Protein
mRNA-capping enzyme subunit alpha
Function
Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate (By similarity).
Similarity
Belongs to the eukaryotic GTase family.
Sequence
MIQLEEREIPVIPGNKLDEEETKELRLMVAELLGRRNTGFPGSQPVSFERRHLEETLMQKDYFVCEKTDGLRCLLFLINDPDKGEGVFLVTRENDYYFIPNIHFPLSVNETREKPTYHHGTLLDGELVLENRNVSEPVLRYVIFDALAIHGKCIIDRPLPKRLGYITENVMKPFDNFKKHNPDIVNSPEFPFKVGFKTMLTSYHADDVLSKMDKLFHASDGLIYTCAETPYVFGTDQTLLKWKPAEENTVDFQLEFVFNEVQDPDLDERDPTSTYLDYDAKPNLIKLRVWQGSNVHTDFAKLDLSDDDWERLKALEQPLQGRIAECRQSTTKKGYWEMLRFRNDKSNGNHISVVEKILVSIKDGVKEKEVIEWCPKISRAWKKRENDRRQKHFNGVARPASVSHEEPLRKKIKTESNGNGHQTPPRQEQQQQSQQILNDIPTYEDSDDE