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CFD

Gene
Cfd
Protein
Complement factor D
Organism
Rattus norvegicus
Length
263 amino acids
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Similarity
Belongs to the peptidase S1 family.
Mass
28.442 kDa
Sequence
MHSSVYLVALVVLEAAVCVAQPRGRILGGQEAMAHARPYMASVQVNGTHVCGGTLVDEQWVLSAAHCMDGVTKDEVVQVLLGAHSLSSPEPYKHLYDVQSVVLHPGSRPDSVEDDLMLFKLSHNASLGPHVRPLPLQREDREVKPGTLCDVAGWGVVTHAGRRPDVLQQLTVSIMDRNTCNLRTYHDGAITKNMMCAESNRRDTCRGDSGGPLVCGDAVEAVVTWGSRVCGNRRKPGVFTRVATYVPWIENVLSGNVSVNVTA

Gene
Cfd
Protein
Complement factor D
Organism
Rattus norvegicus
Length
263 amino acids
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Similarity
Belongs to the peptidase S1 family.
Mass
28.442 kDa
Sequence
MHSSVYLVALVVLEAAVCVAQPRGRILGGQEAMAHARPYMASVQVNGTHVCGGTLVDEQWVLSAAHCMDGVTKDEVVQVLLGAHSLSSPEPYKHLYDVQSVVLHPGSRPDSVEDDLMLFKLSHNASLGPHVRPLPLQREDREVKPGTLCDVAGWGVVTHAGRRPDVLQQLTVSIMDRNTCNLRTYHDGAITKNMMCAESNRRDTCRGDSGGPLVCGDAVEAVVTWGSRVCGNRRKPGVFTRVATYVPWIENVLSGNVSVNVTA

Gene
CFD
Protein
Complement factor D
Organism
Bos taurus
Length
259 amino acids
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway (By similarity).
Similarity
Belongs to the peptidase S1 family.
Mass
27.878 kDa
Sequence
MADRSLHLVVLILLGTALCAAQPRGRILRGQEAPSHSRPYMASVQVNGKHVCGGFLIAEQWVMSAAHCLEDVADGKVQVLLGAHSLSQPEPSKRLYDVLRVVPHPGSRTETIDHDLLLLQLSEKAVLGPAVQLLPWQREDRDVAAGTLCDVAGWGVVSHTGRKPDRLQHLLLPVLDRATCNLRTYHDGTITERMMCAESNRRDTCKGDSGGPLVCGSVAEGVVTSGSRICGNHKKPGIYTRLASYVAWIDGVMAEGAAA

Gene
Cfd
Protein
Complement factor D
Organism
Mus musculus
Length
259 amino acids
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Similarity
Belongs to the peptidase S1 family.
Mass
28.057 kDa
Sequence
MHSSVYFVALVILGAAVCAAQPRGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGNMTS

Gene
CFD
Protein
Complement factor D
Organism
Sus scrofa
Length
259 amino acids
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway (By similarity).
Similarity
Belongs to the peptidase S1 family.
Mass
27.764 kDa
Sequence
MADRSGHLAALILLGAAVCVAQPRGRILGGQEAKSHERPYMASVQVNGKHVCGGFLVSEQWVLSAAHCLEDVAEGKLQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLKLSEKAELGPAVQPLAWQREDHEVPAGTLCDVAGWGVVSHTGRRPDRLQHLLLPVLDRTTCNLRTYHDGTITERMMCAESNRRDSCKGDSGGPLVCGGVAEGVVTSGSRVCGNRKKPGIYTRLASYVAWIDGVMADSAAA

Gene
CFD
Protein
Complement factor D
Organism
Bos taurus
Length
259 amino acids
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway (By similarity).
Similarity
Belongs to the peptidase S1 family.
Mass
27.878 kDa
Sequence
MADRSLHLVVLILLGTALCAAQPRGRILRGQEAPSHSRPYMASVQVNGKHVCGGFLIAEQWVMSAAHCLEDVADGKVQVLLGAHSLSQPEPSKRLYDVLRVVPHPGSRTETIDHDLLLLQLSEKAVLGPAVQLLPWQREDRDVAAGTLCDVAGWGVVSHTGRKPDRLQHLLLPVLDRATCNLRTYHDGTITERMMCAESNRRDTCKGDSGGPLVCGSVAEGVVTSGSRICGNHKKPGIYTRLASYVAWIDGVMAEGAAA

Gene
Cfd
Protein
Complement factor D
Organism
Mus musculus
Length
259 amino acids
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Similarity
Belongs to the peptidase S1 family.
Mass
28.057 kDa
Sequence
MHSSVYFVALVILGAAVCAAQPRGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGNMTS

Gene
CFD
Protein
Complement factor D
Organism
Sus scrofa
Length
259 amino acids
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway (By similarity).
Similarity
Belongs to the peptidase S1 family.
Mass
27.764 kDa
Sequence
MADRSGHLAALILLGAAVCVAQPRGRILGGQEAKSHERPYMASVQVNGKHVCGGFLVSEQWVLSAAHCLEDVAEGKLQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLKLSEKAELGPAVQPLAWQREDHEVPAGTLCDVAGWGVVSHTGRRPDRLQHLLLPVLDRTTCNLRTYHDGTITERMMCAESNRRDSCKGDSGGPLVCGGVAEGVVTSGSRVCGNRKKPGIYTRLASYVAWIDGVMADSAAA

Gene
CFD
Protein
Complement factor D
Organism
Homo sapiens
Length
253 amino acids
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Similarity
Belongs to the peptidase S1 family.
Mass
27.033 kDa
Sequence
MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA

Gene
CFD
Protein
Complement factor D
Organism
Homo sapiens
Length
253 amino acids
Function
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Similarity
Belongs to the peptidase S1 family.
Mass
27.033 kDa
Sequence
MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA