Protein
Serine/threonine-protein kinase CDG1
Organism
Arabidopsis thaliana
Function
Serine/threonine-protein kinase involved in the positive regulation of brassinosteroid (BR) signaling and plant growth. Mediates BR signal transduction from BRI1 receptor kinase to BSU1 phosphatase. After activation by phosphorylation at Ser-234 by BRI1, CDG1 phosphorylates BSU1 at 'Ser-764' in the phosphatase domain, increasing the ability of BSU1 to inactivate the negative regulator of BR signaling ASK7/BIN2 by dephosphorylation at 'Tyr-200'. The full kinase activity of CDG1 is required for its biological function.
Similarity
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Sequence
MVSCLCFRPSRKTKLKDKSHKRSIRNQTSSSSAQPAGTAKEVDSSSSQTVVQDSSRYRCQIFSYRELAIATNSFRNESLIGRGGFGTVYKGRLSTGQNIAVKMLDQSGIQGDKEFLVEVLMLSLLHHRNLVHLFGYCAEGDQRLVVYEYMPLGSVEDHLYDLSEGQEALDWKTRMKIALGAAKGLAFLHNEAQPPVIYRDLKTSNILLDHDYKPKLSDFGLAKFGPSDDMSHVSTRVMGTHGYCAPEYANTGKLTLKSDIYSFGVVLLELISGRKALMPSSECVGNQSRYLVHWARPLFLNGRIRQIVDPRLARKGGFSNILLYRGIEVAFLCLAEEANARPSISQVVECLKYIIDHTIRKERRTRRRLLGGNKDGAGTSRSPDETMMRMLEEEEEYVTSEEAIERRRVIVDDARTWAGMNRRGATPPTPTP