Protein
Pentafunctional AROM polypeptide
Organism
Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Sequence
MAVADDTKADLLKVSILGKESIHCGFHLTPYIVQTVLTTLPSSTYVLITDDNIAKLHLNKFEEAFAKGIEKSAANPKPRFLSHVIPPGETSKSREGKARIEDFLLFHKCTRDSVILALGGGVIGDLVGFVAATFMRGVRFCQIPTTLLAMVDSSVGGKTAIDTPHGKNLIGAFWQPEYIFIDAAYLETLPTREFSNGMAEVVKTAAIWDEKEFTSLESRSAELFAAIQTPSTNYAGRTLETRSEAQKLLLSTIAASIGVKAHIVTIDERETGLRNLVNFGHSIGHAIEAVLTPTILHGECVSIGMILEAELSRQLGILTQVGVGRLTRCLKAYNLPTSLSAPLIASLPQASLLTVPRLLDIMRIDKKNSGTNKKIVLLKRIGETYEQKASIVEDKAIEKTLAEAVTVVPSIPTGNVKGSPGEVRMSTPGSKSISNRALVLAALAKGTCRLRNLLHSDDTQGAVFTWEDGGETLVVEGGEGTLTVPTPGKELYLGNAGTAARFLTTVCALAQPAPASVQPPSTNTVITGNARMKQRPIGPLVDALRANGCSIGYRESEGCLPLSIPPNSFKGGKIQLAASVSSQYVSSILLCAPYAQDANGVTLELVGGEVISQPYIDMTIAMMKTFGVEVTRRTDASGKLLDIYDIPRGTYVNPPVYNIESDASSATYPLAVAAITGTKCTIENIGSSSLQGDAKFAVEVLQKMGCEVHQTADETTVQGPPLGQLKAIEEVDMEVMTDAFLTASVLAAVANGGENKAMKITGIANQRVKECNRIRAMMDELAKFGVHTTEQELGLTIYAVPISQLKKNVSVHCYDDHRVAMAFSVLSTVVEGAIIEEKRCVEKTWPGWWDDLENKIGIKVEGVDLAGLRAESSSAGVKESKPIDNSSILLIGMRGTGKTHIGQLAAASLPGWSFVDADHYFESKLKTGVKDFVKNEGWEKFREEELAVLAELIGLGVDGKAVSSPSSYSKNHVISLGGGIVETPAARSLLKAYLAKGGRVVHITRPIDEIVRYLNVETARPAYEEPILDVWKRREPWYKECSGWEFGNVVVEAPQGQAQAANVEAGPGKTKCVKTLAGRNEVKRFFGHLAGINPNFTHGGSVEGQQRRTYFLCLTYPDVRHAFPYIDELTEGADALELRVDLLKDAKAPEAPFPSVAYVKDQVTALRRVTGLPIIYTVRTKAQGGAFPDGNAKEYKELVEAGVRLGVEYLDVEVASIFSDKEVADLSKRTKKAGSTLVIASWHDWSGKMQWDGEDVKRKYDEARKFGDLVKIVGKAEKLEDNFKLLSFVKSATSLPNSPPIIAINMSTLGQSSRILNTTFTPVSHPLLPTKAAPGQLSFKQIQQALHLLGLLPSKHFHLFGTPIAHSMSPTLHNTGFELLGLPFKYGLLESKEVDCKEVRDVISDKEGFGGASVTIPFKVDVIELLDELTESAKEIGAVNTIIPVHRSSINAQGQEETTRVLVGDNTDWVGIRVCITQRVSEGELRNENTSGLVIGAGGTARAAIYALQDLGVPVIYLFNRTKEKAEDLAKAFVGGADKKWNGQLVVLDKLGGGWGDVGVAPRVIVSTVPASATALPSASTAAIAGQVDKSTNQIVLPADVFAYTSGSAVVVDMAYKPAETPLLKLAKELKEEGNWACVQGLEVLLEQGYIQFEKWTGRRCPKEQVSTRVWEKYGEV