CCPG1

Cell cycle progression protein 1

806 amino acids

Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42. May be involved in cell cycle regulation (By similarity).

Belongs to the CCPG1 family.

93.471 kDa

MSENSSDSDSSCGWTVISHEGSDIEMLNSVTPTNSCEPAPECSSLEQEELQALQLEQGESSQNGTVLMEETAYPALEETSSTIEAEEEKIPEDNIYIGTASDDSDIVTLEPPKLEEIGNQEVVIVEEAQSSEDFNMGSSSSSQYTFCQPETVFSSQPSDDESSSDETSNQPSPAFRRRRARKKTVSTSESEDRLVAEQETEPSKESKRQFSSGLNKCVILALVIAVSMGFGHFYGTIQIQKRQQLVRKIHEDELNDMKDYLSQCQQEQGSFIDYKSLKENLARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTELVKENQKLKQHLEEEKQKKHSFLSQRETLLTEAKMLKRELERERLVTTALRGELQQLSGSQLHGKSDSPNVYTEKKEIAILRERLTELERKLTFEQQRSDLWERLYVEAKDQSGKQETDGKKKVGRGNHRAKNKSKETFLGSVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTTKNIFDEKGNKRFGATKAAAEKPRTVFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHFKEFRKNTNSRKCSPGHACRENSHSFRKACYGVFDCAQQESISLFNTVVNPIRMDEFRQIIQRYMLKELDTFCHWNELDRFINKFFLNGVFIHDQKLFTDFVNDVKDYLRNMKEYQVDNDGVFEKLDEYIYRHFFGHTFSPPYGPSRPDKKQRMVNIENSRHRKQEQKHLQPQPYKREGKWHKYGRTNGRQMANLEIELGQLPFDPQY

CCPG1

Cell cycle progression protein 1

801 amino acids

May be involved in the regulation of Rho-mediated signaling pathways and in cell cycle regulation.

Belongs to the CCPG1 family.

93.485 kDa

MSENYSDSDSSCGWTVINHEGSDIETVTSENGSSNDNHEFVSEEYVSLQEVEQPIELQAQDSTDGEIPVVDNTLSALEETQTVPEERKEKVHDDSSCIGTISDDSDIVTLEAPKGEETPSQEEAPADGEEAPSSEDFNMGSSSSSQYAFSQPETVFPSQASDDESSSDETSNQSSPTVRRRRAKRRLISCSEAESGSPVGPEPEPPQEQQHKRQFSSGLNRCIILALVIAISMGFGHFYGTIQIQKRQQLLTKTRELKDDLYQCQQEQGDKVGSLKGDLATCLTSTEVEKKSFESQKKSLAAENQHLRESLEKEEKALVSLQEELRKLRQQIRNLEDKGTSTESIVMENQKLREHLEEEKQRNHNFRRQKETLFAEAQMLRRELDKERHVTEALKKELEQLSSRQTPDSVNDDDTLRENEEIETLRGRLVELEKKLNFEQQRSDLWEKLYVEAKDLTEKQEMNEKGQKRGAKGQSKSKKKSKESFFGSVKETFDVMKNSAKEFVRHHKEKIKQAKEAVKEKLKKFSDSVKSTFRHFKDTTKTILDEKEKKPNEKKYEANKKARTFYREHNLYENLKQSHYRRPNVPKDFRDGRRHHFTAFEKDTDSQKCLNDPLCSRKHQFDLKGCSGIFECANQEFVSLFNRVSDPIGVDEFNRLMRKYLQQVVHNFRHWRELENFINKFFHNGFFIHDQMLFTDFVNDVKDYLEDMKEYQNKNEKVFDDLDKYIYRYYFQYDNSPQYGPSRPKRPSFTQTENPRHEKQAQKYHHRNKREGKWHKHGRTNGRHMANLEIELGQLPFDPKY

CCPG1

Cell cycle progression protein 1

757 amino acids

Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation.

Belongs to the CCPG1 family.

87.34 kDa

MSENSSDSDSSCGWTVISHEGSDIEMLNSVTPTDSCEPAPECSSLEQEELQALQIEQGESSQNGTVLMEETAYPALEETSSTIEAEEQKIPEDSIYIGTASDDSDIVTLEPPKLEEIGNQEVVIVEEAQSSEDFNMGSSSSSQYTFCQPETVFSSQPSDDESSSDETSNQPSPAFRRRRARKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNKCVILALVIAISMGFGHFYGTIQIQKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKSLKENLARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTELVKENQKLKQHLEEEKQKKHSFLSQRETLLTEAKMLKRELERERLVTTALRGELQQLSGSQLHGKSDSPNVYTEKKEIAILRERLTELERKLTFEQQRSDLWERLYVEAKDQNGKQGTDGKKKGGRGSHRAKNKSKETFLGSVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTTKNIFDEKGNKRFGATKEAAEKPRTVFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHFKEFRKNTNSKKCSPGHDCRENSHSFRKACSGVFDCAQQESMSLFNTVVNPIRMDEFRQIIQRYMLKELDTFCHWNELDQFINKFFLNGVFIHDQKLFTDFVNDVKDYLRNMKEYEVDNDGVFEKLDEYIYRHFFGHTFSPPYGPRSVYIKPCHYSSL

Ccpg1

Cell cycle progression protein 1

753 amino acids

Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42. May be involved in cell cycle regulation.

Belongs to the CCPG1 family.

86.126 kDa

MSESSSDSDSSCGWTVINHEGSDIEIVNSATASDNCGLTLECSLVEQEELPVLYVGHGGEESSANNTSSVGETMLSSMRETKSAAEVEEAPSPEDNVYFGTTSDDSDIVTLEPPKLEEMGNQEVTIQEAPSSDDLNMGSSSSSQYAFCQPEPVFSSQPSDEESSSDDTSHEPSPAPRRRRNRKKTVSISESEEPPLAEPEDEPSKEPSKRHFSRGLNKCVILALVIAVSMGFGHFYGTIQIQKQLVRKTHEDELDGVKGYLSQRKQEQESFLDFKSLKENLERCWTVTESEKITFETQKKNLAAENQYLRISLEKEEQALSSLQEELRQLREQIRLLEDKGTSTQLVRENQVLKQYLEVEKQKTDSFLREREMLLEEARMLKRDLEREQLTAMALRAELEQFIPGQAQSRAESPSVQTEEKEVGLLQQRLAELEQKLIFEQQRSDLWERLYVEAKDQHGKQETDGRKRGSRGSHRAKSKSKETFLGTVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTTKNIFDEKGSKRFRAPKEAATEKTRTAYSYSSYSQQEAPNQNQNCRRPSAQRDGGREKPSHSEEIRKNANSYTYKAKSDCRGTHSTRRVCSGMFECAGQEAISPVNKASPVRMNDFKQLIHWYLLNELETFHHWKELDQFISPFFPNGVFRHDQQLFADFVDDVKGYLKSIKEYRVEDGNLEKLDGCIYRHFGHVFALPFGPRSVYIKPCYYNSF