKGIVTYFNKFKSRLNPGNRVNLLKLNSLLMTLIQFIVKNFKKIGQEIDPNDMFTGSNIDTLNIHKLLRYIKVSKIAYKIDTYNQALKEEESSKNENPIKETHKKSVSSQPLLFKVSQFLYCLTNLTSEGQFFFEKNYSIKYMLLEPSKPFESILNQAKCVVLAGGTMEPMSEFLSNLLPEVPSKDITTLSCNHVIPKENLQTYITNQPELEFTFEKRMSPSLVNNHLFQFFVDLSKAVPKKGGIVAFFPSYQYLAHVIQCWKQNDRFATLNNVRKIFYEAKDGDDILSGYSDSVAEGRGSLLLAIVGGKLSEGINFQDDLCRAVVMVGLPFPNIFSGELIVKRKHLAAKIMKSGGTEEEASRATKEFMENICMKAVNQSVGRAIRHANDYANIYLLDVRYNRPNFRKKLSRWVQDSINSEHTTHQVISSTRKFFSMRSLNSR

CHL1

ATP-dependent DNA helicase CHL1

861 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (PubMed:10931920). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (PubMed:15020404, PubMed:14742714). Has a specific role in chromosome segregation during meiosis II (PubMed:15226378).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

98.806 kDa

MDKKEYSETFYHPYKPYDIQVQLMETVYRVLSEGKKIAILESPTGTGKTLSLICATMTWLRMNKADIFTRMETNIKTNEDDSENLSDDEPDWVIDTYRKSVLQEKVDLLNDYEKHLNEINTTSCKQLKTMCDLDKEHGRYKSVDPLRKKRKGARHLDVSLEEQDFIPRPYESDSENNDTSKSTRGGRISDKDYKLSELNSQIITLLDKIDGKVSRDPNNGDRFDVTNQNPVKIYYASRTYSQLGQFTSQLRLPSFPSSFRDKVPDEKVKYLPLASKKQLCINPKVMKWKTLEAINDACADLRHSKEGCIFYQNTNEWRHCPDTLALRDMIFSEIQDIEDLVPLGKSLGICPYYASREALPIAEVVTLPYQYLLSESTRSSLQINLENSIVIIDEAHNLIETINSIYSSQISLEDLKNCHKGIVTYFNKFKSRLNPGNRVNLLKLNSLLMTLIQFIVKNFKKIGQEIDPNDMFTGSNIDTLNIHKLLRYIKVSKIAYKIDTYNQALKEEESSKNENPIKETHKKSVSSQPLLFKVSQFLYCLTNLTSEGQFFFEKNYSIKYMLLEPSKPFESILNQAKCVVLAGGTMEPMSEFLSNLLPEVPSEDITTLSCNHVIPKENLQTYITNQPELEFTFEKRMSPSLVNNHLFQFFVDLSKAVPKKGGIVAFFPSYQYLAHVIQCWKQNDRFATLNNVRKIFYEAKDGDDILSGYSDSVAEGRGSLLLAIVGGKLSEGINFQDDLCRAVVMVGLPFPNIFSGELIVKRKHLAAKIMKSGGTEEEASRATKEFMENICMKAVNQSVGRAIRHANDYANIYLLDVRYNRPNFRKKLSRWVQDSINSEHTTHQVISSTRKFFSMRSLNSR

chl1

ATP-dependent DNA helicase chl1

844 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

96.204 kDa

MCHSKEVKFKTNFHHPYTPYDIQLEFMRSLYSSISDGKIGIFESPTGTGKSLSLICASLTWLDEHGGVLLEDNEKSNDNKSNTSSKIPDWVLEQDLKIQKDLVKETHARLEQRLEEIRKRNQSRKNQMSNNSTTYHRETKRRNINAEASTSDNCNNSNTSVDPMDEYLVTAEYTMPSTSEQSEDLFNNGYSSKVSELLRKLSPDNEKPPIVQKIYFTSRTHSQLQQLVQEIKKLNNQTFSTPIRVVSLASRKNLCINNEVRKLRPTSALNEKCIELQGSAHKCPFLQDNTQLWDFRDEALAEIMDIEELVELGQRLKVCPYYGTREAVDSAQIVTLPYPLLLQESARNALNLTLKDNICIIDEAHNLIDAICSMHSSSISFRQVCIAETQLQQYFLRFEKRLNGNNRMHIKQLIKVVYNLKSFFLNCLETNTNSKVINVDSLLVSNGADQINLHHLSEYLNVSKLARKVDGYTKYMHSLGTQELESLNDLRSERFSNGNGYEEDPYTPVLMQLESFLLNIANPAPEGKLFYEKQTGDNPYLKYLLLDPSKHVEILTEQCRSVNLAGGTMSPIDDFITLLFSDEQSRILPFSCDHIVPPENITTILVSQGPAGVPFEFTHKRKDDENLLKDLGRTFQNFISIIPDGVVVFFPSFAFLQQAVKVWEMNGITNRLNAKKPLFIESKDFGDNPLDTFEHYKQSVDAGLSGMLFSVIGGRLSEGINFSDKLGRAVMVVGMPFPNSQDVEWQAKVSYVEEKAKEKGINAKQASQEFYENTCMRAVNQSIGRAIRHRDDYASIILLDSRYNRSSIQRKLPNWLSKNIHSSPNFGPAIRQLATFFRAKKMCD

CHL1

ATP-dependent DNA helicase CHL1

842 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

97.275 kDa

MVSESCSRNYNHPYTPYDIQIQLMDAIYNTIENGYKIGLFESPTGTGKTLSIICSSMTWLRTFKRNNTFLETNNEVEDVYESESEEDEPEWVKKAYQSSIVNRSKNKLIEYEHYLDKIEKEHAQNKRKEEELEIKVHKRRKAMTAAGTDLSEESYLPMDYYSDSEVGKIEDQNLAITKEINRLLKKVENKEEVSYINECPIKIFFSSRTHSQLNQFSSQLRLTNFQASFEDLEERTKYIPLGSRKQLCINEKVRSKGNDQSVNDACLDLQRETNGCQYLPKNYMMSSVTKEFADLSLAKIRDIEDLNELGIELNICPYYSVRKGIEMTEIISLPYQMIFQDTTRKILNLDIKDSIIIIDEAHNIIDVITSMYSIKITSDQLNKVIKSLKIYLNKFLKRLNSGNRINLMKLIKICQILLKFLNTNSEKVKSGDEVQIQDIFKDSTGDLVNIHKLDQFLTKSKIAYKIESYIEKTEMETDNGEKKGRITNSGGSSSSSSSSNPLLFTIIKFLRTLTNLSKEGKFFWDNENGTISLNYMLLDPSAVFKEIVDQAKCVLLCGGTMEPMSDYMDYLFPSVPTNKINTFACGHVIPKENLQVFPISQWNDTNFEFSYQKRNDSKQLMALGEFLIEITKRVPYGVVIFFPSYKYLDQVLQFWRDTKILTSIESEKTIFREPKDPSNVEKVLNEYGYLIQTERKGAILFSVVGGKMSEGINFSDDLARAVIMVGLPYPNAYSGEMVTKRKYIETSELSNGGTTTDAKEKSRNYYENLCMRAVNQSIGRSIRHINDYSIIYLVDRRFSTPRIQNKLSQWVKERISITTTNNNNNNSIYIMESTTDFFNIIR

CHL1

ATP-dependent DNA helicase CHL1

835 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

95.266 kDa

METSICSPENRYSHPYKPYDIQIQLMDAIYDTIDNGYKIGLFESPTGTGKTLSIICSTMTWLRDYKRENVFQPMAGLDGSDTDDSDSDDEPEWVKKAYRDTIVSRSENKMVDYEMYLEKIQNEYENNIQTAGSIKSSRPPKKKRSTAKKQELHDEDFLPEDYYSDSEVKPNADKLTVLESEISQLLDKVNGRTDEIEMTNDCPVNIYFSSRTHSQLNQFAHQLALTKFQSSFKGVEERTKYLPIGSRKQLCINEKVKSFSKNDSNINDVCVDLQKSKEGCQFLPKDYLNSSLTKKLSDLSLSKIHDIEEIADLGSNMKVCPYYSVRKGVEMTEIISLPYQILLSESTRAILNLQIEDSIVVIDEAHNLMDTITSMHSVCITIGEMNSIIKALKFYLGRFLKKLNSGNRIHLMKLIKLCQLVISFIQKSEKCNNIKVGNEINTSDIYQNSTGDMLNIHILEAFLAKSKIAYKIESYMEKVAENENEQAKTSSSNPLLYKIVQFLKCLVNPSKEGKFFWDSTNGITSIKYMLLDPSSVFKDIVSKARCVILCGGTMEPMSEFKNFLFPYVEDKKIKSFSCNHIIPPDNLKVYPVSSQNNVTLEFSFDNRNNPLMIEALGASIVRICQSVPDGVVVFFPSYKYMNHILSIWKSTDVLTQIESQKKLFEEPTSASQVQTILADYANTIKEEKKGAILFSVVGGKMSEGINFADELGRAVVMVGLPYPNAYSGEIIAKRKFIESEAIARGCSMSEAQRNSQSYYENLCMRAVNQSIGRSIRHINDYSIIYLVDCRYQSSRIQNKLSSWVRKRIETRNYNMDQIMEETRDFFMCKTIARLA

CHL1

ATP-dependent DNA helicase CHL1

830 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

94.515 kDa

MDNATKFHHPYSPYDIQLDLMQCVYDTLANPVKKVAIVESPTGTGKTLSLICSTLTWLRDNKADILSSVDTLHSNEDDSHDSEPEWVKDTYKESILKDKLELLDEYEKYLEELHLKENKIIKFGTSIEDKSKVKRRKVTSSSKAKIEVSIEDEDEFVAKPYESDGEETTDLEKKEALSKEVQELLAKFDSSKKNTDNVELGRFASASQNQVRIFFSSRTHSQLNQFAEQLKLTNFPSSFPDKVAHERVKYMPLGSKKQLCINPDVKKWKTLEGINDACSEVRRSKEGCPFYQNTPKWHNSKETNHFRDQVFSDIHDIEDIAKVGESLAVCPYYAARDFIPSSEIVTLPYQYLLSESTRSQLRLDLKGSIVVIDEAHNLVDTINSIHSAEISLSELKQSYNSIILYMKKFKSRLNPGNRVNLLKLSKLITVLINFITTHYKKPGLEVDAFSILESNNTDMLNVHRVLKYIKTSHIAYKLDTYIQKLQEKESPSNQKPSSQPLLYKISKFLECLNNTSSEGSFFFERGPSLRYMLLEPSRIFQDIIDSARCVILAGGTMEPVSQLLQYLVPKLDDSSITKFSCNHVIPDSHLRTYIVNEPQFEFTFEKRNSVNLVQNHLFNFYLELSTTIPKTGGIIGFFPSYKYLDEIIVSWRKAGLFEKLDKERKVFYEMKDGPDPLPDYTSAVANSEGAILFAIVGGKLSEGINFGGNLCRAIVMTGLPYPNVFSGELIISRKHLEEKVLNGGGSKTDANMAAKEFFENICMKAVNQSVGRSIRSINDYSLIYLLDKRYANANIQSKLSQWVRSRIQSVSTVRDVMASSKEFFDQIADT

CHL1

ATP-dependent DNA helicase CHL1

829 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

94.536 kDa

MLMSFNHPYQPYEIQLQLMQCIYGALSSGKKIAILESPTGTGKTLSLLCSSITWLRDNKLHLLSQNLNNGGIAINSSIELSDDDDFSDDEPNWVNESYNSSILDNKLLALNDYEKHLDTIANKHYKIDKNLIGNDNNNNKVKRRKIEHIPVGFEEDEFLPQDYISDSEELEQTKSEALSNEVKALLAKLDSKSNDEQTTSTELLQELNPVKIFFASRTHSQLKQFASQLKLPKFKSSFDEKFVSNERLKYLPLGSRKQLCINKSITSKWKSTEAINDACKELLQSEKGCPYHNKNTSNTLFRDHVFTGVHDIEDILALGESLNVCPYYATRDSITSAEIITLPYQYLLSESTRDSLNIDLSNSIVIVDEAHNLIDTINTIHSSHISLQELKTCQIGLQMYFAKFKSRLNAGNRVNLLKLIKLLDILIEYINKNFKKSGQEISANEIFNNTNADTLNIHKLNQFIKVSKIAYKIDTYLNSLSKESDNENNEESKNKSTPLLFKVASFLSSLTNPNEEGKFFFEKNKSIKYMLLEPSQSFKSILDEARCVILAGGTMEPISDFFDNLFPDIIKDKSVTFACDHVIPDDNLNTYIIEEPKFEFTFDKRQNPELVNKHLFQFFIKLSVNVPPTGGIVAFFPSYSYLQFVIDNWRSNGLFDKLNKIREIFYESKNGSDPLDEYIKVIEARNPAILFAVVGGKLSEGINFQDDLCRAVVMTGLPYPNVMSGELLIKKNHIETKILKNGGSKADVSCATKDFFDTICMKAVNQSVGRAIRHIDDYSNIYLLDQRYSNSKIKDKLSQWVRKRIQPETNLELIMEKSNRTFQTKKTSN

CHL1

ATP-dependent DNA helicase CHL1

825 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

93.77 kDa

MNRDDPRLTYNHPYKPYDIQVQLMDAIYDTIQNKYKVGLFESPTGTGKTLSIICSSMTWLRNYKKTQDHSTMGSNSSNDNDPNQTSDSDEEPDWVKEAHIKNIRSRTSGLAIDYERHLEELSQTPHAGHTVELGQRTHKRKKRATNDDDFLPDDYNSDTDSNSVETKNAKLQQEINQIMKRVDGSDGKTPGFVNTCPVTIFFSSRTHSQLSQFAHQLSITSFESSLGEIAERIKFMPLSSRKQLCIHPKVSSLSSVSAVNDACVELQQKSDKRCEFMPRVNNPESDQLVQRFADYSFAVIKDIEELHELGADLKVCPYYASRRNIENSEIIALPYQMLLQQATRKSLGLSIKDSIVIIDEAHNLLDVISSINSVSITRKELSSVIASLKLYYNKFTKRLNSGNRIHLMKLIKLCSLVETYIKNCEIQNKCVPGSDVLIDELFQGSTGDLLNIHRIEKYLDKSKIAYKIQTYIEQSREESDEKQASSPLLFKVTAFLKSLVNPSKEGRFFWDKINDDTEIKYLLLDPSEMFRDVVESARCVLLCGGTMEPVEDYYRYLFPYVPGEKIKKFTCGHIVPQENIEVLTVSSRKTTVFDFSYHKRNDPSMLRELALSLQDICERVPNGIIVFAPSYKYLNQLISTWRKDGNLAKISTLKQVFLESSDSTSIESILRDYGAAARGSGAILFSVVGGKMSEGVNFSDELARAVIMLGLPYPNAFSGELIAKRKFIEETTLSKGGTQAMAKKNSREYYENICMRAVNQSVGRSIRHANDYSVIVLFDTRYNSSHIQSKLSGWMRSSIRPERESFDMTLERIADFFAAKTLTKR

CHL1

ATP-dependent DNA helicase CHL1

820 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

94.146 kDa

MGNLEANDVGNNSRKYNHPFEPYDIQIQLMDAIYDAIDNYKIGLFESPTGTGKTLSLICSSMTWLREYKKNSTFRETEDSESEDEPEWVKQAYQKTIANRTKVRAQEYERLLDDLSENYDVSKVSVLPEKKVKRQKPEQEQDENFIPADYYSDSELDSKYENDKLTSEINELLSRVDGPKETVEPVNDCPVKIFFSSRTHSQLSQFSHQLNMTEFESSLDNIPERIKFSPLASRKQLCIHPKISKLSNVSSINDACIDLQQSSKNSCEYIPKLHNTQSEEIVKKFSDLSFTKIHDIEDLGKLGNKLKICPYYSVRKGIDVTEIIALPYQMLLQDSTRSALNLNIDDSIIIIDEAHNLLDVISSIYSVSITSNELSDITKSLKFYLNKFIKRLNSGNRINIMKLIKLCQVLEKFISSNSKDGKIKHGDEIITSDIFEGTTGDLVNIHKIEQFLNKSKIAYKIESYMQKLNDSESIKNRSNPLLFKITKFLKCLTNPSKEGKFFWDKTNDSVSINYMLLDPSEIFRDIVKRARCVLLCGGTMEPMNDYTNYLFPYIPPEQIKKFSCGHIIPQENLEVFPIGNYNDISFEFSFDKRNNSKMIIELGHAILNIIESTPDGIVIFFPSYKYLNVVMNVWRQNKIIESLTKVKAIFQEPEDSSKVEKVLNDYSSTNKSEKHSALLLSVVGGKMSEGINFSDELARGVIMIGLPFPNIFSAELIAKRKFIEESTIAKGGTKSQAMVNAKNFYENICMRAVNQSIGRSIRHKNDYSIIYLFDQRYGSDKIQDKLSGWVKQKLFTRGRCTDFNQVIKETQDFFRQKLLG

CHL1

ATP-dependent DNA helicase CHL1

807 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

92.764 kDa

MGKNFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEKLNSKVDNDNLSDSTFSSSDDEPEWVNQFYNDKIMKEKSKSLQEYENYLEGLSMSNIKPVLRQLDIGDRKRKKTVPRHIEIEIEDDETNFLPEPYEQDSVSNQNDYEKGQINDEIQKLLAKIDKGYDVKTENNMELKSPLKIYFSSRTHSQLTQFASQLTLPSFPPSSPTLEKERIKFLPLASRKQLCIHAKVSKLKSDLINDACVETVKRQECQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCEISLSDIKICKKLMKIYLNKFKRKLNGKNRVNIMKLMKLLDILQAFIESHFEKGKEISPQSMFRDSNADLLNIHELVTYMRGSKIAYKIDSYADSKLKSDESNTNSVKQPILFKISKFVLSLSNPSFEGSFFFEEGMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPFVPSKDIVQFSCNHIIPESNLDTFIVSEGFNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSDILPQYSSTILDKKKGAFLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVKSELKTSEIFAQTSVFFASNR

CHL1

ATP-dependent DNA helicase CHL1

803 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

90.691 kDa

MENTKRREFSHPYTPYPIQVDFMEALYDCIESYKVGIFESPTGTGKTLSLICGSMTWLRKNKAQLAVSTASADENEPAWVLEQTIQLAREEFSRNREMLQKRLDKMRRKNMRARISYEQGFKRAKKAPEPVDDSQFLPEDYSEVIKPEVQRLLSALAPPVENDFQEPVKIIFASRTHSQLSQFVGQMQHTTFPPSSDLQDLESTKLISLGSRKQLCINPRVSHMNSVQAMNDACRDLREGKKGGCKYYKNPHDALGKVDINTFRDTTLAEILDIEDLYKLGKHTSTCPYYASRASIPASEVITVPYQILLSRSARKAIDLPVKNSIVIIDEAHNLLDTITSLHTMSITKSQVSSASSGLQKYQHKFQNRLNSGNRVNLGYLVNMLQALEVFFEKAQKFHKKETAPGTPVTTSSLFDGSTADLINVNRLEKYIDESKIVFKIESYLEHVNGETQEKSHSSSLVLSSVMEFLRQVNNPDSEGVLCFDGPTKLKYQLLDPSEPFKDIVENARCVVLAGGTMEPTGDYLEYLLPYLSQDQIKLFSCGHVIPPQNLSVQVIPNGPNYSFNFTFDKRNDEKMILDVAITLLVYSKIIPEGMVVFFPSYKYLEQVVAVWKKAKKDGKNIYEILNDQKRIFVESQHDSVEKTLSEYAEEVPKGAILLSVVGGKMSEGINFSDGLARAVFMIGLPFPNLMSAEIIAKRKYIEQSVSEKMKAKGVSAKEALEASKGAARDFYMNICLRAVNQSVGRAIRHANDYACIFLLDGRFGKPEIQKKLSKWMREGIREGSFKEALGEVQQFFASHEKN

CHL1

ATP-dependent DNA helicase CHL1

801 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

90.288 kDa

MGRCEFYHPFTPYRIQLELMQQIYGLLESGKKMGIFESPTGTGKTLSLICSTFTWLREHKAGYLQGSTGAQDSEEDSEDEPAWVKENYEQSVLADVTASMRAYEQRLAAVDTDLLVKGAAKRQRVEVAVERPDDGAEFLPDAYHSDVEERPSHAGGRGQLRKQLDADIKRLLRKLDEPDAADKSRLAANPLKVYFASRTHTQLGQFAAQLRLPQFPPSLAGLEQERVKFLPLGSRKQLCIHKKVSKVKSDGINEACMDAVSKSECSFFSAAREPDIIRQFQDQAFSTIQDIEDLVGIGNTLHACPYYSSRELIEGAEVITLPYQHLLLENARKTMGIDLRDSIIVIDEAHNLIDTINSIHSASISLTELRQCKLALQAYLAKFKTRLNSGNRVNLLKLIKMVDVLSQFIETQYKNGKRINDPNDIFMGTSMDVVNIHKLEKYMKTSKVAYKIDKYIQATTSNDLQDRGSRDIKQPILFKVASFLKTLANPSEEGQFFFENGHVLKYMLLEPSEVLKSIVTEAKCVILAGGTMEPVNDFFTQLVPYLAPTDVTTYSCGHVIPDDNLNAFIVSENFEFTFANREDIALIERLFHFIYQLASRVPFGMVVFFSSYKYIDFVVKTWTDRGLLSRLDAIKRIYHETSDGADVLKGYSETIQSEKKGAILLAVVGGRLSEGINFENELARAVVLVGLPFPNMFSGEMIVKQQHIKEKVIRNGGTQEDVNKAVREFYENICMKAVNQSVGRAIRHASDFANVYLIDKRYSGPRIQQKLSDWVRKRIQSASNIPKILSDTEAFFSGKGL

chl1

ATP-dependent DNA helicase chl1

782 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

88.226 kDa

MLEFAKRESARAVTEKRRALEARLEKIKVEEEKQRHATDHPKEARKRRRVDTSSGDPGPEQDDQFILDDYDSDADERMASSKKLSDISGLSTSTLELLERFKEQFSAPVEDEIGHEDDDVKIFYCSRTHSQLSQFSSELRRVKMPSSMPAELSTSDANTDEVQERVKHLTLGSRKNLCINPKVMSLGNAAAINERCLELQQPGIAAEKRCPYLPSKEDEGQILQFRDHTLATIKDIEDMGKLGKRMGICPYYASRSVLKHSENVLLKAQKIVTLPYPLLLQRSARDALDLSIKNHVVIIDEAHNLMDAICNIHSVTIRLSQLQTALLQLTTYAHKHKARLKGKNRSYIAQIIRLVSSIRDHLRSILGQNLPAEGTVDPSDLMAGKGVDQINPYKLSRYLQESKLARKVDGYVEFLKNKNQQSDDKPSSPVLFLVQSFLLSLMNPSAEGRFFYLKCHDDIQLRYMLLDPTNQFREIVEDARAVILAGGTMSPMSDYRNHLFSYIAPSRLDTFSYGHVIPPENLIAHTLVNGVLGSEFDFTYDSRDSEKMILDLGRTVATLCQAIPDGVVAFFPSYDYLSRIVAIWRKPLEGEKGETILSLIEREKSILYEGRDMGPKTDDLLQEYTRTIDSGQGALLLSVVGGKLSEGINFSDKLGRGVLIIGLPFPNIRSAVWQAKIQYVEQKTYNSSSGSEKDRQSIAKAAGKDFYENACMRAVNQCIGRAIRHRNDYAAIVMIDRRYEKANIQGKLPAWIKESMLRRSVRRPASALAADLSNFFSGRSPR

chl1

ATP-dependent DNA helicase chl1

731 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

82.217 kDa

MCQKYDTLSGDRDVEHDEHFVLEDYDSESEDQNISSKSLGHSSELSMSTLALLERFKKQYSAPTEEEETVGDDEPKIFYCSRTHSQLAQFASELRRVEMPPSLPKELSEKLTDSEALEERVKHLSLGSRKNLCINPRVMKLENATAINERCMDLQQPGMAVEHRCPYLPSKDDEPQVLQFRDHTLATVKDIEDMGKLGKHIGVCPYYASRSVIKHSEIVTLPYPLLLQRSAREALGLSIKNHIVIIDEAHNLMDAISNIHSVTITLSQLQTAIFQLTTYARKFKTRLKGKNRTYIAQVIRLVSSVADHLRSIQGSNQPPDGAVKTSDLMAGKGVDQINPYKLSHYLQESKLARKVDGYVEYSKDTANRQSHGKPSTPVLFHVQSFLLPLMNPSAEGRLFYMKDQNDIQLKYLLLDPTNHFREIVEDARAVILAGGTMSPMSDYMNHLFPYVPASRLDTFSYGHVIPPENLVAHTLAQGVMGCAFDFTYESRDSEKMIIDLGRTVATLCQAIPDGVVAFFPSYDYLSRILHIWKKPLGADKNQTILGLIERKKPILYESRDMTTKSDDILQEYTRTIDSGSGALLLSVIGGKLSEGINFSDRLGRGVLIIGLPFPNIRSAVWQAKLQYVEQKAYSGSSGSETDRQMIAKAAGRDFYENACMRAVNQCIGRAIRHRNDYAAIVMIDRRYDKPNIQGKLPAWIKQSMVRSPTQRPAGATVQNLIKFFAARGSLD

chl1

ATP-dependent DNA helicase chl1

721 amino acids

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

80.623 kDa

MEPQAEEFHHPYSPYDIQLQFMRALYSCIEKGKVAVFESPTGKLAGLSTGTLELLKRFQHKSSAHPRQDEDYGDEDIKILYCSRTHSQLTQFASELRRVNMPSSIPKDFSEGVADTDGLQEGVRHLSLGSRKNLCINPRVSSLDNVTAISERCLDMQQPGVAAEQRCPFLPSNENEAQVLQFRDHVLATVKDIEDIGKLGKDIGICPYYASRSVTKHSEIVTLPYPLLLQRSARDALDLSIKGHVVVIDEAHNLMDAISNIHSVTITLSELQTSLFQLTTYARKFKTRLKGKNRNYIAQVIRLVTSITDHLKTILETSQAPEGPVQPSDLMSGKGVDQINPYKLCRYLRESKLARKVDGYSEFSRERADRQADRKPSTPVLFHIQSFLLPLMNLSAEGKLFYIKAQGDIQLKYMLLDPMNQFREIVDDARAVILAGGTMSPMTDYIHHLFPYVPSSRLGTFSYGHVIPPENLIAQVLGKGVTGTEFDFTFETRDSERMVIPDGVVAFFPSYDYLSQVLSIWKRTLAGEKNRTVYDLIEGKKTILHESRDVTISTEELLQEYASIVGSGRGALLLSVVGGKLSEGINFSDRLGRGVLIVGLPFPNIRSAVWQAKIHYVEQKAYKESSGSDANRQLVAKAAGKDFYENSCMRAVNQCIGRAIRHRNDYAAIVLMDRRYDKPAIQGKLPAWIKQSMASSSALRPAGATIGSLSKFFVAQRTSKT

CHL1

Disease resistance protein CHL1

459 amino acids

Confers resistance to low temperatures by limiting chloroplast damage and cell death, thus maintaining growth homeostasis.

51.655 kDa

MSSASSSSAASLLLGREVDVFLSFCCQTSHGYFQNILIRNGIRTFLSYRCLEKRFGPIGQRTLKALEESRVAVVMTSTTKPCSVGFLEELLVILEFQEKGSLMVIPIFLTDLSFNVEEICRQHPEKAPSWRTALTKLTNLAAEYPLSQNLAGMDQSDLLNQIARDISLVVFYSGSNDSNALVAMDRHMKVVYDLLALEVNKEVRTIGIWGSAGVGKTTLARYIYAEIFVNFQTHVFLDNVENMKDKLLKFEGEEDPTVIISSYHDGHEITEARRKHRKILLIADDVNNMEQGKWIIEYANWFAPGSRVILISQNKNLLVDAGVMDVYEVRSLRYDEALQVFSHFAFKQPYPPSDFEELAVRAVHLAGFLPLGLRLLGSFLAGKGREEWVAALLKLKAKQGGHIMEVWKLMEATDDKGLEEWETAADIVERKESSQDKSQQESEVAADILIGKESSQDKQ