CFAP54

Gene

Cfap54

Protein

Cilia- and flagella-associated protein 54

Organism

Mus musculus

Length

3106 amino acids

Function

Required for assembly and function of cilia and flagella (PubMed:26224312).

Similarity

Belongs to the CFAP54 family.

Mass

353.76 kDa

Sequence

MASSRSSSSSSEESPDSETSVSPVHLPPTPPPTSTAVLKSPSESKSSSTDPPQCTHSEDSLPSAAFYGPLDSKNPLLASCEKEIRELLGFMKKKKALATSMEQKYEFHRRCATTLFNIWTKYAPRLPSNYYNEKLLKVGDSLCQIKEYKLALLQCYGRYLQEFIADFDEHKEDVNHFKTVFFPKGFGDETARLTFHALSGKNICNYQLVCESDANLQNEESVRQCLHILSSFRLIMQVALPQEHLCWIIFNGTLYIYTICRKLMVIGQSSKALEFLLWASMCMESSVPLLSIRYLTWRATLYTAVCQCHYDCQDGIHGEAFARRALAKIDELRQLELMSSSSSLETSRKYYREATIKMAVMIFKRGVFESRRKNKNVLRPKLRLNLKEAQSLPWPRTVTERLLDELLDSTSSRFLAVLEALSDSNRRILQTGPLVTDEMELRDVVSELFMAGKELLILSNVRSNGKLDFPQTSLLEHVVEKRNALSVGASVRFAKLAFTYEEWGLFESLAGQLIHFLQKQDNPQSKKAEKDLILLLAVEPLINVKRNRGLIFPLETDKETQSIENYLKHIACHESCMRTTFTEDTFSLAAILHFCVCVPTQGVLPDKDIVVDIIGLLWQRCKLGIQRLNIPKNDFAKYSHKISTNKWVYLLWQISEVIHCYKLEDLDIVMVAEITLRLSEILESLGSPKRKFKKSADLSAKKGPDELPGTSKGVPEILPILKRAPVEQLFYAYELLDKAIIGMSWKCMLTTLSDGSSVIDHCYVKDSQDVDGDTYKPIASNSYTMDLHLELIQAQHRIAVVLLDQLEVLQAPTVSTNTPAKGWEKVKKPRSTECFTELTVMKKIKKNKLSKAIYLMQKALLLFEKDAVCETSRNLLMEANALIEKVEAEQNALYSYQKFLGSSKIKKSRIPPPPILLARTHCSVTLKPAPFISEVKASWYCILGCKADGSYGKVRLNNNHLPNSGEAIPADGRSFFEIKGLETNAQYCFAIAAYSSSGKLIGDAIGETTKPILIYPPLSAVTARMYLTQVAYQIGNYEMAKKVFSPVWDYFVASPLPDEQSVICLSNIMTITQKRLHSNILADTSSILLYLFLRNIFVMSDIKIKEENLFCDNIKGNEIFPAQQVARLVECENVLVALELSNFLNDANFALQAVTQCYGLLAPIIYHNIVLVPVIQILIKCIVVLQGIPSIIHSKKNISSFESIQHMIACCIFYMTKILRSWKEYDLAIMLINYGKKMLDITSGCRSLFGIEQEETAEEGVCSKKTSRTKKPQQVLLPEKINEQLALLETHLLKTTKQINSAELSGSEDPIFLYPIVLNWTVKGAMKEVMKFKQRPRFLEFFTQIMLKCMNDEKFHLMVEISAPVYDFLKRRNESLIGVKRIKYKETVISRRALKSPSKFKAIVIEIGKSSDLTRRRRKKKKTLKDFFYKNPSIFDMAELDRNKRTDVRKMAYRSLSDNLNPLILTYVRRKRFHQILLEELPWRAQMNLYLANAHFHLFLQKLTERTKERLGSSYSSVSFRSCDPNLFSLFHSGTVLPTAKLTVDSYNAMMDALTVSKKKKHNQTTDTEDLSVLFNSKSDDNIPKMKTQTIYESDSQLGIGVNVREKDRTLVWGLDHFMKIFLCCRRAMVLAYRGGYWTLLQNCCRVFWNFSRELQILLKQTVASCKTFPVSQDNFLCICVLPFYLGAELLIDMLIKLQSTNSIKPFEERGEFSIPSCYGNIKSDNGGSSLIFEHPLDDVNVVDLRWIHDFVLKSLEVLYQVEKWETLVSLAIQFNIISHERYTEQVTPLLVYAQRQLVQRIKELNGPELSRQACARYEAENGEKITCRNFIGKRLKIDSSTPKNLAELQGSSEPLKTLITSEQRLAKQLVSVPLDVNDTLRCFRETLEKSKYHNRSVRHSRKLLSLFLAQTQDVLQTSNQRSLKVQSLHSLGSLLLFADKKRAAFKCWSQALDDIFRKPDVLHNWKEFGTSLPGAPSSSSPPGFKDYSEEFLSKFGIWGCLQAAMITAKIAQFIKTANVKKRINCCILSALLFQSLLRTTLPHPKAERNYAQYEITQLLPGIELFSDKFRADICSVIASLYYVIRELHYAKYNLIVLPLLALYQYFVSVICQDIVRNLEARILKIEILIDLGFFSEAFYELFQIYHGKNMPCAIPAGYKATMKVKITQSFDSGKPLTHKDNMQALEELINRGLPHILVNLGYQHLLNKFNFAKSHFFISLAATINCIPDPSPKIMYYQFITERSKPTPQNLKDNENSHGQFLRLRDDYNLNTIKSILLMEAEEKVNSLLSETEHQCHRPLYLSSVLELEIMVEARLHLAAIALQRYRPAYSTAILYSTLKLLQDSKVFKKKVPEESCSPTSPETSTTESKDDSEFLDPISLNSREYFNIHLWLRCRLMLVTSFIAQIRGIGIMKESELTDCLSLIDEVCTEAKSADDTEVLAEFLMQAVVLGLQEKHFKADIIQKLKEIISLLEGSEFLSPRSWLTLAKSLILMDDLTKAEKFKKASSKENKLIFLNQAHRILIAQMLTFGETIEFPLSDSDYASPLQPLKNIYLPHVMLLAKVKLRIGHTMAKQVCSSSKKKDISKWLPVLHMFDMALKVCKATAAEEYEVEAEILFQKGRIERQMLMEEKTSIAHIESFFEAIQISLKNDQNSGLIRDSYLEIALVYFYLKKPKRKASATTLKPLPRRHSSVKDPVATQTEMYSSLAWIAIRAAAQVSESVLGINLLIGKKRAMIDKVNNITLPNIPEFATVDLLSSYTDYLLENYQVVFQTSNSLMCENDDVYDCIDGRKRNLSKVDVTWILLIRYYIHLQRINNMSKLLASATPVSGISLPDDTLLTSLYNSELILRQKEMHLFLKRFLQLYSSSCIDGFPRELLQGLENISLEKVLFESSGKVHRDSSLQSDLSGKLTVCPSYTEISSEMAVQALNKELCFQWYIPPLDKPLKDSEPMVLLLYAYNLKPLRILDIKVSTGNSLYVGTSWIPLRSVIAVHQKLSNLAQIAEISLPSVPEVTSEENIYETIEPEDKPIDTDLENMILECCSEIEALFSNNKDKDNEPPPPMTKVPFDVSLPAIFSLERLFDLANGCIVSVGSLFNWMVSIIQ

Gene

CFAP54

Protein

Cilia- and flagella-associated protein 54

Organism

Homo sapiens

Length

3096 amino acids

Function

Required for assembly and function of cilia and flagella.

Similarity

Belongs to the CFAP54 family.

Mass

351.97 kDa

Sequence

MAAQGSPSSSPSDDSTTSGSLPELPPTSTATSRSPPESKGSSRSSLLQWTCPEDSLPLAVFYGPLDAKNPLLASCEKEIQELLGFMRKKKALATTEEEKHEFRRRCATSLFNIWTKYAPRLPADYYNEKLLKVGDSLCQMKEYKLALLQCYGRYLQQFNTNFDENKVDVTQFKATFFPKGFKDKTAGLTFHALSGKNMCNYQLVCDSDENLKNKESVVQCLHILSSLRLIMQVALPQEHLCWIIFNGTIYIYTICRKLMVIGQSSKALEYLLWASMCMESLVPLLSLRYLTWRATLYTAVCQCCYDCHAGIHGEAFARRALAKIDELRQLELMSSSKSQEESRRYFREATMKMAVMIFKRGVFESRRKNKAVFRPKIRINLREVQTLSWPRTVTERLLDEMFDSTASQFLAVLEALSDSNRRILQTGPIVTDEVEIHDVVSELFMAGKELLIMSNIGADGMLDFPKTSLLELMIGRKDVISVDAAVKFIKLAFTYEEWSLFESSAVHLIYFLQRQDDPESKKAEKDLTLLIAMEPLINVKRNKGLIFPLENYKEGQSTQIYLKKIAVHDTCLKTCGYSEDIFHLAATLYVCVCTAPQDVQPDKEIVVDTIMFLWQKCKLGIQRLNISRNDYAKFTQKISTNKWIYLLWQINEVIHCYKMEDIDIVVVAEVTLRLSEILESLGSPGRKFKQSLDVPLREGTNKFPGAPKGITEILPILQKNPVEQLLFAYKLLDRAIGGINLNCMLTSLPNGSSVIDHCYAKRTHHIDGDTYKPLASNSFMMDLHLELIQAQHRIAVVLLDKLQVLQTPTVSKDISTKGPEKLKQSGSTDCFTELNIMNKIKKNTLSKAIYLMQKALLIFEKDATSTSSWELLMEAYSLIQRIEAEQNALYSYQKYLESSKRKKSRVPPPPILLSRTHCSVTLKPAPFTSEVKVSWYCILGCKAEGSYGKVRLNNNHLPNSGEAIPADGKSVFEVKGLETNEKYVFAVAAYSNNGKLVGGAIGETTKPILVYPPLSTITARMFLTQVAYQVGNYELAKKVFSPVWDYFVASPLQDEQSVICLSNIITITQRRLHSDILAETSSILLYLFLRNIFVTSDIKIKEENLFCDNIKGNEIFPSQQIARLIECERVLVALELSNFLNDSSYALQAVTQCYGLLAPIIYHNIVLVPVVQILIKCIVVLQGLPSIVCSKKHTASFESIQHMIACCIFYITKILRSWREYDLAVMIINYGKKMLDITPGCKSLFDGSNEQEEMPEEDSSKKSLKTKKPQQILLPEKINEQLALLETHLLKLTKQYVTSELSGGEDPIFLYPVVLNWSVKGAVKEVMKFKQKPRFLEFFTQVMLKCMNEEKFHLMVEVTTPVHDFLKRRNESLLGLIKVKYKDSALNKKANKSLKFKAAVMEIGRSAEMQQRIRSKKKETLRDFIFKNPAISEMVAHERNRRTSVRKAAQRYLMDYLNPLILSYVKRKRFHRLSLEEMPWRAQMNLYLAGAHFNLVLQKLWECTKMKFGTSHMMVSFRSCDPNMFSLYNSGTVLPTRKLTVENYKAMLDFLLTAKKRKANLPSDAEEFSTFINSIMSDENMSKTQTVYDSDSQSGSSAKEKDRGANLCVMDHFMKIFLYCRRAMVLAHRGGYWTLLQNCCRALWNFTQELQILLKQAVDLDKTFPISQDGFLCTSVLPFYLGAELLIDMLIQLQNTSSIKPIEDKGEFSVPSCYGNIKNDNGGSSLTFEHPLDDVNVVDLKWIHDFVLKSLEVLYQVEKWETLVSLAIQFNTVSHERYTEQVTPLLVYAQRQLLLRIQKFKGPDITQQPCARYEAEYGEKITCRNFIGKQLKINSSTIEATSNCTDLLKMLISSEYSRAKALVCVPVDVTDTLRCFRETLEKSKYHNRSIRHSRKLLSLFLAQTQDVLQASNQRSLKVQALHSLGSLLIFAEKKRAAFKCWCQALDDIFRKPDVLHTWKEFGPSLTNVTNSHSPPGFKDYSEEFLSRVGIWGCLQGAVISAKIAQFIKSLNVEKKTDCCILSALLFQGLLRTTLPHPKAERCYAQYEITQLLPGIELFSDRYRADICSVIASLYYIIRELHFVRQNLIVLPLLALYQYFVSGICQDITRNLEARILKIEVLIDLRFFSEAFYEISQIFYGKNMPCPIPAGYKATGKMKIFQSFDSGKLLTSKENIQAIDELRNKGLPAVLVTIGQPHLLNKFNFVKAYFFLSVAATINCVPENKFKTVITNKSKPNLPNLEEIYSKDDGSSFYNLTKLKDEITLSMLKSMLLMEAEDRLNFLLSEVEQKTLSQCSAGELEIVVEARLQLAAVALQRHRAAYSAAIVFSTLTLLQDSKLFEKKVVQDDTENPVSPGTSVTENKDDSEFLDPISLNAREYFNIHLWLRCRLALVTAFVAQIHGIGIVKEDDMTDCLSLINEVCMEAKSAGDTELQAEFLTQAVILGLQEKHLKADIMTNLQDIIHLLEGNEFISPQSRLTLARSLVLLDDLTKAEKFKESPSSKTGKLNLLTRAHSILTEQMLAFGETIEFRSSNTKYANPLQPLKNIYLPHVMLLAKIKMRIGHTVAKQVYYKNKRKDPSKWLPALHLFDVALKLCRTTAVEEHEVEAEILFQKGKIERQILMEEKSPSFQLESLYEAIQLSLKNDQNSGLIRDSYLEMALLYFHLKKPKIKISGSPLTLKPPLRRSSSVKETSANKFEMYSSLAWIAIRAAAQVSEAVLAINLLIGKKNTRMHKVNQVALPNIPEFAALDLLSSYTDYLLDNYQVLFQTSCTFLYQNDDVCDSADGRKKTQTKVDITWILLLRYYIHLQRINNLSKLLASATPVSGISLPDDTLLTSLYNSELILRQKEVHFFLKKFLQLYSSSCIDEFPKELLCQLENPPLSEKDLRESSAKLYRDSSVQSILSFKPVSGSSCVDITPIEMVTQASNKELCFQWYIPPLDRPPKETEPMVLLLYAYNLKPLKISDVRHSTYNSTCVGSLWIPLNRVIAIHEKLSNLAQIAELSLPAAPEITSNENIYEVEVEEESVDNEMEDMIIQCCSEIASLFLNDKEPTPLSEVPFDISLPSIFNLERLFDLANGCILSGGSLFNWIVSIIP

Gene

CFAP54

Protein

Cilia- and flagella-associated protein 54

Organism

Chlamydomonas reinhardtii

Length

3081 amino acids

Similarity

Belongs to the CFAP54 family.

Mass

317.779 kDa

Sequence

MASEVIALCHSFEQELAKSLNVLPPVSASKPDAHDAHLNHHRLSQRIAESVSYYAGRLPAYASVPRILVFGDKLFRAEQYQLALQACYKHIRGLELHSSRENLPRMDAQARLSSHVQACFGCAACEAALLLASDGSVKHPDTLQWLVSCLAQLRAAMSLALPDERLYWLVLNGTVHVYGIAKAMITAGFAEQALPALVFCIKALEGHVAFAAPKYLPWRTQLYTWAVYGLADCGAVEQARALLADGLKRLEMLVALQKLDPVPAAPAVQAAFAAARGALVGLQLRVEMAAGAAVTPVLAQLSAGAAGAGAVGAAGPTARAGLAALVEALHVPHRRVVRTEAVSGGPLKELFDAAMAVAAPLIGDLKKATEAAAAADAAAAAAAVAADAASAEAETAGGADAAAPADTGAQQQASAAAAAADEAAVAASAALGAAQEALPCALHKGLLCAAYNLEQWKQFEELASLATSRSDVVYADAVPTGTGSTTTTAAAAADVDQTAAQLGTAASILTALRQLSTAPGVESLRTLAAMLQQALSRGITVSGTAGAAPPPPPRRVSMTGMLAGGSASPPNGSSGAGGAAATLTATAAGITQTAGSPSHNGGAAGATASAGGGAAGAPPRPQQSSLAPWQQLRDLIADASLALYGSARPLIDGVFCADDKEAGLVAELLAACHSAWAAVELDDGELRVAAALKLALLLEEEGRLLAAREVLMQAKSVVEQSRVELMVANRRAPDEHLRWVTASRSQPSDDTAALVQGMTASEQELACLQVDVLALLARVELGLGVSEQQGRATARRTAVMEEQAKRTAQSSIFGQRNAAELARDEARLVAAGATPPNPQMKERELLTACAKNPYERAVVLMQMTSFQGADAGRKTQLLQEAGDLLVKAQAAEDGLFAAQQPDLRARRDVPPQPKLLQRSPTSVTLVAHPPGPGLKQPPGARKPPSRYVAYCKSFGAGVGLSINKTATEYPGSGVSVPLGQPVTIQVALPCTLPQLRAPFLEEQVARLKSARLLVLGMEVAALLPDEPLMQEGALRTYGLLAPLLALRAPRSHLLHKALAACHAVLASLTNLVQDSLYRQEHQRSLAARVAAAVTYQLLRLSDEAGEVGAAAHFGRLQLELLKAYDPRFALAGRPALLPGAELQEEASQLHDVLLQHPKLSEWAPEPLVERQKDASDLVARVLPVLGTPAPMDTWSQALGFETAAEHPRWVELVVRMVEAAVRKGNPGNATVVAEQLTWWVRARLRRPPPPPLDAYEAEAAEAAAAGGTAPPWPAKWKLEEAAAALDAATVAASFEPPPVPSTEGMSPEEASAALARHAAVAAAAEATARQRLAAVLLLQKRMPALLARKRLIEKMRENRKRWSPWMARLNLVLGLQAAADARRYAANAPARARAAAAAAEAAAAAADAPGPETSGVAGSRPGTAAVNMPPPVPDPSAAGPPPLTPPEGITPPLQAMMHFARAAHLAARGGAWVEVGNAARHAWNLARATLSADPALTAPLPPVRWERGDAPQPAVAPESILVPAGAGDAGGKKGSKKGGKDDKKKDDKAPAKTPSSPKGGARSSARSKKGFPVEEAPPPPRTYPVVVGARPNMQRAARSLADAVLELVSALRDGLQVYTWVAPVNPRHRFDGPPPRRAALAASASTAGAGLGEEERPVTARVTDSEFSYGSDLQADIWFKEGPLDLAWVSRFLGLAAVVLSRGERWHALVEAGRQWARLSEGAFNERIMPWLLQAAPKAGVDPAPFQSAMDALIRDKNQALDQLDKVRTLVRERLGDTPLMAQSMGHKVRKRKTRAAILAAGPGSGAGGGGGSGLPDSDRASLVSAAYTYRTASTYKTKASQPDFLRIPGEYEKVIEVLKRRNEKGAMLLALHELGDVHAHFGNWGGAATSWNDTLDTLLGPYQALRNWRGRLDGMSPAGTLQAYGLHGLLLGCVLAGKLARYVHHDHLHLRLEAHRLTARLAFCAFSAHLGHPQRRAGFATYTPRELWAAGTDAWLVWSDPYRCPVVDLAGALEGAAAALLDAGLALEALPVLALWEHVTRHVLRNLHGTVLCRLLRVRALVALGLLAEAVEVTGGLMGAAALPDPTLDSDYVLKDTSGAVVEPVPAPPYDNSKLPGEPGNKAALTHIADTPLAPAVEKLYGSWLVAHLALARAQVLMLAGSVPNQWRGVDWRTGERTAAPKPASPAKGAAKGAAAAAPEPPGAGLPEPVEPVMLERAHVLLRKALAMASGEDQPPSEEPSSAGKPAAAGKPAPARAPSPGRAKSPTGKGKGKGGAGDGAGSAAAAPPEVPGPPPPPPPSASQRAEVNVRALLLMSELEQLRWMPSRGLAHALEAARFLGEHADHVNTPQQTDNDELERYTLAPALWFLARGAAVRCAAALGHAAHVHELVAAATSAHAPSEPGSAKVPSGLPELLHCTGMAHVAALTLAAEGRTSDALAALAAVAARYRSLCVYDGRLAAVLLDAAALRDRLGLREDAAELTAQGLAVAEGYCLELGLGEALEAPELTNVYLDGTALYAHALGAAAVHASRRQQHAEAERCAARAVLLLRSHTRALPATHAAALLLLGRTCRMVALCGDGVPVDGQPTLASGAPPASTATLTSAGAGAPGDPAATAVAAGTARAAAGGFNASAGALARTATAGRGGGSAGSSGGGVAATAAKLSAARSALCASITLAAVDGGHLRSLMRGALLELGSIFIAGLDARSAAACLRAGHAAAAKADLVALSSHTLAPVAAAQLPDWALAHVRGQEALFGKKSSNGAISGAAGAAGSARPVATSSSGARPPGTPPGGKPGAGGGSGDGLSDADAARMVFCLLGGLLKGLEALPVGGGARARGEAQVAALHAALRAACAKYGTDACFAEPPLPPSPPDAVPPPPEGSVIVQWHCQDGCWQEARSWRAEGSSGAPDGPLSDSALLALQPVPAYASLLFVVAAPSHDGSPGPHCGEVTFAVKDVRELQRRAKALRARVEAPKAATDILGYAAPSQVELGELLRAAERLLSAVPRNSEDGSSSAGFSAADSGLGGFGSSELMEGEVRPELDVAFLCKLEALLALEAGLDVNDKTLGSWLVQTLPVMM