CCDC93

Coiled-coil domain-containing protein 93

631 amino acids

(Microbial infection) The CCC complex, in collaboration with the heterotrimeric retriever complex, mediates the exit of human papillomavirus to the cell surface.

Belongs to the CCDC93 family.

73.198 kDa

MGLPRGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEMLLSKVKAKAS

Ccdc93

Coiled-coil domain-containing protein 93

629 amino acids

Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C.

Belongs to the CCDC93 family.

72.603 kDa

MGLPKGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCSFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRSYSISQFQKTYSLPEDDDFIKRKDKAVKTVVGLSDAYKPRRKYRRQRGAEELPDEESRVHSTLLEYGRRYGFSRQSKTEKAEDKKTALAAGLSAAEKVDAHEEDELQAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSEEIKQIVSEYAGKQSELSAEESPEKLGTSQLHQRKVISLNKQILQKSKHLEELQANHTSLKAKYSDRKKTLTELKDHGEKLDKEQAALEKLEAKADPSMLQNLRALVAMNESLKSQEQEFKAHCREEMARLQQEIETLKAERAPGEKIISGGEPQGALTSTMTHNEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNELLLSKIKAKAS

Ccdc93

Coiled-coil domain-containing protein 93

629 amino acids

Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C.

Belongs to the CCDC93 family.

72.636 kDa

MGLPKGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCSFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRSYSISQFQKTYSLPEDDDFIKRKDKAIQTVVDLSDAYKPRRKYRRQQGAEELLDEESRVHSTLLEYGRRHGFSRQSKTEKAEDKKTALAAGLSAAEKTDAHEEDELQAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYEGKQSELSAEESPEKLGTSQLHQRKVISLNKQILQKTKHLEELQANHTSLQAKYSDKKKTLTELKNHGEKLDQEQAALEKLEAKADPSILQNLRALVAMNESLKSQEQEFKAHCREEMARLQQEIEILKAERAPGEKTISSGEPQGALTSTMTHNEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNELLLSKIKAKAS

CCDC93

Coiled-coil domain-containing protein 93

617 amino acids

May be involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery.

Belongs to the CCDC93 family.

71.719 kDa

MVVPRGQEHRAPQEVETREDEEQNIKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDIDIDLLFQENSTIGQKIALTEKIVSVLPKMKCPHRLEPHQIQGLDFIHIFPVVQWLVKRAIETREEMGDYIRSYSISQFQKTHRLPEDDEFMQRKEKAIKTVTDIFEVYKPQRKYKRQKGAEEILDEESKVHATLLEYGRRYGFSRQAGKTEQTEDKKIVLPSGLAAAGKAEPCDEDDLRAAEELRIKTLMTGMAAMATEEGKLTASTVGQIVGLQSDEIKQIVSEYAEKQSELSAEERPERLGAAQQHRRKVASLNKQILQKTKLLEELQAKFVDLQAKCTEAKKTLTEVESYSEKLDKELAALETIESQADSSVLQNLRMLVAINENLKSQEQEFKAHCREEMERLQQDIENLKAEAAENGEEEEPNKLIDQQYQTEKEKLQKIRLLLARRNREIAILQRKIDEVPSRAELTQYQKRFIELYSQVSATHKETKQFFTLYNTLDDKKVYLEKEVNLLNSIHDNFHQAMASSGSREQFLRQMEQIVEGIKQNRMKMEKKKQENKMRRDQLNDEYLELLEKQRLYFKTVKEFKEECRKNEMLLSKLKASSS

ccdc93

Coiled-coil domain-containing protein 93

610 amino acids

May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery.

Belongs to the CCDC93 family.

70.951 kDa

MAARGETPEVETREDEEQGVKLAEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDIDVDLLFQENSTIGQKIALTEKIVSVLPKMKCPHRLEPHQIQGLDFIHIFPVIQWLVKRAIETRQEMGDYIRSYSVSQFHKEHSLPEDQDFELRREKTVRTLSETLDVYRPRRKYKRQGGSSELMDEESRVHSTLLEYGRRYGLSKQMKPEKPEDRRVPVPQGLVGKGEVREEEEELRAEEELRIKALMTEMAATGMEEGRLTASTVGQIVGLQSKEIKQMVSEYAEKQSELSAEDRAEYLGAAQQHRRKVASLSKLIGQRKKLLDQLQEKASELQSGCGETRKQLTEVTSHMEKLDQELSVLENMESKADPSVLQKLRDLVAQNESLKAQEQQFRSKCREEMSRLQQNIDGLKAAATEHGEEKEQTQAFEQQYKAEREKLQKIRLLLARRNREIAILQRKIDEVPSRAELTQYQKRFIELYGQVSATHKETKQFFTLYNTLDDKKVYLEKEVNLLNSIHDNFQQAMASPSARDQFLRQMEQIVDGIRQSRNKMEKKKQENKMKRDQLNDEYLELLEKQRLYFKTVKEFKEECRKNETLLSKMKGPTP

ccdc93

Coiled-coil domain-containing protein 93

609 amino acids

May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery.

Belongs to the CCDC93 family.

71.028 kDa

MTARGETPEVETREDEEQSVKLAEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDIDVDLLFQENSTIGQKIALTEKIVSVLPKMKCPHRLEPHQIQGLDFIHIFPVIQWLVKRAIETRQEMGDYIRSYSVSQFQKEHSLPEDQEFEHRREKAVRTLSETLDVYRPRRKYKRQGGSAELMDEESRVHSTLLEYGRRYGLSKQMKPEKPEDRKVPVPQGLVGKGEVKEEEELRAEEELRIKALMTEMAAMGMEEGRLTASTVGQIVGLQSDEIKQMVSEYAEKQSELSAEDRPEYLGAAQQHRRKVASLNKQIGQRKKLLDQLQEKASELQSGSCEAKKQLTEVTSHMENLEQELLVLEKVESKADPSVLQKLRDLVAQNESLKLQEQQFRSKCREEMSRLQQNIDSLKAAATEHGEEKEQSQAFEQQYKAEKEKLQKIRLLLARRNREIAILHRKIDEVPSRAELTQYQKRFIELYGQVSATHKETKQFFTLYNTLDDKKVYLEKEVNLLNSVHDNFQQAMASPSVRDQFLRQMEQIVDGIRQSRNKMEKKKQENKMKRDQLNDEYLELLEKQRLYFKTVKEFREECRRNETLLTKMKGQTP