Organism
Xenopus tropicalis
Function
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Contributes to CPC function by facilitating loading of the CPC onto chromosomes (By similarity).
Similarity
Belongs to the borealin family.
Sequence
MPPKRNRKRLGTRGEGSGDSGVGMFERNDAVQEQKKEKIRLFMQDFVQQGKDRLAELKKDLESLSTTADKALEVELLKMPLAIRHMKVQDYLSLMGGDKTAVAAAAVKLDCSVDELSEPKLVRKSSKKVKVTTNVEYQDDIRTKVMTTTGKTRTVQKVPKSKSMLSLTGKNSKKTTALTRSVSATPIDKASKKLLVTNSSSKPAQRSSRTAMTPLSRSARSDAVFSFGDGTFLDEGVPFVKIPLADGQTVFSAGDDLDSLNVELLRGDTVQHIHNLVGQLTNLCAKASIQQHGNTL