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CDKAL1

Gene
CDKAL1
Protein
Threonylcarbamoyladenosine tRNA methylthiotransferase
Organism
Homo sapiens
Length
579 amino acids
Function
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Similarity
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
Mass
65.111 kDa
Sequence
MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAYGYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLGQKKDNGRRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVDRAKQSFQEGVCEIWLTSEDTGAYGRDIGTNLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEEMAKILNHPRVYAFLHIPVQSASDSVLMEMKREYCVADFKRVVDFLKEKVPGITIATDIICGFPGETDQDFQETVKLVEEYKFPSLFINQFYPRPGTPAAKMEQVPAQVKKQRTKDLSRVFHSYSPYDHKIGERQQVLVTEESFDSKFYVAHNQFYEQVLVPKNPAFMGKMVEVDIYESGKHFMKGQPVSDAKVYTPSISKPLAKGEVSGLTKDFRNGLGNQLSSGSHTSAASQCDSASSRMVLPMPRLHQDCALRMSVGLALLGLLFAFFVKVYN

Gene
Cdkal1
Protein
Threonylcarbamoyladenosine tRNA methylthiotransferase
Organism
Mus musculus
Length
578 amino acids
Function
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Similarity
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
Mass
65.289 kDa
Sequence
MPSASCDVLLDDIEDIISQEDSKPQDRQFSRKHVFPKVRRRNTQKYLQEEPRPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAYGYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKVVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLGQKKDNGKRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVERAKQSFQEGVCEIWLTSEDTGAYGRDIGTDLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEEMAKILNHPRVYAFLHIPVQSASDSVLMDMKREYCVADFKRVVDFLKEKVPGITIATDIICGFPGETDQDFQETVKLVEEYKFPSLFINQFYPRPGTPAAKAEQVPAHVKKQRTKDLSRVFHSYNPYDHKIGERQQVLVTEESFDSKFYVAHNRFYEQVLVPKNPAFMGKMVEVDIYESGKHFLKGQPVSETRVYTPSISKPLAKGEVSGLTKEFRNRLGNHPNGTSDTCPATQHGSAYSRMVLQMSQYDCALKVATGLALLALLLHFWPDSLLTM

Gene
cdkal1
Protein
Threonylcarbamoyladenosine tRNA methylthiotransferase
Organism
Xenopus laevis
Length
556 amino acids
Function
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Similarity
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
Mass
62.906 kDa
Sequence
MPAVCESLLDDIEDMVSATDPKPHDRQSARKNIVPRARKRNKNNIQEEEPPADSTIPGTQKIWIRTWGCSHNNSDGEYMAGQLAAYGYSITEQPEKADLWLLNSCTVKSPAEDHFRNSIKKAQEANKKVVVSGCVPQAQPRQDYMKGLSIIGVQQIDRVVEVVEETIKGHSVRLLGQKKDNGKRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGELASYPVEELVDRATQSFQEGVCEIWLTSEDTGAYGRDIGTDLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEEMAKILNHPRVYAFLHIPVQSASDSVLMDMKREYCIADFKRVVDFLKERVPGITIATDIICGFPGETDEDFKETLKLVEEYKFPSLFINQFYPRPGTPAAKMEQVLAHVKKRRTKELSQLFHSYDPYDHKIGQKQQVLVTEESFDSQYYVAHNRFYEQVLVPKDPDFMGKMVEVKIFEAGKHFMKGQPVQDSYIYTPSITKPLAKGEVSGLTEELKPPNNIPKSETLLEKHWERLQVFLFLTALLAAVIAFVGTKLV

Gene
cdkal1
Protein
Threonylcarbamoyladenosine tRNA methylthiotransferase
Organism
Xenopus tropicalis
Length
553 amino acids
Function
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Similarity
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
Mass
62.25 kDa
Sequence
MPAACESLLDDIEDIVSATDPKPHDRQNARQNIVPRARKRNKNKIQEEEPPADSTIPGTQKIWIRTWGCSHNNSDGEYMAGQLAAYGYSITEQPEQADLWLLNSCTVKSPAEDHFRNSIKKAQEANKKVVLSGCVPQAQPRQEYMKGLSIIGVQQIDRVVEVVEETIKGHSVRLLGQKKDNGKRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGELASYPVEELVDRAAQSFQEGVCEIWLTSEDTGAYGRDIGTDLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEEMAKILNHPRVYAFLHIPVQSASDSVLMDMKREYCIADFKRVVDFLKERVPGITIATDIICGFPGETDEDFKETLKLVEEYKFPSLFINQFYPRPGTPAAKMEQVPAHVKKQRTKELSQLFHSYSPYDHKIGEEQHVLVTEESFDSQYYVSHNRFYEQVLVPKDPAFVGKMVEVKIFEAGKHFMKGQPVQDSYIYTPSITKPLAKGEVSGLTEESKPPNNPESLLQTSREGLQTFFFVTALLAAVIAFVGIKLL