Protein
Antimicrobial protein CAP18
Organism
Oryctolagus cuniculus
Function
CAP18 binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Has antibiotic activity.
Similarity
Belongs to the cathelicidin family.
Sequence
METHKHGPSLAWWSLLLLLLGLLMPPAIAQDLTYREAVLRAVDAFNQQSSEANLYRLLSMDPQQLEDAKPYTPQPVSFTVKETECPRTTWKLPEQCDFKEDGLVKRCVGTVTRYQAWDSFDIRCNRAQESPEPTGLRKRLRKFRNKIKEKLKKIGQKIQGFVPKLAPRTDY