Protein
Mitochondrial glycine transporter
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Function
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
Similarity
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
Sequence
MASSTGHLIGGFAGGLSSAVALQPLDLLKTRFQQTKGGTLWQTVKSLDTPWQLWRGTLPSAIRTSVGSALYLSSLNLMRTALAKRKQFDTADSVVTGKSSNLPQLSMYENLVTGAFARGTVGYITMPITIIKVRYESTLYNYKSIAEAAKSIAAQEGIRGFFRGFGPTCLRDAPYSGLYVLLYEKLKHTLPTILPKSLLQLDSEGRYTAYTSTAINSTSAILSASMATTVTAPFDTIKTRMQLEPTKFKTFWSTLTTIVTQEHPIKIFSGLSMRLTRKALSAGIAWGIYEELIKHFM