ccl1

Cytochrome c-type biogenesis protein ccl1

653 amino acids

Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.

Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

70.552 kDa

MIVETGHFALILALCVALVQAVIPLVGAQKGWSGWMAVATPAALAQFGLIAIAFAALTYAFVTSDFSLKLVYENSHTDKPMLYKVTGVWGNHEGSMLLWVLILAMFGAAAAAFGGALPERLRARVLAVQGTIGVAFLVFVLFTSNPFLRLEEAPFNGRDMNPLLQDPGLAFHPPFLYLGYVGLSMAFSFAVAALIEGRVDAAWARWVRPWTLAAWIFLTIGIALGSWWAYYELGWGGFWFWDPVENASLMPWLLAAALLHSAIVVEKREALKSWTILLAIMAFGFSLIGTFLVRSGVISSVHSFANDPERGVFILFILAFFTGGALTLYAARASEMQAKGLFSMVSRESALVMNNVLLAVAALVVFTGTVWPLIAELFWDRKLSVGAPFFEKAFTPFMVGLALLLPLGSMMPWKRASLGKLVRPLLPALVLTLAVLALVWVMATGRPMLALGAAGLGAWILFGALAEIWQRAGRTPGRILRLPRADWGKAFAHGGLGIVFAGVGLLMAGQVEDIRVAKAGDSFEVAGYTITLVSVEDVPGPNFTAKTATMEVRQGGKLVATLHPEKRIYPVQAMPTTEADIDNGFWRDVYLVIGDPQEGGGWAVRTYVKPFANWIWAGCLLMAFGGGLSLTDRRYRSAAGARRATVADAVAAE

CCL1

Cyclin CCL1

393 amino acids

Regulatory component of the TFIIK complex (KIN28-CCL1 dimer) which is the protein kinase component of transcription factor IIH (TFIIH) and phosphorylates the C-terminal domain of RNA polymerase II during transition from transcription to elongation after preinitiation complex (PIC) formation, thereby positively regulating transcription. TFIIH (or factor B) is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has DNA-dependent ATPase activity and is essential for polymerase II transcription in vitro.

Belongs to the cyclin family. Cyclin C subfamily.

45.21 kDa

MTDIQLNGKSTLDTPSATMSAKEKEAKLKSADENNKPPNYKRISDDDLYRHSSQYRMWSYTKDQLQEKRVDTNARAIAYIEENLLKFREAHNLTEEEIKVLEAKAIPLTMEEELDLVNFYAKKVQVIAQHLNLPTEVVATAISFFRRFFLENSVMQIDPKSIVHTTIFLACKSENYFISVDSFAQKAKSTRDSVLKFEFKLLESLKFSLLNHHPYKPLHGFFLDIQNVLYGKVDLNYMGQIYDRCKKRITAALLTDVVYFYTPPQITLATLLIEDEALVTRYLETKFPSREGSQESVPGNEKEEPQNDASTTEKNKEKSTESEEYSIDSAKLLTIIRECKSIIEDCKPPSTEEAKKIAAKNYYCQNPSTLIQKLKRKLNGEDTSSTVEKKQKT

CCL1

C-C motif chemokine 1

96 amino acids

Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.

Belongs to the intercrine beta (chemokine CC) family.

10.992 kDa

MQIITTALVCLLLAGMWPEDVDSKSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSICSNEGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK

Ccl1

C-C motif chemokine 1

92 amino acids

Cytokine that is chemotactic for neutrophils.

Belongs to the intercrine beta (chemokine CC) family.

10.276 kDa

MKPTAMALMCLLLAAVWIQDVDSKSMLTVSNSCCLNTLKKELPLKFIQCYRKMGSSCPDPPAVVFRLNKGRESCASTNKTWVQNHLKKVNPC