Protein
Adenylosuccinate synthetase
Organism
Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)
Function
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
Similarity
Belongs to the adenylosuccinate synthetase family.
Sequence
MATIILGSQWGDEGKGKLSDILCQKARVCARAAGGHNAGHSVVANGVSYDFHLLPSGLVNPQCTNLIGSGVVFNVQAFFKELAALEEKGLSHARKNLLVSDRAQVNLELHARVDGLEERELAGNKIGTTGRGIGPSYANKAARNGIRVHEIFDQESFEAKLRRLAEGYKKRFGDLLEYDVEEEIARFRDYREKLPDFVVDAVNYMQAAQASGVDILIEGANALMLDIDYGTYPFVTSSNTGLGGVITGLAVNPRRINVAKAYTTRVGEGIFKSEDVGEAGKKLQDIGREWGVSTGRKRRCGWLDLVVLKYSASVNYYTAWNLTKLDVLDTFPTLKVAVAYKDPETGKELEYFPADLGYLERCEVVYREFEGWQTPTTAVKKFEDLPRQAQMYVRFVEEFTGVPVKWIGTGPGRDDMIYL