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CCL13

Gene
CCL13
Protein
C-C motif chemokine 13
Organism
Canis lupus familiaris
Length
98 amino acids
Function
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors (By similarity).
Similarity
Belongs to the intercrine beta (chemokine CC) family.
Mass
10.98 kDa
Sequence
MKVSAALLCLLLTAAILTTQVPAQPDALSALFTCCFTFNNKKIPLQRLESYRITSSHCPRKAVIFSTKLAKAICADPKEKWVQDYVKHLDQRTQTPKT

Gene
CCL13
Protein
C-C motif chemokine 13
Organism
Homo sapiens
Length
98 amino acids
Function
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
Similarity
Belongs to the intercrine beta (chemokine CC) family.
Mass
10.986 kDa
Sequence
MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT