CFAP61

Cilia- and flagella-associated protein 61

1699 amino acids

As component of a spoke-associated complex, regulates ciliary mobility by mediating a stable and functional assembly of the radial spoke 3 (RS3).

198.392 kDa

MYSNNQLDNPNHSRSQYRNGDQSGIYAGSDEEFQVLVRKSDLDDVDEVLKIIAQHEREANDLLYDYPNLLSLFEKNYLSVTILNQQQQIIGAAVFNDFPQGLTGQIDFQHENFWENWIFDAFNFDESICITPFNTLWMTFFFVAKDQYKFSQEEELIICQKVFQNVYATLPQLEGILFLKRGETMEDNGAQAQISSILENIFIEVPVKDRDIIKRVRGIHLNSEVFYSPKHACQEIIEIRMAREQDHDDLAEIFNRQSEVLTAQFGEFFIADLIATQNLTRRGTRKFLNNGKAIVGQVRDKAVGLMSISTDIDYKFLAQCFELETYDNLFKPDFMEAIQNKRDDIRRENQYREEDQYQEIVKKMNEERMKSHFIGQRMTLQQHCREKEQEIVMKIDEIINNDAIQKNLTKKQVEEFLDEWLRGYELHQPSDLFYQYPHIFPNTQSIILTPRQLLIETLEFFGLPQHYMNGAGHWKDWVQKKMEEKRIAQLKRPQKKVTKRPKRQKEEDKKEDEFKPPSYFDLTPFQSAFKKFLAVNPEGRTIFRQKIEASMKVIKMMFCNENGEMKEERHVDLNDLGNELNKQKMDIAPEVCENLASFLECFGEIKYEEEIIMVNPPKEDTNQNAKIAQTKKMFASEQTESKPIPKLLKKTSFQEFFDAVYKMKEFDIMMNRLDITKSTTLKAEVSQIVKEEAQQEKAKQEKRRIERSPNPYDDYVKNLKDLDSIPEVPIDAQNAIVINLFCIDENFESRSLDFVEYAFSIFGDRDYIILTQPFTVPETTLLQQFIKIPMKKNSTFDHVLYIYHKDCLLSNTLFIRKSKLEDMQYVAPLFSNLINKQQIYDDTLEAITQTASRKVAFSVFCDQSLIGIYVVSKNVNLDYYISHFCVQDHIILKEHPMTCHTKLIHTALNPLFTKNTRFILKEILRLMNKTCMYFEVQEKTLLPDVFNELVFVRARQFPHFLKRKWDFEHDKEHFERAGDLTEVQDGKRDAFDQEQAPFSLSVITKKMMSSVKVNNNTRIVVVGASDTGISFIESLLSVKDINFTHITLLAPGGIMTMHINLPGDQLKALSTNYTLEELKNLMLDARVNVLDAKMVELDKKGKKIKLDKNAELPYDYLVNTVGLIDTELQNRRLISTGLFSSPYYQQLLDKYGRDRAQIEEGAPPIFGQHPVYGNYVQGVYSIDDPYLYEEFKKTGKKDSNIDLLTRKKRPQSITIYGRTLHTIAFISGMVNRGVHPNRIHYVIPPKVFETQVQFKNNTERLIYEDKRINDPDPFDDPSVEQKIFEFMESKGIQVHKGYNLHQIDVDEETRICQGVVFRKKADNYEEIIQQIEIKKQQILERDANSENADKGFDDTQSRDGDEENQPITLEQEIEELERNKFDDIEITSRFLVTSGLVDIDKEIFYIIHENGLVYNGRLIVKSNFQTTEKDIFCCGKICEFSQRYKRLSIGRSLRLDKYNGRELGQKLAKCLLDSLDLGYLTDQIYSLGELPNLYMPIGIGAFLPGDLFYYHIKKNDYARPSKTMEAEDNRQDIVSDNIDQKQQIGHYIKFKFDNNGIIDQVTYLGTEPVSVQSLVSFVGLSEKCLNQLDVRFKNGLIPNISEFLSENWAIGLYHEWFSEFRHITKMEMLQSENIQQILDEAAKYAQGGGFLDPEFIEKIKAKISPEIISQIQQGTLDFIRENQNHLPMYYVPPKKVNVD

Cfap61

Cilia- and flagella-associated protein 61

1252 amino acids

May regulate cilium motility through its role in the assembly of the axonemal radial spokes.

143.289 kDa

MSILTSPRGKVEVVHCRRTESQDIFCIKNLVRKFTQKLFGRLNIIYLLEKANLAVTVCNDKEEIMAHSIFLDYPNWNVAKQDNWIPLFRELDKEIPCTPLNTLFMHFFVAVDEYATGCLKEIIRTVFKAVPELYFIFLIVPTYLSLGSTLITVFDQVGNIPCLNYNEDFAVHICHRHNHYPQLHIRKARVEDHDDLMPIFMHYDNTLKEIYGEYFLAELIEAQDKDHHAVVCEVEGKAVGFMSVCTSVNLPLLHECFDLGPFHGFCTPHPDDILKPSREPSLEEGEEKHLKKCSTSLIIREMQIKTTLRFHLTPVRMAKIKNSETETSASCEEALPTVLGLVSEERLKQDMEKNLSILSLVDEEDVASSLSSSLLLSVESSHFRPLYLGDPIAFCIQLFCIDERYEARQVLISNVSLSLDFMSFVFSLFPGKNFCLISVPHLTPEFVLIQNFVKVVPFNNCTLDHDLYVFHRAGLLRSITIRLAKFLDTAGVEKLVSTLLLSTKILDDLAQYNEAGRDPDGTALQVFVAEVADQIVGIAVIRKEMDIEYIRSHYNIEDFIYFSHHQQEEHGRLNHFALNPIFRHYTKFFLKEILRLGYKSCLYYPVYPQTREGKLQSSYSHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKEVSKDQVSFALNHTNRKLTLEPKVTVNARIVVVGASSVGISFLETLVFCSHLKFNNLTLISTHGLPGKRLLHNEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTAIDRAAKQVVVSKSEIVFYDHLILCTGLQYQVPCPTGADTEQHLTNREVLELSKQRYTGTVPSNLFILNDEEDCVRMLCWLRNSSILTEGKVIVYGNTLDAYTTVETLLNIGMKGSGIYFVHPPTESNITCINNNDVESAVEDALSAAGVTVFHDALLAQWNHGQHPDPIYNACFTTSTKPIRLECSAFFSFYKKNVDYETFKAFNDACLVYDGRLVIDTTFHTNDIAIRAAGSLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLSLFDPTLEPVTEPPADLDRLIPMYKGAKIQGGILPGSYHYLHISKPAIPTPLNLQRSQPDFGSDVVTGNAKKGTYFRLYINNYKLVEAITCFSKEPFPSSNYIRLFGQHEQVLNNLCTRFDDKLIPDLYSYFTEPWCMALFHDRFIDLKKELRQILISKQEEDKPTMEEIAYRLEEEEINLNEKPQKYLQRVFEDSIYKSLLEKSILDYLHYNQYHLPMYAWPGII

CFAP61

Cilia- and flagella-associated protein 61

1237 amino acids

May regulate cilium motility through its role in the assembly of the axonemal radial spokes.

141.349 kDa

MSVLTSPRGKVEVVHCRRTESQDVYCIKSLIRKFTCKLFGKLNIIYLLEKANLAVTLCNDKEEIMAQATFLDYPNWNVAKQDDWVSVFRELDSDIPCTPLNTLFMHLFVAVDEYSVGCCKEILRTVYKAVPELHFIFLIVPSYMSLGSTLITVFDQVGNIPCLTYEEDFAVHICHRHSHYPQLHVRKARVEDHDDLMPIFMRYDTILKETYGEYFLAELIEAQDEENHAVVCEVEGTAVGFMSVCSRVNMQLLHECFDLGPFHGLCFPHPDDVLESPQDLSVRRSQDAELRSSSQGSQKIVEELQEPVSPDTMENIQGNIAREAASEEALTAVQSGNVSEPEDIEKLSDISTGYAQYHHVSSRSLASLVLPEEPVHFRPIYRGASAAFCIQLFCIDEKYEARSLDFMNFVFSLFSDKNFCVISLPHLTPEFFLIQNFVKMVPFNTCTLEQDLYVFHRAGLLKSINIRFATLLDTPGVENLVSTLMLNKSILEDLDRYNKARKDPDGTLLQAFVAEVAEQIVGIAVIRNEMDIEYIRSHYNIEDFIYFSHHQREEHGHMHHFALNPIFRHYTKFFLKEILRLGFKSCLYYRVYPKSREGKFQNPYAHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKAVSKDPMSYALNHTNRKLTLEPKITVNAKIIVVGASSVGISFLETLVFCSHMKFNNLTLISTHGLPGKKLLDTEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTGIDRAAKHVVLSTDEIVPYDHLILCTGQQYQVPCPTEADISQHLTNREVPNSSQRRYTGKVPCNHFTLNEEEDCFKALIWIRNNSITTEGNIIVYGNTIDTYTTVETLLNLGVSGSRIHLVQPPPASTITCINNYSVESAVADALGAAGVTMYRDAILAQWNDGLHPDPIYSASFTTPTKPFRLQCSMFFSFCEKNVDYETFKALNDACLVYDSRLVIDTNFHTNDIAIRAAGSLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLHLFDPTLEPVTEPPANLDRLIPMYKGAKIQGGILPGSYHYLHIAKPAIPTPLEVQMAQPNYGLELVTGSAKNGTYFRIHINKYKMVETITCLSREPFPASNYIRLFGQHEQLLNNLCARYDENLITDLYSYFTEPWCLALFHDRFIDLRKELRQILASKEEEDLPSIEQLAHQIEDEEINPTEKPRQYLKRVFEESIYKTLVERSTLDYLHYNRYHLPMYAWPGIV

CFAP61

Cilia- and flagella-associated protein 61

1147 amino acids

As component of a spoke-associated complex, regulates flagellar dynein activity by mediating regulatory signals between the radial spokes and dynein arms.

121.326 kDa

MSNITARQTLTRDVQSVDALVRQACKAEANATLLLGTGLLNLTAVDDKDTVVGYLSLDDVSCTRLGSGGPGADTWVQQAAASRFKLGSTAFVRVCATAHLSEIEASAALLRTAFLHMPSLQTLLMVAGGELSFTEPGLAAVFSRVGAHKESGAVLYEAGRDAVVPPLAIRPARVEDHDDMLPILQRCEVAFPALAKLPEASRPHEPFALTRVVAGQDERNRVLVAEAEGRLVGFIVMTSDVDTGSLAETFDLHAYDNFLPPEVYEQQYEAARDSVRGQKLAMLRHQRQQEKEAEGEGAGEAGGQGGNGGVSAGMQTDPEQGEDGEGAAEGEGEGAGEGAGEGGAAAPGTGADKADDSEEAEAQLLAAAEPTDEETRAEMLAMFAGQAPPADPTLFAVTMLCMDPAFEAQAIEFLTPAFAAYTDKLYCVVTLPHDSREPALMGTMTRVAPNPGSLFPEVLFMFHRHALIPDFAVRLGEPGDLDAVASLVAGMPNADDIVASFSGAAAAGSAAVALCQGELVGLVTVNPEVDLELLQANFGLSNHVDLGYQPREQHGEIDMYTMNPIFVHRHRTLVAATMRLLGKTALYYALPPGQQPPDMLEVLEQVAPRHRTASDKQLQAEFALYVFTRQAAFKRRRSVNSQIVVVGASECGLAVVERLLLDPELQFNYLTLLAPGGIKVGGMACQFTAGVIARLGLEARVMLLDAEVIGLDRGSKLLDLSDGSQIFYNQLVLAAGLQDQSRYRFAEADPEVAGLLVTELELAADFSMNDAMVMNSILVYGNAMGAYHSLAVLEAKGAGEKTRFVAPPGQQPPLVGVLHALAGEAGVALPSPEPRDLAGLSVVQPVGPELHASATLIDPADPGPREELPVDLVVGCEPPSVSRSLFTCLNDASLVFDGRLVVDGAFRTNDPAIYAGGSLAKLSRRYGGTHLEHYNSRDVGSRLASSLVSFFNAGPDEPQPAATAAAPPPALHRARAVGCSLPGGNYFVYAGCPAALQRPSTAAPEGGYEMKTASERGLTRITLDGEGRVHSLMYLGRVAVNAPRLGSLVGLHANYLNSLAPKYQAGDIKCLLSFITEPWSELLYNESFPELRETLLEVALAELSAGGREVDGGMVEWVTHAQDAVLEFARAHAAELPGYTMPSAART